Vijaya B. Kolachalama, Ph.D.

Assistant Professor 


BS, Aerospace Engineering, Indian Institute of Technology, Kharagpur, West Bengal, India, 1998-2002
PhD, Mechanical Engineering, University of Southampton, Southampton, UK, 2003-2006
Postdoctoral Associate, Elazer Edelman Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA, 2006-2011
ORISE Fellow, Division of Cardiovascular Devices, Office of Device Evaluation, Center for Devices and Radiological Health, US Food and Drug Administration, Shady Grove, MD, USA, 2008-2010

Contact Information

Lab website to

Research Interests:

Our mission is to create methods to fit the science and not make science fit the methods.

Specifically, we are interested in the following questions that have clinical relevance:

Neurodegeneration – How can we develop software frameworks that can assist dementia screening in various real-world settings?
Digital pathology – How can we build clinical-grade software tools to complement the pathologist workflow?
We are also interested in the following frameworks that have computational relevance:

Domain generalization – Development of neural networks that can generalize well across multiple data cohorts
Representation learning – Construction of efficient neural models on high resolution data to process local and contextual information

Selected Publications

Kolachalama VB, Singh P, Lin CQ, Mun D, Belghasem ME, Henderson JM, Francis JM, Salant DJ, Chitalia VC. Association of Pathological Fibrosis With Renal Survival Using Deep Neural Networks. Kidney Int Rep. 2018 Jan 11;3(2):464-475.

Qiu S, Chang GH, Panagia M, Gopal DM, Au R, Kolachalama VB. Fusion of deep learning models of MRI scans, Mini-Mental State Examination, and logical memory test enhances diagnosis of mild cognitive impairment. Alzheimers Dement (Amst). 2018 Sep 28;10:737-749.

Li J, Ogrodnik M, Kolachalama VB, Lin H, Au R. Assessment of the Mid-Life Demographic and Lifestyle Risk Factors of Dementia Using Data from the Framingham Heart Study Offspring Cohort. J Alzheimers Dis. 2018;63(3):1119-1127.

Kolachalama VB, Shashar M, Alousi F, Shivanna S, Rijal K, Belghasem ME, Walker J, Matsuura S, Chang GH, Gibson CM, Dember LM, Francis JM, Ravid K, Chitalia VC. Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans. J Am Soc Nephrol. 2018 Mar;29(3):1063-1072.

Kolandaivelu K, O’Brien CC, Shazly T, Edelman ER, Kolachalama VB. Enhancing physiologic simulations using supervised learning on coarse mesh solutions. J R Soc Interface. 2015 Mar 6;12(104).

Kolachalama VB, Pacetti SD, Franses JW, Stankus JJ, Zhao HQ, Shazly T, Nikanorov A, Schwartz LB, Tzafriri AR, Edelman ER. Mechanisms of tissue uptake and retention in Zotarolimus-coated balloon therapy. Circulation. 2013 May 21;127(20):2047-55.