Publications
2019
2018
- Majid S, Keith RJ, Fetterman JL, Weisbrod RM, Nystoriak J, Wilson T, Stokes AC, Blaha MJ, Srivastava S, Robertson RM, Bhatnagar A, Hamburg NM. Lipid profiles in users of combustible and electronic cigarettes. Vasc Med. 2021 Oct;26(5):483-488. doi: 10.1177/1358863X211009313. Epub 2021 May 20. PMID: 34013801.
- Matsuura S, Thompson CR, Ng SK, Ward CM, Karagianni A, Mazzeo C, Malara A, Balduini A, Ravid K. Adhesion to fibronectin via α5β1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis. Blood. 2020 Jun 18;135(25):2286-2291. doi: 10.1182/blood.2019004230. PMID: 32294178; PMCID: PMC7316217.
- Sponholtz TR, Palmer JR, Rosenberg LA, Hatch EE, Adams-Campbell LL, Wise LA. Exogenous Hormone Use and Endometrial Cancer in U.S. Black Women. Cancer Epidemiol Biomarkers Prev. 2018 May;27(5):558-565. doi: 10.1158/1055-9965.EPI-17-0722. Epub 2018 Feb 23. PMID: 29475971; PMCID: PMC5991910.
- Sponholtz TR, Vasan RS. Contribution of the neighborhood environment to cross-sectional variation in long-term CVD risk scores in the Framingham Heart Study. PLoS One. 2018 Aug 6;13(8):e0201712. doi: 10.1371/journal.pone.0201712. PMID: 30080891; PMCID: PMC6078286.
- Warr N, May J, Teboul L, Suzuki T, Asami M, Perry ACF, Wells S, Greenfield A. Characterisation and use of a functional Gadd45g bacterial artificial chromosome. Sci Rep. 2018 Nov 23;8(1):17318. doi: 10.1038/s41598-018-35458-5. PMID: 30470800; PMCID: PMC6251886.
2017
- Chavkin NW, Walsh K, Hirschi KK. Isolation of Highly Purified and Viable Retinal Endothelial Cells. J Vasc Res. 2021;58(1):49-57. doi: 10.1159/000510533. Epub 2020 Oct 6. PMID: 33022674; PMCID: PMC7850292.
- Chavkin NW, Sano S, Wang Y, Oshima K, Ogawa H, Horitani K, Sano M, MacLauchlan S, Nelson A, Setia K, Vippa T, Watanabe Y, Saucerman JJ, Hirschi KK, Gokce N, Walsh K. The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation. J Am Heart Assoc. 2021 Jul 6;10(13):e019904. doi: 10.1161/JAHA.120.019904. Epub 2021 Jun 22. PMID: 34155901; PMCID: PMC8403294.
- Chavkin NW, Min KD, Walsh K. Importance of clonal hematopoiesis in heart failure. Trends Cardiovasc Med. 2022 May;32(4):198-203. doi: 10.1016/j.tcm.2021.04.005. Epub 2021 Apr 20. PMID: 33892102; PMCID: PMC8526615.
- Chavkin NW, Cain S, Walsh K, Hirschi KK. Isolation of Murine Retinal Endothelial Cells for Next-Generation Sequencing. J Vis Exp. 2021 Oct 11;(176):10.3791/63133. doi: 10.3791/63133. PMID: 34694293; PMCID: PMC8641104.
- Ritter RC, Campos CA, Nasse J, Peters JH. Vagal Afferent Signaling and the Integration of Direct and Indirect Controls of Food Intake. In: Harris RBS, editor. Appetite and Food Intake: Central Control. 2nd ed. Boca Raton (FL): CRC Press/Taylor & Francis; 2017. Chapter 11. PMID: 28880508.
2016
- Walker JA, Richards S, Whelan SA, Yoo SB, Russell TL, Arinze N, Lotfollahzadeh S, Napoleon MA, Belghasem M, Lee N, Dember LM, Ravid K, Chitalia VC. Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKD. J Am Soc Nephrol. 2021 Nov;32(11):2834-2850. doi: 10.1681/ASN.2020091310. PMID: 34716244; PMCID: PMC8806102.
- Taylor EN, Huang N, Wisco J, Wang Y, Morgan KG, Hamilton JA. The brains of aged mice are characterized by altered tissue diffusion properties and cerebral microbleeds. J Transl Med. 2020 Jul 8;18(1):277. doi: 10.1186/s12967-020-02441-6. PMID: 32641073; PMCID: PMC7346388.
- Maruyama S, Wu CL, Yoshida S, Zhang D, Li PH, Wu F, Parker Duffen J, Yao R, Jardin B, Adham IM, Law R, Berger J, Di Marchi R, Walsh K. Relaxin Family Member Insulin-Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models. J Am Heart Assoc. 2018 Jun 10;7(12):e008441. doi: 10.1161/JAHA.117.008441. PMID: 29887522; PMCID: PMC6220528.
2015
- Akintewe OO, Roberts EG, Rim NG, Ferguson MAH, Wong JY. Design Approaches to Myocardial and Vascular Tissue Engineering. Annu Rev Biomed Eng. 2017 Jun 21;19:389-414. doi: 10.1146/annurev-bioeng-071516-044641. Epub 2017 May 3. PMID: 28471698.
- Gopal DM, Ayalon N, Wang YC, Siwik D, Sverdlov A, Donohue C, Perez A, Downing J, Apovian C, Silva V, Panagia M, Kolachalama V, Ho JE, Liang CS, Gokce N, Colucci WS. Galectin-3 Is Associated With Stage B Metabolic Heart Disease and Pulmonary Hypertension in Young Obese Patients. J Am Heart Assoc. 2019 Apr 2;8(7):e011100. doi: 10.1161/JAHA.118.011100. PMID: 30929550; PMCID: PMC6509711.
2014
- Hylek EM, Ko D, Cove CL. Gaps in translation from trials to practice: non-vitamin K antagonist oral anticoagulants (NOACs) for stroke prevention in atrial fibrillation. Thromb Haemost. 2014 May 5;111(5):783-8. doi: 10.1160/TH13-12-1032. Epub 2014 Feb 27. PMID: 24573511.
- Gokce N, Karki S, Dobyns A, Zizza E, Sroczynski E, Palmisano JN, Mazzotta C, Hamburg NM, Pernar LI, Carmine B, Carter CO, LaValley M, Hess DT, Apovian CM, Farb MG. Association of Bariatric Surgery With Vascular Outcomes. JAMA Netw Open. 2021 Jul 1;4(7):e2115267. doi: 10.1001/jamanetworkopen.2021.15267. PMID: 34251443; PMCID: PMC8276087.
- Ronald L Neppl, Chia-Ling Wu, Kenneth Walsh; lncRNA Chronos is an aging-induced inhibitor of muscle hypertrophy. J Cell Biol 6 November 2017; 216 (11): 3497–3507. doi: https://doi.org/10.1083/jcb.201612100
2013
- Rosenquist KJ, Massaro JM, Pencina KM, D’Agostino RB, Beiser A, O’Connor GT, O’Donnell CJ, Wolf PA, Polak JF, Seshadri S, Fox CS Neck circumference, carotid wall intima-media thickness, and incident stroke. Diabetes Care. 2013 Sep;36(9):e153-4. doi: 10.2337/dc13-0379.PMID:23970728 PubMed – in process]
- Rosenquist KJ, Pedley A, Massaro JM, Therkelsen KE, Murabito JM, Hoffmann U, Fox CS. Visceral and subcutaneous fat quality and cardiometabolic risk. JACC Cardiovasc Imaging. 2013 Jul;6(7):762-71. doi: 10.1016/j.jcmg.2012.11.021. Epub 2013 May 8. PMID: 23664720 [PubMed – in process]
- Koupenova M, Ravid K Adenosine, adenosine receptors and their role in glucose homeostasis and lipid metabolism. J Cell Physiol. 2013 Mar 4. doi: 10.1002/jcp.24352. [Epub ahead of print]
- Steen DL, Cannon CP, Lele SS, Rajapurkar MM, Mukhopadhyay B, Scirica BM, Murphy SA, Morrow DA. Prognostic evaluation of catalytic iron in patients with acute coronary syndromes. Clin Cardiol. 2013 Mar;36(3):139-45. doi: 10.1002/clc.22089. Epub 2013 Feb 3.
2012
- Johnston-Cox H*, Koupenova M*[*equal contribution], Yang D, Corkey B, Gokce N, Farb MG, LeBrasseur N, Ravid K. The A2b adenosine receptor modulates glucose homeostasis and obesity. PLoS One. 2012;7(7):e40584. Epub 2012 Jul 25. PMID:22848385
- Johnston-Cox HA, Koupenova M, Ravid K. A2 adenosine receptors and vascular pathologies. Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):870-8. PMID:22423039
- Ngoh, G. A., Papanicolaou, K. N., and Walsh, K. Loss of mitofusin 2 promotes endoplasmic reticulum stress. J Biol Chem. 2012, 287(24):20321-20332 (PMC3370214).
- Papanicolaou, K. N., Ngoh, G. A., Dabkowski, E. R., O’Connell, K. A., Ribeiro, R. F., Stanley, W. C., Walsh, K. Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death. Am J Physiol Heart Circ Physiol. 2011, 302(1):H167-H179 (PMC3334239).
- Risitano A, Beaulieu LM, Vitseva O, Freedman JE. Platelets and platelet-like particles mediate intercellular RNA transfer. Blood. 2012 Jun 28;119(26):6288-95. PMID: 22596260
- Steen DL, Cannon, CP. Atherosclerosis: Effects of evacetrapib administered as monotherapy or in combination with statins. Reviews in Cardiovascular Medicine. 2012: 13(1): e48-51
- Steen DL, Wiviott SD, Cannon CP. February 17, 2012. HDL and CETP Inhibition. Last Accessed February 22, 2012. http://www.cardiosource.org/Science-And-Quality/Expert-Opinions-and-Cases/Hot-Topics/2012/02/HDL-and-CETP-Inhibition.aspx.
- Papanicolaou K. N., Kikuchi R., Ngoh G. A., Coughlan K. A., Dominguez I., Stanley W. C., Walsh K. Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. Circ Res. 2012, 111(8):1012-1026 (PMC in process).
- Koupenova M, Johnston-Cox H, Vezeridis A, Gavras H, Yang D, Zannis V, Ravid K. A2b adenosine receptor regulates hyperlipidemia and atherosclerosis. Circulation. 2012 Jan 17;125(2):354-63. Epub 2011 Dec 5. PMID:22144568
- Koupenova M, Johnston-Cox H, Ravid K. Regulation of atherosclerosis and associated risk factors by adenosine and adenosine receptors. Curr Atheroscler Rep. 2012 Oct;14(5):460-8.PMID: 22850979
- Xu XJ, Gauthier MS, Hess DT, Apovian CM, Cacicedo JM, Gokce N, Farb M, Valentine RJ, Ruderman NB. Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue. J Lipid Res. 2012; 53(4):792-801.
- Nelson LE, Valentine RJ, Cacicedo JM, Gauthier MS, Ido Y, Ruderman NB. A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose exposed HepG2 cells. Am J Physiol Cell Physiol. 2012; 303(1):C4-C13.
2011
- Farb MG, Bigornia S, Mott M, Tanriverdi K, Morin KM, Freedman JE, Joseph L, Hess DT, Apovian CM, Vita JA, Gokce N. Reduced adipose tissue inflammation represents an intermediate cardiometabolic phenotype in obesity. J Am Coll Cardiol. 2011 Jul 12;58(3):232-7. PMID: 21737012
- Farb MG, Ganley-Leal L, Mott M, Liang Y, Ercan B, Widlansky ME, Bigornia SJ, Fiscale AJ, Apovian CM, Carmine B, Hess DT, Vita JA, Gokce N. Arteriolar Function in Visceral Adipose Tissue Is Impaired in Human Obesity. Arterioscler Thromb Vasc Biol. 2011 Nov 17. [Epub ahead of print] PMID: 22095978
- Papanicolaou KN, Ngoh GA, Dabkowski ER, O’Connell KA, Ribeiro RF, Stanley WC, Walsh K. Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death. Am J Physiol Heart Circ Physiol. 2011 Oct 28. PMID: 22037195
- Koupenova M, Johnston-Cox H, Vezeridis A, Gavras H, Yang D, Zannis V, Ravid K A2b adenosine receptor regulates hyperlipidemia and atherosclerosis. Circulation. 2012 Jan 17;125(2):354-63. Epub 2011 Dec 5. PMID:22144568
- Lugus J. J., Ngoh G. A., Bachschmid M. M., Walsh K. Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells. J Mol Cell Cardiol. 2011, 51(6):885-893 (PMC3208756). Accompanied by editorial.
- Papanicolaou K N. ,Khairallah R J., Ngoh G. A., Chikando A., Luptak I., O’Shea K M., Riley D D., Lugus J J., Colucci W S., Lederer W J., Stanley W C., Walsh K. Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Mol. Cell. Biol. 2011, 31:1309–1328 (PMC3067905).
2010
2009
- Blair, PS, S Rex, O Vitseva, L Beaulieu, K Tanriverdi, S Chakrabarti, C Hayashi, CA Genco, M Iafrati, JE Freedman. (2009) Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. Circulation Research 104(3):346-54.
- Lin, E, JE Freedman, LM Beaulieu. (2009) Innate Immunity and Toll-like Receptor Antagonists: A Potential Role in the Treatment of Cardiovascular Diseases. Cardiovascular Therapeutics Summer; 27(2):117-23.
- Chakrabarti, S, LM Beaulieu, Reyelt LA, Iafrati MD, Freedman JE. (2009) M118, a novel low-molecular weight heparin with decreased polydispersity leads to enhanced anticoagulant activity and thrombotic occlusion in ApoE knockout mice. J Thromb Thrombolysis. Nov;28(4):394-400.
- Rex, S, LM Beaulieu, DH Perlman, O Vitseva, PS Blair, ME McComb, CE Costello, JE Freedman. (2009) Immune vs. thrombotic stimulation of platelets differentially regulates signaling pathways, intracellular protein-protein interactions, and -granule release. Thromb Haemost Jul; 102(1):97-110.
- MM Dohadwala and JA Vita. Grapes and Cardiovascular Disease. Journal of Nutrition; Vol. 139, No. 9, 1788S-1793S, September 2009.
- Dohadwala, MM, Dellara F. Terry, Noyan Gokce and Joseph A. Vita William B. Chung, Naomi M. Hamburg, Monika Holbrook, Sherene M. Shenouda. Presence of Cardiovascular Risk Factors, The Brachial Artery Remodels to Maintain Local Shear Stress Arterioscler Thromb Vasc Biol 2009;29;606-612.
- Beaulieu LM, Freedman JE. NFkappaB regulation of platelet function: no nucleus, no genes, no problem? J Thromb Haemost. 2009 Aug;7(8):1329-32. doi: 10.1111/j.1538-7836.2009.03505.x. Epub 2009 Jun 3. No abstract available.
2008
- St. Hilaire C., Carroll S.H., Chen H., Ravid K., Mechanisms of induction of adenosine receptor genes and its functional significance. J Cell Physiol. 2008; 218: 35-44.
- Chung WB, Hamburg NM, Shenouda SM, Titas M, Rosen A, Dohadwala M, Holbrook M, Terry DF, Gokce N, Vita JA. The Brachial Artery Remodels Appropriately to Maintain Local Shear Stress Despite the Presence of Obesity and Systemic Atherosclerosis. Circulation 2008; 118:S474 (abstract).
2007
- Beaulieu, LM and FC Church. (2007) Activated Protein C Promotes Breast Cancer Migration Through Interactions with EPCR and PAR-1. Experimental Cell Research 313(4):677-87.
- Beaulieu, LM, BR Whitley, TF Wiesner, D Palmieri, SM Rehault, A Elkahloun, and FC Church. (2007) Breast Cancer and Metabolic Syndrome Linked Through the Plasminogen Activator Inhibitor-1 Cycle. Bioessays 29(10):1029-38.
- Hamburg NM, McMackin CJ, Huang AL, Shenouda SM, Widlansky ME, Schulz E, Gokce N, Ruderman NB, Keaney JF Jr, Vita JA. Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2650-6. Epub 2007 Oct 11.
- Rau, JC, LM Beaulieu, JA Huntington, and FC Church. (2007) Serpins in Haemostasis, Thrombosis, and Fibrinolysis. Journal of Thrombosis and Haemostasis 5 Suppl 1:102-15.
- Shenouda SM, Vita JA. Effects of flavonoid-containing beverages and EGCG on endothelial function. J Am Coll Nutr. 2007 Aug;26(4):366S-372S.
- Smirnov S, Isern NG, Jiang ZG, Hoyt DW, McKnight CJ. “The Isolated Sixth Gelsolin Repeat and Headpiece Domain of Villin Bundle F-Actin in the Presence of Calcium and Are Linked by a 40-Residue Unstructured Sequence”, Biochemistry, 46(25), 7488-7496 , 2007.
- Takemura Y, Ouchi N, Shibata R, Aprahamian T, Kirber MT, Summer RS, Kihara S, Walsh K. (2007) Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. J. Clin. Invest. Feb 1;117(2):375-386
- Whitley, BR, LM Beaulieu, JC Carter, and FC Church. (2007) Phosphatidylinositol 3-Kinase/ Akt Regulates the Balance Between Plasminogen Activator Inhibitor-1 and Urokinase to Promote Migration of SKOV-3 Ovarian Cancer Cells. Gynecologic Oncology 104(2): 470-9.
2006
- Aprahamian T, Bonegio R, Rizzo J, Perlman H, Lefer DJ, Rifkin I, Walsh K (2006). Simvastatin treatment ameliorates autoimmune disease associated with accelerated atherosclerosis in a murine lupus model. J Immunol (Sep 1;177(5):3028-34).
- Kelly M, Ruderman NB, Tomas E. AMP Activated Protein Kinase and its Regulation by Adiponectin and interleukin-6 . Scandinavian Journal of Food and Nutrition. 2006 Dec;50 Suppl 2: 85-91.
- Moussa, C., Fu, Q., Kumar, P., Shtifman, A., Lopez, JR., Allen, PD., Weinberg, D., Magrane, J., Aprahamian, T., Walsh, K., Rosen, K., Querfurth, H. (2006) Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology. FASEB J (Oct;20(12):2165-7)
- Ruderman NB, Keller C, Richard AM, Saha AK, Luo Z, Xiang X, Giralt M, Ritov VB, Kelley DE, Hidalgo J, Pedersen BK, Kelly M. Interleukin-6 regulation of AMPK: Potential Role in the systemic response to exercise and prevention of the metabolic syndrome. Diabetes. 2006 Dec;55 Suppl 2:S48-54.
- Schiekofer S., Galasso, G., Andrassy M., Aprahamian T., Rocnik E., Schneider J. (2006) Glucose control with insulin results in reduction of NF-κB binding activity in mononuclear blood cells of patients with recently manifested type I diabetes. Diabetes, Obesity, and Metabolism (Sep;8(5):473-82)