BU Researchers Describe Rebuilding, Regenerating Lung Cells

This week, Pulmonary Center researchers from the Center for Regenerative Medicine (CReM) report their successes in developing new techniques to implant engineered cells into damaged lung tissue. Such breakthroughs could offer potential treatments for lung conditions like emphysema, pulmonary fibrosis, and COVID-19. The studies, which outline the process of engineering lung stem cells and introducing […]

Podcast episode featuring Fellow Dr. Lauren Kearney

Dr. Lauren Kearney, third year pulmonary fellow, was joined by Dr. Katie Steiling and Dr. Chris Reardon to discuss an interesting case, highlight our pulmonary fellowship program, and share some research efforts to improve health equity. They were featured in an episode of Pulm PEEPs, from their Fellows’ Case Files series. The hosts, Drs. Kristina […]

New RO1: Molecular Pathomechanisms of Legionellosis

In late June, we were delighted to learn that Dr. Markus Bosmann received funding for his new R01 ‘Molecular Pathomechanisms of Legionellosis’. Over the next four years, Dr. Bosmann will use this grant to study Legionella. Legionella are facultative, intracellular bacteria residing in aquatic environments from which contaminated inhaled aerosols cause accidental infections leading to […]

Interview with Nicholas Bosch MD, MSc

  In this interview, Nicholas Bosch, MD goes into depth about his recent study and subsequent publication. Nicholas Bosch MD, MSc Assistant Professor, Pulmonary, Allergy, Sleep & Critical Care Medicine   Bosch NA, Teja B, Law AC, Pang B, Jafarzadeh SR, Walkey AJ. Comparative Effectiveness of Fludrocortisone and Hydrocortisone vs Hydrocortisone Alone Among Patients With […]

2023 Kayla Bell Citizen Award Winner

The Pulmonary Center is happy to announce Mary Lou Beermann as the winner of the 2023 Kayla Bell Pulmonary Center Citizenship Award! Mary Lou Beermann Lab Manager, BU Center for Regenerative Medicine (CReM)   Mary Lou was selected as this year’s recipient of the award for their exceptional contributions to our research community. Their kindness, […]

Trainee Triumphs

Several of our current or recent trainees have received exciting news. Congratulations to the following for these fellowship or faculty transition awards:   “Microbial Dysbiosis and Epithelial Dysfunction in Vitamin A-deficient Lungs” F31 Predoctoral Fellowship, NIH Date of Award: 2/20/2023   Kiloni Quiles-Franco PhD Candidate – Molecular and Translational Medicine Pulmonary Center and Section of […]

Jerome S. Brody, MD

Our Pulmonary Center community is heartbroken by the loss of Jerry Brody, who passed away peacefully on January 22, 2023, at his home in Boston while surrounded by family, after a brave battle against Alzheimer’s disease. He was 88 years old. Jerry meant so much to us here at BU and in the Pulmonary Center. […]

CRISPR interference interrogation of COPD GWAS genes

This project developed to address limitations in our understanding of the genetic factors that predispose a subset of individuals exposed to environmental injury to develop COPD, a major contributor to morbidity and mortality worldwide. While genome-wide association studies (GWAS) have now identified 82 variants across the genome as significantly associated with risk of developing COPD, […]

A Multimodal iPSC Platform for Cystic Fibrosis Drug Testing

In 2022, the major challenge in cystic fibrosis is developing treatments for individuals who do not respond to highly effective modulator therapy. These individuals have mutations that lead to no residual CFTR protein. In vitro models have a proven track record in developing effective treatments for CF patients however access to cells from these high […]

New R01: Biology of Lymphangiogenesis in the Adult Lung

In June, we were delighted to learn that our new R01 entitled Biology of Lymphangiogenesis in the Adult Lung was funded. This work builds upon exciting data generated by Senegal Carty (PiBS graduate student) and Erin Crossey MD, PhD (pulmonary fellow; Figure 1) demonstrating that robust lymphangiogenesis (Figure 2) and changes in lymphatic cell phenotype […]