Elyse Olesinski’s research selected for AMA Research Challenge
The American Medical Association Research Challenge is the largest national, multi-specialty
research event for medical students and fellows to share and present their research. Elyse’s research was performed with a medical oncology research team at Dana-Farber Cancer Institute and Harvard Medical School investigating acute myeloid leukemia (AML) pathologies. Specifically, her projects have focused on identifying underlying BCL-2 family protein dependencies and therapies to which tumors are sensitive, using a functional assay called dynamic BH3 profiling, which measures mitochondrial apoptotic signaling.
For the 2022 Research Challenge, Elyse’s abstract: “Targeting reduced mitochondrial apoptotic signaling in relapsed acute myeloid leukemia” was selected as a semi-finalist for the event, and Elyse will present her research at their poster symposium in October. This project has the goal of evaluating emerging mechanisms of resistance against targeted therapies and to identify potential strategies overcoming resistance in AML.