November 16, 2018 BU Pharmacology-Biogen Symposium: Innovations in Neuroscience Discovery
Innovations in Neuroscience Drug Discovery
Friday, November 16th 2018, 8:00 a.m. – 6:30 p.m.
BU Pharmacology & Experimental Therapeutics – Biogen Symposium
Biogen, 300 Binney Street, Cambridge, MA 02142
Free and open to the public.
REGISTRATION
Registration has now closed. There is no onsite registration.
BU-Biogen Symposium booklet_20181107_230pm
Registration and Breakfast
David H. Farb, Ph.D., Boston University: Academia-Industry Alliances: Catalyzing Discovery Science
Anabella Villalobos, Ph.D., Biogen: Biogen Opening Remarks
Session 1: Harnessing Cutting-Edge Technology to Enable Drug Discovery
Georgios Skiniotis, Ph.D., Stanford University: CryoEM Insights into GPCR Activation and Signaling
Anthony W. P. Fitzpatrick, Ph.D., Columbia University: Untangling Neurodegenerative Diseases Using Patient-Based Structural Biology
Shelley J. Russek, Ph.D., Boston University: JAK/STATs and the Brain: a Pharmacological Window on the BDNF Transcriptome of Neurological Disease
Hongkui Zeng, Ph.D., Allen Institute for Brain Science: Cell Type Classification and Circuit Mapping in the Brain: Mapping a Path to Discovery
Xue Han, Ph.D., Boston University: Optical Analysis of Biological Neural Networks Across Scales
Session 2: Neuroinflammation at the Nexus of CNS Diseases
Anirvan Ghosh, Ph.D., Biogen: Introductory Remarks
Staci Bilbo, Ph.D., MGH/Harvard Medical School: Neuroimmune Interactions in Development: Implications for Health Throughout the Lifespan
Dorothy P. Schafer, Ph.D., UMASS Medical Center: Microglial Phagocytic Mechanisms Governing Brain Plasticity in Health and Disease
Tsuneya Ikezu, M.D., Ph.D., Boston University: Proteomic and Neuropathological Characterization of Extracellular Vesicles in Alzheimer’s Disease
Benjamin Wolozin, M.D., Ph.D., Boston University: Membrane-Less Organelles and RNA Binding Proteins as Targets for Therapy of Neurodegenerative Diseases
Session 3: Pharmacology, Models and Biomarkers: Bench to Bedside
Leonard Petrucelli, Ph.D., Mayo Clinic-Jacksonville: Therapeutic Insights into Repeat Expansion Disorders
Wendy Qiu, M.D., Ph.D., Boston University: Alzheimer’s Disease: The Brain Disease or the Peripheral System-Brain Axis Disease?
Thomas Kornecook, Ph.D., Biogen: Animal Models in Neuroscience Drug Discovery: The Good, the Bad, and the Ugly
Himanshu Naik, Ph.D., Biogen: Application of Pharmacokinetic and Pharmacodynamic Modeling in Drug Development
Closing Remarks
Reception