Ann Rasmusson, MD is the Psychiatry Liaison, PTSD Research and Education, at VA Boston Healthcare System, a Research Associate of the VA National Center for PTSD, Women’s Health Science Division, and an Associate Professor of Psychiatry at Boston University. She earned her undergraduate degree at North Dakota State University and MD at the University of Chicago before completing a residency in pediatrics at Johns Hopkins and a neuropsychopharmacology research fellowship and psychiatry residency at Yale University School of Medicine.
Dr. Rasmusson’s basic research focused on understanding the role of the amygdala, prefrontal cortex, and hippocampus in coordinating hypothalamic-pituitary-adrenal (HPA) axis, mesoprefrontal cortical monoamine, and behavioral responses to unconditioned and conditioned stress. Her clinical research has contributed to the current expanded view of neurobiological factors that contribute to PTSD risk and stress resilience. This research has evolved to focus on gender differences in the neurobiology of PTSD and a role for neuroactive steroids and neuropeptides in the pathophysiology and treatment of PTSD and its comorbidities. She is currently a Lead Investigator of a DOD sponsored multisite Phase II investigation of the GABAergic neuroactive steroid ganaxolone in the treatment of PTSD and Principal Investigator on an NIMH study of GABAergic neuroactive steroids in the pathophysiology of PTSD, a VA Merit Review investigating gender-related neurobiological factors that promote refractory nicotine dependence in veterans with PTSD, and the VA RR&D sponsored Translational Center for Traumatic Brain Injury and Stress (TRACTS) investigation of Cognitive Processing Therapy (CPT) efficacy in PTSD with and without TBI. She is the author of 56 peer-reviewed papers, reviews, and chapters and is the mother of one lovely teenage daughter.
- VA Boston Healthcare System
- Pritzker School of Medicine, MD
- University of North Dakota, BS
- University of North Dakota, BS
- Published on 9/1/2020
Scioli ER, Smith BN, Whitworth JW, Spiro A, Esterman M, Dutra S, Bogdan KM, Eld A, Rasmusson AM. Moderated mediation for exercise maintenance in pain and posttraumatic stress disorder: A randomized trial. Health Psychol. 2020 Sep; 39(9):826-840. PMID: 32833484.
- Published on 5/15/2020
Pineles SL, Nillni YI, Pinna G, Webb A, Arditte Hall KA, Fonda JR, Irvine J, King MW, Hauger RL, Resick PA, Orr SP, Rasmusson AM. Associations between PTSD-Related extinction retention deficits in women and plasma steroids that modulate brain GABAA and NMDA receptor activity. Neurobiol Stress. 2020 Nov; 13:100225. PMID: 32490055.
- Published on 4/18/2020
Kim BK, Fonda JR, Hauger RL, Pinna G, Anderson GM, Valovski IT, Rasmusson AM. Composite contributions of cerebrospinal fluid GABAergic neurosteroids, neuropeptide Y and interleukin-6 to PTSD symptom severity in men with PTSD. Neurobiol Stress. 2020 May; 12:100220. PMID: 32435669.
- Published on 11/14/2019
Kimball A, Dichtel LE, Nyer MB, Mischoulon D, Fisher LB, Cusin C, Dording CM, Trinh NH, Yeung A, Haines MS, Sung JC, Pinna G, Rasmusson AM, Carpenter LL, Fava M, Klibanski A, Miller KK. The allopregnanolone to progesterone ratio across the menstrual cycle and in menopause. Psychoneuroendocrinology. 2020 02; 112:104512. PMID: 31780185.
- Published on 1/7/2019
Fonda JR, Gregor KL, Fortier CB, Scioli-Salter ER, McGlinchey RE, Rasmusson A. Tobacco dependence is associated with increased risk for multi-morbid clustering of posttraumatic stress disorder, depressive disorder, and pain among post-9/11 deployed veterans. Psychopharmacology (Berl). 2019 Jun; 236(6):1729-1739. PMID: 30617565.
- Published on 1/3/2019
Robinson ME, McKee AC, Salat DH, Rasmusson AM, Radigan LJ, Catana C, Milberg WP, McGlinchey RE. Positron emission tomography of tau in Iraq and Afghanistan Veterans with blast neurotrauma. Neuroimage Clin. 2019; 21:101651. PMID: 30642757.
- Published on 12/19/2018
Liang JJ, Rasmusson AM. Overview of the Molecular Steps in Steroidogenesis of the GABAergic Neurosteroids Allopregnanolone and Pregnanolone. Chronic Stress (Thousand Oaks). 2018 Jan-Dec; 2:2470547018818555. PMID: 32440589.
- Published on 11/22/2018
Rasmusson AM, King MW, Valovski I, Gregor K, Scioli-Salter E, Pineles SL, Hamouda M, Nillni YI, Anderson GM, Pinna G. Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD. Psychoneuroendocrinology. 2019 04; 102:95-104. PMID: 30529908.
- Published on 10/29/2018
Japuntich SJ, Lee LO, Pineles SL, Gregor K, Joos CM, Patton SC, Krishnan-Sarin S, Rasmusson AM. Contingency management and cognitive behavioral therapy for trauma-exposed smokers with and without posttraumatic stress disorder. Addict Behav. 2019 03; 90:136-142. PMID: 30391774.
- Published on 7/17/2018
Rasmusson AM, Pineles SL. Neurotransmitter, Peptide, and Steroid Hormone Abnormalities in PTSD: Biological Endophenotypes Relevant to Treatment. Curr Psychiatry Rep. 2018 07 17; 20(7):52. PMID: 30019147.
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