Jacob Beierle, PhD candidate, published in Molecular Pain
Jacob Beierle, Biomolecular Pharmacology PhD candidate in the Laboratory of Addiction Genetics under the mentorship of Dr. Camron Bryant, published his article, “Genetic basis of thermal nociceptive sensitivity and brain weight in a BALB/c reduced complexity cross”, in Molecular Pain on January 28, 2022.
In order to better understand the genetics of pain, Jacob and his collaborators studied two nearly identical strains of mice (BALB/cJ and BALB/cByJ) by crosses and observed differences in thermal nociception and mechanical stimulation, suggesting that the limited genetic differences between these two substrains was altering pain sensitivity. These data come from a larger study interrogating the genetic structure of Oxycodone related behaviors in the BALB/cJ and BALB/cByJ substrains, making these mice excellent candidates to investigate genetic variation mediating differences in a slew of medically relevant outcomes.
Beierle JA, Yao EJ, Goldstein SI, et al. Genetic basis of thermal nociceptive sensitivity and brain weight in a BALB/c reduced complexity cross. Molecular Pain. 2022 Jan:17448069221079540. DOI: 10.1177/17448069221079540. PMID: 35088629.
