Gerald V. Denis, PhD, Named Shipley Prostate Cancer Research Professor

Gerald V. Denis, PhD, has been named the Shipley Prostate Cancer Research Professor effective September 1, and will represent the molecular oncology themes of the Center. Dr. Denis has been a member of the BU faculty for 23 years, during which time he pioneered studies of the Bromodomain and ExtraTerminal (BET) protein family that is […]

BU and Johnson & Johnson Innovation Team Up to Fight Lung Cancer

Tuesday, June 6, 2018 Written by: Sara Rimer and Art Jahnke | Source: BUToday New Medical Campus center hopes to speed development of interventions and cures In what Boston University President Robert A. Brown envisions as a model for industry and academia collaborating to improve human health, BU has launched a five-year translational research alliance with Johnson & […]

BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-Mesenchymal Transition

Published April 2018 Provided by: American Association for Cancer Research Publications | Source: Molecular Cancer Research Guillaume P. Andrieu and Gerald V. Denis DOI: 10.1158/1541-7786.MCR-17-0568 Abstract Transcriptional programs in embryogenesis and cancer, such as the epithelial-to-mesenchymal transition (EMT), ensure cellular plasticity, an essential feature of carcinoma progression. As effectors of signal transduction, the bromodomain and extraterminal […]

Insight into chromatin therapies for breast cancer could aid personalized medicine

Wednesday, February 7, 2018 Provided by: Boston University School of Medicine | Source: Medical Xpress Most traditional chemotherapy for cancer has dangerous side effects, but new research is finding ways to develop ‘targeted agents’ that reduce the side effects and are better tailored to individual patient needs. While these innovations are exciting, a new study shows how certain cancer […]

Avrum Spira Leads “Stand Up to Cancer” Dream Team

Wednesday, November 1, 2017 Written by: Sara Rimer | Source: BUToday Armed with $12 million, researchers aim for early detection of lung cancer Can lung cancer, rarely diagnosed until it’s in an advanced and deadly stage, be nipped in the bud? Avrum Spira and his team intend to find out. Spira (ENG’02), Alexander Graham Bell Professor in Health […]

Shipley Center Website Offers Prostate Cancer Facts for Patients

Tuesday, September 19, 2017 Written by: Rich Barlow | Source: BUToday One in every seven men in the United States will get prostate cancer, making it the second most common type, after skin cancer, for American men. It tends to be a slow-growing disease but can sprint to life-threatening severity if detected too late. Screening for prostate cancer can […]

Avrum Spira Receives Entrepreneur Award from the American Thoracic Society

Avrum Spira, MD, MSc, professor of medicine, pathology and bioinformatics at BUSM, is the inaugural recipient of the Research Innovation and Translation Achievement Award from the American Thoracic Society (ATS). Spira, who also directs the BU-BMC Cancer Center, was recognized for the translational impact his work has had on early detection of lung cancer as […]

BU Paves Way for Avi Spira’s $10M-Plus Partnership with Industry

Major pharma company supports research into early diagnosis—and prevention—of COPD and lung cancer As a pulmonary physician scientist, Avi Spira is driven to get his breakthroughs in molecular biomarkers for the early diagnosis of lung cancer and chronic obstructive pulmonary disease (COPD) into clinical care. “I’m a doctor, I want to help people,” says Spira, […]

Finding Lung Cancer in the Nose

Tuesday, February 28, 2017 Written by: Barbara Moran | Source: BUToday Lung cancer is the deadliest form of cancer in the United States—and in the world. According to the National Cancer Institute, it accounts for more than a quarter of cancer deaths in this country, killing about 158,000 people in 2016. Because lung cancer is so lethal, many […]