Research Projects

FTMS Instrumentation Development

Electron-Activated Dissociation (ExD) of Glycans

Theoretical Investigation of the Glycan ExD Mechanism

High Throughput MALDI-FTMS

High Pressure MALDI on FTMS

Cryogenic FTMS

Improved Electrospray Ion Source for FTMS

Improved FTMS data analysis and data mining routines

Fundamentals

Correlation of solution phase protein free radical chemistry with gas phase protein free radicals generated from electron capture dissociation.

Applications

Use of Electron Capture Dissociation for the analysis of novel protein sidechains

Use of electrospray Fourier Transform Mass Spectrometry for the localization of sidechain modifications in Aldolase.

Primary teaching affiliate
of BU School of Medicine