The project manager will be responsible for all aspects of the management and conduct of multiple biomedical and/or social-behavioral research studies, including clinical trials, reporting to the study PIs. This role manages all activities associated with these studies that could include multiple research teams, sites, participants, interventions, and assessments. Oversees day-to-day operations including identifying and securing needed resources; creating, implementing, monitoring, and updating project plans (e.g., manual of operating procedures, case report forms); preparation, submission, and update of regulatory documents (e.g., IRB); facilitating meetings; tracking tasks/deliverables to ensure timelines, milestones and/or goals are attained; monitoring and reporting progress as appropriate. This role will also be responsible for participant recruitment, screening, communications, scheduling, and may involve participant assessments and biospecimen handling. Ensures that all study activities are completed by strictly following BU/BUMC IRB, Good Clinical Practices (GCP), and all current local, state, and federal laws, regulations, guidance, policy and procedures, as applicable. The role will require presence at BU College of Health and Rehabilitation Sciences: Sargent College and BU School of Medicine on specific days each week.
A postdoctoral position is available in the laboratory of Dr. Giovanni Ligresti to study basic and translational aspects of lung fibrosis with specific emphasis on molecular mechanisms regulating endothelial cell responses and vascular dysfunction during sustained lung fibrogenesis. The work is to be conducted within a multidisciplinary laboratory featuring state-of-the-art resources, cell/tissue/animal models, and access to excellent core facilities.
Postdoctoral research positions are available in Trojanowska laboratory in the Arthritis and Autoimmune Diseases Center to investigate pathogenesis of scleroderma, a complex autoimmune disease characterized by inflammation, vasculopathy and skin and organ fibrosis. The current investigations focus on the mechanisms of vascular disease using novel transgenic mouse models that recapitulate vascular and lymphatic defects observed in scleroderma patients. The second area of research include investigations on the mechanisms of pulmonary hypertension (PAH) focusing on the cross-talk between endothelial and smooth muscle cells.