Study: Why people with knee osteoarthritis experience different kinds of pain

Osteoarthritis is the most common form of arthritis worldwide, affecting more than 300 million people. It causes substantial pain, functional limitations, and disability in patients.

“Our findings support the clinical relevance of neurobiological mechanisms that affect the pain experience in knee osteoarthritis, including not only the severity of pain, but whether the pain is intermittent or constant, and whether the pain is unpredictable,” said senior author Tuhina Neogi, MD, Ph.D., professor of medicine and epidemiology at Boston University School of Medicine.

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The Association of Pain Sensitization and Conditioned Pain Modulation to Pain Patterns in Knee Osteoarthritis

First published: 03 September 2020