Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are complex syndromes with three overlapping phases characterized by the reduction of pulmonary compliance, disruption of the epithelial and endothelial barrier, and recruitment of inflammatory cells into the alveoli. However, how lung cells communicate with each other remains unclear. This work uncovers a novel mechanism […]
Congratulations to Professor Jay Mizgerd for renewing his R01 award from the NIH titled “Lung-resident antibacterial heterotypic immunity.” The new award is for 5 years, through June 2024, and will be used to discover mechanisms that localize and instruct the memory T cells in the lung tissue that provide effective protection against pneumonia.
Dr. Korkmaz, can you please tell us about the new award you received? My work studying the acute response to lower respiratory infection was recently funded as an F32 postdoctoral fellowship by the National Heart, Lung and Blood Institute at the NIH. This provides me the opportunity to delve into the previously unknown role of […]
This work demonstrated that B cells, which typically protect us against infection, function abnormally and promote interstitial lung disease in patients with common variable immunodeficiency (CVID). CVID is a primary immunodeficiency, a type of disorder where individuals have an immune system that does not function properly – causing infections and, for reasons not understood, also […]
Congratulations to PhD student Emad Arafa in Professor Jay Mizgerd’s group for receiving an F31 award from the NIH on “Pneumonia and alveolar macrophage resilience”
On February 1, 2019, Paul J. (PJ) Maglione, MD, PhD, joined the Pulmonary Center as Assistant Professor in the Section of Pulmonary, Allergy, Critical Care and Sleep Medicine What is your educational background? I attended elementary through high school in the Hudson Valley of New York near Peekskill, about a 45 minute train ride from Manhattan. […]