Dr. Arwa Badahdah has successfully defended her DSc dissertation, “Effect of a
Salivary Peptide on the Structure of Bacterial Pili and Bacterial Adhesion to Host
Dr. Badahdah completed her research in a Physiology & Biophysics lab, and is a
member of the Oral Biology & Periodontology program at the BU Goldman School of
She has passed her written Dental Board Exam, and will graduate in May 2014 with a
combined DDS / DSc degree.
Congratulations to Dr. Mengxiao Lu on a successful defense of her PhD dissertation “Structural Stability and Fusion of Human Low-Density Lipoproteins” (advisor: Dr. Gursky)
The journal Immunology has published Dr. Seaton’s article titled; “The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide.”
The article is titled;”Myosin-1c regulates the dynamic stability of E-cadherin–based cell–cell contacts in polarized Madin–Darby canine kidney cells” and can be found in the September 15 issue of Molecular Biology of the Cell.
“Similar to passengers on an urban transit system, every protein made in the cell has a specific destination and function. Channels in cell membranes help direct these proteins to their appropriate target. Researchers at Boston University School of Medicine (BUSM) and their colleagues have now captured images of these channels as they open to allow proteins to pass through a membrane, while the proteins are being made. These findings are published as a Letter in Nature.”
More information here.
Congratulations to Drs. Jing Wang and Esther Bullitt on their new publication in collaboration with Drs. J. Ptacek and K. Kirkegaard,
Double-Membraned Liposomes Sculpted by Poliovirus 3AB Protein
now in press at the Journal of Biological Chemistry.
Congratulations to Mengxiao Lu, a PhD student in the Gursky lab, who is a corresponding author on an invited review “Aggregation and fusion of low-density lipoproteins in vivo and in vitro” accepted for publication in BMC.
The BUSM has just been awarded a Shared Instrument Grant from the NIH to upgrade our Core Facility for Structural NMR. The proposal ”A Console Upgrade and Cryogenic Probe for a 500 MHz NMR System for Biomedical Research” will provide state-of-the art electronics and a superconducting probe that will increase the sensitivity of the instrument approximately ten-fold. This will provide superior spectra with less instrument time and allow research on samples not possible with the current instrument.
The PI of the proposal is C. James McKnight and the Major Users are Assen Marintchev, James Hamilton, Christopher Akey and David Atkinson from the Department of Physiology and Biophysics. The Major Users outside of Physiology and Biophysics are Susan Fisher (Microbiology), David Harris (Biochemistry), Erdjan Salih (Oral Biology) and Stephen Blacklow (Dana Farber Cancer Institute, Harvard Medical School). The upgraded Facility will be managed by Jonathan Vural.
Here is a link to the Core Facility for Structural NMR:
Congratulations to Dr. Olga Gursky for receiving a new RO1 grant to study “Structural stability and functional remodeling of high-density lipoproteins”.
Surface For Catalysis by Poliovirus RNA-dependent RNA Polymerase
by Jing Wang, John M Lyle, and Esther Bullitt
Jing received her PhD in the Bullitt lab in May 2012. Congratulations!