Past and Present Lab Members

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Principal Investigator:

Katya Ravid, Professor of Medicine and Biochemistry, Boston University School of Medicine

Dr. K. Ravid, trained at the Technion and MIT, is an Established Investigator with the American Heart Association, has served on editorial and advisory boards and on ASH and Purines Scientific Committees, chaired local and national conferences, such as the Gordon Research Conference on cell biology of megakaryocytes and platelets, and is the recipient of several Awards in recognition of research and teaching, such as Boston University School of Medicine Educator of the Year Award in Graduate Medical Sciences, Sidney University Professorship Award, the Weizmann Institute Rosi and Max Varon Professorship Award, and as a long-standing ASMBM member was awarded the Fulbright Scholar Award.

Founding Director, Evans Center for Interdisciplinary Biomedical Research (

Training Program Director, NHLBI-funded Training Program in Cardiovascular Biology (


“Rewarding science is born out of creativity, tenacity and generosity.” (Katya Ravid)


Past and Current
Pre (PhD training)
or Post-doctoral
Training Period Prior Academic Degree Title of Research Project Current Position (past trainees)
Source of Support (current trainees)
Degree(s) Year(s) Institutions(s)
Chen, Wen-Chen











Harvard School of Public Health


Thrombopoietin-inducible genes


Research Associate, Dana Farber Cancer Institute, HMS, Boston, MA; then Dental school, Dentist in CA

Frances, Cynthia


Post 96-00 PhD 1996 Boston University School of Medicine Adenosine receptors in platelets and vascular smooth muscle Proctor & Gamble (consultant)
Sun, Shinshin (Ivon)


Post 95-99 PhD 1995 St. John University, NY Regulation of the endomitotic cell cycle in megakaryocytes Investigator, Assistant Professor,

North Shore-Long Island Jewish Research Institute

Phytochemical Lab

Manhasset, NY

Thompson, Alex*


Pre 95-99 MS 1990 University of Coleraine, Ireland Regulation of endomitosis in megakaryocytes Associate Professor in Translational Stem Cell Technology

Division of Cancer and Stem Cells,

Wolfson Centre for Stem Cells, Tissue Engineering & Modelling (STEM)

Centre for Biomedical Sciences

University of Nottingham, UK


Zhao, Zhihui




94-00 MD, PhD 1993


Beijing Med. Univ., China Adenosine receptors in platelets and vascular smooth muscle Sr. Director

Antibody & Protein Discovery

QLB Bio-therapeutics Inc. (2017-present);Sr. Scientist, Bioscience Technologies, Inc, Waltham, MA (2008-2017); Assistant Professor of Medicine, BUSM (2002-2008)

Zimmet, Jeffrey*


Pre P


95-98 BS 1993


Wesleyan Univ., CT Regulation of the endomitotic cell cycle in megakaryocytes Associate Professor of Medicine, Univ California San Francisco; Interventional Cardiology, San Francisco VAMC
Cataldo, Leah


Post 95-97 PhD 1995 University of Massachusetts Thrombopoietin-induced genes Science Department Head, Buckingham Browne & Nichols School, Cambridge, MA
Hechler, Beatrice


Post 98-00 PhD





Etablissement Français du Sang-Alsace

Strasbourg, FR.

Overexpression of the P2Y1 receptor specifically in megakaryocytes and platelets from transgenic mice Researcher Group Leader, INSERM,

Strasbourg, France

Pierron, Anne




01 BA Unknown University of Nice,


Effect of adenosine analogs on cell growth Research Associate,

University of Nice, France

Jones, Matthew* P


Pre P 99-03 BA 1996


University of Delaware Regulation of ploidy in vascular smooth muscle and megakaryocytes Assistant Professor; Director, Molecular Medicine Graduate Program, Boston University Med School
Kaluzhny, Yulia


Pre 96-01 MS 1990 Moscow State Institute, Moscow, USSR Lineage determination and apoptosis of megakaryocytes Group Leader, MatTek Corp., Ashland, MA
Lu, Jun*


Pre 97-03 MSc 1996 Nanjing University, Nanjing, P.R. China Nucleosome assembly proteins in hematopoiesis Associate

Professor, Yale School of Medicine

Wang, Zenhngyu (Zack) *


Pre 94-98 BS 1990 East China University of Chem. Technology


Transcriptional regulation of cyclin D3 in megakaryocytes; implication for cell maturation and platelet production Associate Professor of Medicine, Johns Hopkins Medical School; Principal Investigator and ES Cell Core Director,

Center for Molecular Medicine

Maine Medical Center Research Institute (until 2012)

Yaar, Ron




98-02 BSc 1996 Boston University


Regulation of expression of the A3 adenosine receptor in the vasculature Assistant Professor, Director of Resident and International Dermatopathology Training
Dermato-pathology, Boston Medical Center (until 2012); Pathologist, Atlanta
Zhang, Ying*


Pre 98-03 MSc 1988 Univ. Science & Technol, Hefei, China, BSC, 1979, Shanghai Inst. of Biochemistry Mechanism of thrombopoietin effect on platelet development CEO of a Biotech start up in China (former Instructor of Medicine, Boston University, Med)
Dharmaraj, Chinnapen


Post 99-00 PhD 1994 All India Institute of Medical Sciences, New Delhi, India Regulation of polyploidy during hematopoiesis Senior Researcher, Florida Cancer Specialists and Research Institute, Fort Myers, Florida (since 2017); Research Scientist, Astrazeneca, Westborough, MA
Nguyen, Hao*




01-05 BA 1999 Univ. of Cal. Berkely The regulation of Aurora-kinase stability and its role in polyploidization and transformation Assistant Professor of Urology, UCSF, CA; formerly Clinical Fellow, (Resident in Surgery until 2014), Univ. California Davis Medical Center
Yu, Guangyao


Pos 00-02 MD, PhD 1997 Henan Medical University, Zhengzhou, Henan, China (MD; Tongji Medical University, China (PhD) Control of megakaryocyte ploidy and apoptosis Research Scientist, Tetralogic Pharmaceuticals, Malvern, PA


St.Hilaire, Cynthia*


Pre 04-08 BS 2001 Univ. of Vermont Adenosine receptor function in the vasculature Assistant Professor of Cardiology, University of Pittsburgh

(Postdoctoral Fellow, NHLBI till 2015)

McCrann, Donald Jr. *


Pre P 04-08 BS 2001 Yale University Polyploidy and vascular function Research Group Leader, IDEXX Laboratories, Westbrook, ME (Postdoctoral Fellow, Maine Medical Research Center (until 2011)
Liu, Kenian


Post 05-06 PhD 2002 Univ. of Arkansas

Med Sci,

Hematopoiesis and ploidy regulation Member & Assistant Professor, Moffitt Cancer Center &University of South Florida (prior: Researcher, UMDNJ, Center for Human and Molecular Genetics, Newark, NJ)
Makitalo, Maria



(MA courses)

05-07 MA 2004 Sweden Transcriptional signatures in lineage restricted genes PhD researcher, Sweden
Rier, Andrea L


Undergraduate Summer 05 BS 2006 Virginia University Adenosine analogs and cell cycle inhibition Practicing Family Medicine, (trained at Lancaster General Hospital, Lancaster, PA)
Yang, Dan










San Yat-Sen and Hunan Univ., China The role of A2b adenosine receptors in inflammation and vascular pathology Staff Scientist, NHLBI
Papadantonakis, Nicholas


Pre 07-10 MD 2006 University of Crete Regulation of polyploidy in bone marrow cells Assistant Professor; Formerly Hem/Onc Fellow, Cleveland Clinic (before that: MD Resident, Internal Medicine, Jacobi Medical Center/Albert Einstein College of Medicine)
Burridge, Kelley Post 2010 PhD 2007 Boston University Oxidative Stress and megakaryocyte polyploidy Investigator, FDA
Eliades, Alexia*


Pre 07-11 BA 2005 University of Athens Greece Bone marrow megakarypoiesis Research Associate,

University of Manchester, England

Chen, Hongjie


Post 07-11 PhD 2000 Chinese Academy of Sciences The role of adenosine receptors is angiogenesis Assistant Director, Clinical Genetics, Mt. Sinai Medical School, NY
Koupenova-Zamor, Milka*



Then Post

05-10 (Pre); 10-11 (post) BS 2003 Univ. of Cal.

Los Angeles

The role of A2b adenosine receptors in vascular proliferation Instructor of Medicine, University of Mass Medical School
Bhupatiraju, Ajoy V Post 10-present PhD 2006 India Tech Inst Oxidase control of megakaryo-poiesis Teacher, India
Johnston-Cox, Hlillary*


Pre (MD/PhD) 09-14 BS 2007 Univ. of Cal. San Diego The role of A2b adenosine receptors in vascular disease Cardiology Fellow, U Penn; Formerly MD resident, Mt. Sinai Medical School, NY
Carroll, Shannon*


Pre 09-13 BS, MA 2004,


University of Arizona Adenosine receptors and stem cell niche Postdoctoral Fellow, Harvard Medical School
Eisenstein, Anna* Pre (MD/PhD) 10-14 BA 2008 Middlebury College Adenosine receptors and mesenchymal stem cell differentiation Medical Resident, Yale School of Medicine
Mi, Rongjuan Post 12-15 PhD 12/2008 Clemson University,  Clemson, South Carolina


Control of BM matrix by megakaryocyte LOX


Research Scientist, BU Dental School
Patterson, Shenia Pre (MD/PhD) 12-


BS 2010 Spelman College, Atlanta Molecular mechanisms of effects of adenosine on vascular tone Medical Student, BUSM
Lieva, Orly Medical Student 2016-


BS 2013 Wright State University, Magna Cum Laude Control of Bone marrow cell stem-induced myelofibrosis Medical Resident, Harvard Med School and BWH; 2016 Alpha Omega Alpha Carolyn L. Kuckein Student Research Fellowship;

2016 ASH Hematology Opportunities for the Next-Generation of Research Scientists (HONORS) Award

Ng, Seng Kah Post Doc 2016-2018 PhD 2010 Temasek Life Science Laboratory / National University of Singapore


Mechanosensing and megakaryocyte properties Research; San Francisco
Walker, Joshua Post Doc 2016-present PhD 2016 Boston College LOX and uremic solutes control of thrombosis In Dr. Chitalia’s lab collaboratively with Dr. Ravid
Lucero, Hector Research Associate 14-present (part time) PhD 1990 University of Buenos Aires Argentina Control of Bone marrow  matrix by megakaryocyte LOX


In Dr. Ravid’s lab (part time)
Matsuura, Shinobu Post 11-16 Post Doc;


DVM, PhD 2006 DVM: Universidade de Sao Paulo;
PhD: University of Tokyo
Megakaryocyte adhesion properties and significance for myelofibrosis Instructor of Medicine, BU School of Medicine;

In Dr. Ravid’s lab

Ward, Christina Post 2018- PhD 2016 Augusta University Matrix Mechanosensing by megakaryocytes In Dr. Ravid’s lab
Thompson, Cristal Post 2018- PhD 2018 University of Notre Dame Primary myelofibrosis and thrombosis In Dr. Ravid’s lab
Karagianni, Katerina


Pre (PhD) 2018- MS 2018 University of Crete, Greece Megakaryocyte specific KO of LOX- implications for bone and PMF In Dr. Ravid’s lab

(*) Award Recipients


Students from Greece in Dr. Ravid’s lab

Starting in 2012

Student Number: Name: Summer spent in lab: School attended in Greece: Email address:


Alexandra Koutsolelou

summer of 2012

University of Athens, Biology


Efstratios Kofopoulos – Lymperis

summer of 2012

University of Crete, Medicine


Emmanouela Tsagkaraki

summer of 2013

University of Crete, Medicine


Michail Kontakis

summer of 2013

University of Crete, Medicine


George Kalarakis

summer of 2014

University of Crete, Medicine


Eleni Terezaki

summer of 2014

University of Crete, Medicine