Jie Zhang , PhD
Assistant Professor, Medicine
Biography
Jie Zhang, PhD, is an Assistant Professor of Medicine at Boston University Chobanian & Avedisian School of Medicine and a Principal Investigator of Nephrology at Boston Medical Center. Dr. Zhang received her BS degree from Jilin University in China and her PhD degree from the University of South Florida. She joined the faculty of BU/BMC and established her independent research laboratory in 2023. Dr. Zhang’s laboratory employs a combination of classical renal physiology techniques such as micropuncture and microperfusion, as well as cutting-edge molecular biology technologies such as single-cell RNA sequencing and genetically engineered animal models to explore fundamental questions within the field of nephrology. Her research endeavors have been supported by prestigious fellowships and grants, including the American Heart Association Pre-Doctoral Fellowship, the American Society of Nephrology Ben J. Lipps Post-Doctoral Fellowship, the American Society of Nephrology Carl W. Gottschalk Research Scholar Grant, and NIH-NIDDK R01 Grant.
Websites
Education
- University of South Florida, PhD
- University of Mississippi, PhD
- Jilin University, BS
Publications
- Published on 3/8/2023
Iglesias M, Wang H, Krause-Hauch M, Ren D, Zoungrana LI, Li Z, Zhang J, Wei J, Yadav N, Patel K, Fatmi MK, Liu R, Lesnefsky EJ, Li J. Sestrin2 Mediates Metformin Rescued the Age-Related Cardiac Dysfunctions of Cardiorenal Syndrome Type 3. Cells. 2023 Mar 08; 12(6). PMID: 36980186.
Read at: PubMed - Published on 1/30/2023
Liu R, Juncos LA, Lu Y, Wei J, Zhang J, Wang L, Lai EY, Carlstrom M, Persson AEG. The Role of Macula Densa Nitric Oxide Synthase 1 Beta Splice Variant in Modulating Tubuloglomerular Feedback. Compr Physiol. 2023 Jan 30; 13(1):4215-4229. PMID: 36715280.
Read at: PubMed - Published on 8/1/2022
Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R. Corrigendum to Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R. "Role of the macula densa sodium glucose cotransporter type 1-neuronal nitric oxide synthase-tubuloglomerular feedback pathway in diabetic hyperfiltration." Kidney Int. 2022;101:541-550. Kidney Int. 2022 Aug; 102(2):448. PMID: 35870819.
Read at: PubMed - Published on 3/9/2022
Chen W, Wang L, Liang P, Mast J, Mathis C, Liu CY, Wei J, Zhang J, Fu L, Juncos LA, Buggs J, Liu R. Reducing ischemic kidney injury through application of a synchronization modulation electric field to maintain Na+/K+-ATPase functions. Sci Transl Med. 2022 Mar 09; 14(635):eabj4906. PMID: 35263146.
Read at: PubMed - Published on 11/26/2021
Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R. Role of the macula densa sodium glucose cotransporter type 1-neuronal nitric oxide synthase-tubuloglomerular feedback pathway in diabetic hyperfiltration. Kidney Int. 2022 Mar; 101(3):541-550. PMID: 34843754.
Read at: PubMed - Published on 10/18/2021
Zhang J, Wang X, Cui Y, Jiang S, Wei J, Chan J, Thalakola A, Le T, Xu L, Zhao L, Wang L, Jiang K, Cheng F, Patel T, Buggs J, Vallon V, Liu R. Knockout of Macula Densa Neuronal Nitric Oxide Synthase Increases Blood Pressure in db/db Mice. Hypertension. 2021 Dec; 78(6):1760-1770. PMID: 34657443.
Read at: PubMed - Published on 6/14/2021
Wei J, Zhang J, Jiang S, Xu L, Qu L, Pang B, Jiang K, Wang L, Intapad S, Buggs J, Cheng F, Mohapatra S, Juncos LA, Osborn JL, Granger JP, Liu R. Macula Densa NOS1ß Modulates Renal Hemodynamics and Blood Pressure during Pregnancy: Role in Gestational Hypertension. J Am Soc Nephrol. 2021 Oct; 32(10):2485-2500. PMID: 34127535.
Read at: PubMed - Published on 10/12/2020
Zhang J, Qu L, Wei J, Jiang S, Xu L, Wang L, Cheng F, Jiang K, Buggs J, Liu R. A new mechanism for the sex differences in angiotensin II-induced hypertension: the role of macula densa NOS1ß-mediated tubuloglomerular feedback. Am J Physiol Renal Physiol. 2020 Nov 01; 319(5):F908-F919. PMID: 33044868.
Read at: PubMed - Published on 12/23/2019
Zhang J, Zhu J, Wei J, Jiang S, Xu L, Qu L, Yang K, Wang L, Buggs J, Cheng F, Tan X, Liu R. New Mechanism for the Sex Differences in Salt-Sensitive Hypertension: The Role of Macula Densa NOS1ß-Mediated Tubuloglomerular Feedback. Hypertension. 2020 Feb; 75(2):449-457. PMID: 31865794.
Read at: PubMed - Published on 12/16/2019
Wei J, Zhu J, Zhang J, Jiang S, Qu L, Wang L, Buggs J, Tan X, Cheng F, Liu R. Aging Impairs Renal Autoregulation in Mice. Hypertension. 2020 Feb; 75(2):405-412. PMID: 31838907.
Read at: PubMed
View 21 more publications: View full profile at BUMC