Amyloid Cardiomyopathy Program

Program Overview

The Amyloidosis Center of Boston Medical Center/Boston University School of Medicine is an international referral center for the diagnosis and treatment of systemic amyloidosis, a group of diseases caused by the abnormal folding and then accumulation of protein in various parts of the body, including the heart. The Amyloidosis center is internationally recognized in the treatment of amyloid disease, with many clinical trials ongoing that test the newest therapies. Over 4000 patients have been seen in the center, which was created in the early 1970’s.

The Amyloid Cardiomyopathy Program employs a multidisciplinary approach to this multiorgan disorder. Our cardiologists diagnose and treat the damage amyloidosis can cause in the heart and coordinate innovative care with other specialists at Boston Medical Center. Areas of active clinical and translational research relevant to cardiac amyloidosis include: cardiac imaging using magnetic resonance (MRI), echocardiography, and nuclear pyrophosphate (PYP) imaging, development of novel diagnostic tests that might identify amyloidosis, and studies examining the biochemical basis of amyloid toxicity.

For further information, to refer a patient with amyloidosis to the Amyloid Cardiomyopathy Program, or for information regarding ongoing research studies, please contact the Program office at (617) 638-4317, or visit

Our Team

Frederick L. Ruberg, M.D. Omar Siddiqi, M.D. Deepa Gopal, M.D.