How gene profiling in emphysema is helping to find a cure
Press Release: BioMed Central August 31, 2012 Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States and is thought to affect almost three million people in the UK. New research published in BioMed Central’s open access journal Genome Medicine has identified genes whose activity is altered with increasing […]
Predictive molecular signature in lymphoma may direct targeted therapy
Press Release: Dana-Farber Cancer Institute September 10, 2012 Researchers from Dana-Farber Cancer Institute, the Broad Institute, Boston University and colleagues have found a molecular “signature” in a common form of lymphoma that identifies patients unlikely to respond to standard chemotherapy, and who might benefit instead from treatment with certain experimental targeted drugs. The discovery came from […]
Identifying smokers who are at high risk for developing lung cancer
Although only a subset of smokers develop lung cancer, we cannot determine which smokers are at highest risk for cancer development, nor do we know the signaling pathways altered early in the process of tumorigenesis in these individuals. On the basis of the concept that cigarette smoke creates a molecular field of injury throughout the respiratory tract, this […]