Marianne Collard, Ph.D.

Summary

Dr. Collard is interested in understanding how nutrition and metabolism influence melanoma development, progression, and resistance to therapy. She aims to leverage metabolic perturbations in melanoma to develop better diagnostic tools and treatments. Dr. Collard has a particular focus on teaching and mentoring trainees.

Education

2011-2015   B.S. Cornell University, Ithaca, NY; Cum Laude, Bioengineering

2015-2019   Ph.D. Wake Forest University, Winston-Salem, NC; Integrative Physiology and Pharmacology

2019-2021   Postdoctoral Research Fellow, Boston University, Boston, MA

Research Interests

• Cancer Biology
• Nutrition and Metabolism
• Epigenetics
• Gut Microbiome
• Natural Products

Publications

Wu M., Hanly, A., Gibson, F., Kuang, K., Kalin, J., Nocco, S., Collard, M., Cole, M., Xiao, A., Agus, F., Labadorf, A., Cole, P.A., Alani, R.M. (2021) The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma. (In preparation). https://www.biorxiv.org/content/10.1101/2020.09.30.320580v1

Gibson, F., Hanly, A., Collard, M., Grbic, N., Grunberg, N., Alani, R., Wu, M. (2021) Targeting Epigenetic Players in Autoimmune and Inflammatory Skin Disease. (In preparation).

Collard, M., Austin, N., Brown-Harding, H., Westwood, B., Gallagher, P. E., & Tallant, A. (2021). Muscadine Grape Extract Reduces Triple Negative Breast Cancer Metastasis and Alters the Gut Microbiome in a 4T1 Metastatic Mouse Model. (Submitted)

Lee, H. J., Chen, Z., Collard, M., Chen, F., Chen, J. G., Wu, M., . . . Cheng, J.-X. (2021). Multimodal Metabolic Imaging Reveals Pigment Reduction and Lipid Accumulation in Metastatic Melanoma. BME Frontiers, 2021, 9860123. https://doi.org/10.34133/2021/9860123

Kam, S., Collard, M., Lam, J., & Alani, R. M. (2021). Gut Microbiome Perturbations in Patients with Hidradenitis Suppurativa: A Case Series. J Invest Dermatol, 141(1), 225-228.e222. https://doi.org/10.1016/j.jid.2020.04.017

Collard, M., Gallagher, P. E., & Tallant, E. A. (2020). A Polyphenol-Rich Extract From Muscadine Grapes Inhibits Triple-Negative Breast Tumor Growth. Integrative cancer therapies, 19, 1534735420917444-1534735420917444. https://doi.org/10.1177/1534735420917444