Karen M. Harnett, PhD

Assistant Professor, Pharmacology & Experimental Therapeutics

(617) 414-2653
72 E. Concord St Instructional (L)

Education

  • Boston University School of Medicine, PhD
  • Providence College, BS

Classes Taught

  • GMS PM 802
  • MD530
  • second year medical

Publications

  • Published on 1/28/2014

    Rieder F, Nonevski I, Ma J, Ouyang Z, West G, Protheroe C, DePetris G, Schirbel A, Lapinski J, Goldblum J, Bonfield T, Lopez R, Harnett K, Lee J, Hirano I, Falk G, Biancani P, Fiocchi C. T-helper 2 cytokines, transforming growth factor ß1, and eosinophil products induce fibrogenesis and alter muscle motility in patients with eosinophilic esophagitis. Gastroenterology. 2014 May; 146(5):1266-77.e1-9. PMID: 24486052.

    Read at: PubMed
  • Published on 7/12/2012

    Ma J, Altomare A, Guarino M, Cicala M, Rieder F, Fiocchi C, Li D, Cao W, Behar J, Biancani P, Harnett KM. HCl-induced and ATP-dependent upregulation of TRPV1 receptor expression and cytokine production by human esophageal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1; 303(5):G635-45. PMID: 22790593.

    Read at: PubMed
  • Published on 6/26/2012

    Altomare A, Ma J, Guarino MP, Cheng L, Rieder F, Ribolsi M, Fiocchi C, Biancani P, Harnett K, Cicala M. Platelet-activating factor and distinct chemokines are elevated in mucosal biopsies of erosive compared with non-erosive reflux disease patients and controls. Neurogastroenterol Motil. 2012 Oct; 24(10):943-e463. PMID: 22734465.

    Read at: PubMed
  • Published on 9/29/2011

    Ma J, Altomare A, Rieder F, Behar J, Biancani P, Harnett KM. ATP: a mediator for HCl-induced TRPV1 activation in esophageal mucosa. Am J Physiol Gastrointest Liver Physiol. 2011 Dec; 301(6):G1075-82. PMID: 21960521.

    Read at: PubMed
  • Published on 9/1/2011

    Orlando RC, Paterson WG, Harnett KM, Ma J, Behar J, Biancani P, Guarino MP, Altomare A, Cicala M, Cao W. Esophageal disease: updated information on inflammation. Ann N Y Acad Sci. 2011 Sep; 1232:369-75. PMID: 21950828.

    Read at: PubMed
  • Published on 10/30/2010

    Harnett KM, Rieder F, Behar J, Biancani P. Viewpoints on Acid-induced inflammatory mediators in esophageal mucosa. J Neurogastroenterol Motil. 2010 Oct; 16(4):374-88. PMID: 21103419.

    Read at: PubMed
  • Published on 7/8/2010

    Ma J, Altomare A, de la Monte S, Tong M, Rieder F, Fiocchi C, Behar J, Shindou H, Biancani P, Harnett KM. HCl-induced inflammatory mediators in esophageal mucosa increase migration and production of H2O2 by peripheral blood leukocytes. Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3):G791-8. PMID: 20616304.

    Read at: PubMed
  • Published on 5/6/2010

    Guarino MP, Cheng L, Ma J, Harnett K, Biancani P, Altomare A, Panzera F, Behar J, Cicala M. Increased TRPV1 gene expression in esophageal mucosa of patients with non-erosive and erosive reflux disease. Neurogastroenterol Motil. 2010 Jul; 22(7):746-51, e219. PMID: 20456759.

    Read at: PubMed
  • Published on 3/18/2010

    Rieder F, Biancani P, Harnett K, Yerian L, Falk GW. Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, and carcinogenesis. Am J Physiol Gastrointest Liver Physiol. 2010 May; 298(5):G571-81. PMID: 20299604.

    Read at: PubMed
  • Published on 12/3/2009

    Ma J, Harnett KM, Behar J, Biancani P, Cao W. Signaling in TRPV1-induced platelet activating factor (PAF) in human esophageal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2010 Feb; 298(2):G233-40. PMID: 19959817.

    Read at: PubMed

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