Sleep Medicine

The Sleep Medicine division has been focused on a wide spectrum of clinically oriented efforts. Current efforts include an examination of CPAP compliance in OSA patients with COVID-19. We are also exploring the impact of a special program designed to provide CPAP units to an, otherwise, underserved population. Collaborative efforts have also been ongoing with the Human Neurophysiology laboratory in the Department of Anatomy and Neurobiology. Recent efforts have been focused on the social impact of circadian rhythms. Other collaborative efforts have been ongoing with the Brain and Aging section of the Framingham Heart Study.

Faculty

Sanford H. Auerbach, M.D.
Joshua August, MD, Pediatric Neurology (Sleep Division)
Emily Cournoyer, NP
Natalia Sedo, NP
Alexis Cushman, NP

Ongoing projects

Sleep Polysomnographic bio markers of anxiety and depression
The impact of CPAP compliance on survival from COVID-19 in patients with OSA
The impact of a special CPAP program on outcomes in underserved OSA patients

Recent Publications

Yuan J, Liu X, Liu C, Ang AFA, Massaro J, Devine SA, Auerbach SH, Blusztajn JK, Au R, Jacques PF. Is dietary choline intake related to dementia and Alzheimer’s disease risk: results from the Framingham Heart Study. Am J Clin Nutr. 2022 Aug 2:nqac193. doi: 10.1093/ajcn/nqac193. Epub ahead of print. PMID: 35918258.

Yuan J, Au R, Karjadi C, Ang TF, Devine S, Auerbach S, DeCarli C, Libon DJ, Mez J, Lin H. Associations Between the Digital Clock Drawing Test and Brain Volume: Large Community-Based Prospective Cohort (Framingham Heart Study). J Med Internet Res. 2022 Apr 15;24(4):e34513. doi: 10.2196/34513. PMID: 35436225; PMCID: PMC9055470.

Zhang X, Tong T, Chang A, Ang TFA, Tao Q, Auerbach S, Devine S, Qiu WQ, Mez J, Massaro J, Lunetta KL, Au R, Farrer LA. Midlife lipid and glucose levels are associated with Alzheimer’s disease. Alzheimers Dement. 2022 Mar 23. doi: 10.1002/alz.12641. Epub ahead of print. PMID: 35319157.

Petrie BK, Sturzoiu T, Shulman J, Abbas S, Masoud H, Romero JR, Filina T, Nguyen TN, Lau H, Clark J, Auerbach S, Pyatkevich YG, Aparicio HJ. Questionnaire and Portable Sleep Test Screening of Sleep Disordered Breathing in Acute Stroke and TIA. J Clin Med. 2021 Aug 13;10(16):3568. doi: 10.3390/jcm10163568. PMID: 34441863; PMCID: PMC8396899.

Brooks C, Shaafi Kabiri N, Bhangu J, Cai X, Pickering E, Erb MK, Auerbach S, Bonato P, Moore TL, Mortazavi F, Thomas K. The impact of chronotype on circadian rest-activity rhythm and sleep characteristics across the week. Chronobiol Int. 2021 Jun 16;1-16. doi: 10.1080/07420528.2021.1937197. Online ahead of print.

Brooks C, Shaafi Kabiri N, Mortazavi F, Auerbach S, Bonato P, Erb MK, Czech M, Karlin D, Rolph T, Bhangu J, Thomas K. Variations in rest-activity rhythm are associated with clinically measured disease severity in Parkinson’s disease.Chronobiol Int. 2020 Jan 21:1-13. doi: 10.1080/07420528.2020.1715998. [Epub ahead of print] PMID: 31959001

Lin SH, Branson C, Leung J, Park L, Doshi N, Auerbach SH. Oximetry as an Accurate Tool for Identifying Moderate to Severe Sleep Apnea in Patients With Acute Stroke. J Clin Sleep Med. 2018 Dec 15;14(12):2065-2073. doi: 10.5664/jcsm.7538. PMID:30518446

Adams JW, Alvarez VE, Mez J, Huber BR, Tripodis Y, Xia W, Meng G, Kubilus CA, Cormier K, Kiernan PT, Daneshvar DH, Chua AS, Svirsky S, Nicks R, Abdolmohammadi B, Evers L, Solomon TM, Cherry JD, Aytan N, Mahar I, Devine S, Auerbach S, Alosco ML, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, Au R, McKee AC, Stein TD. Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports. J Neuropathol Exp Neurol. 2018 Sep 1;77(9):757-768. doi: 10.1093/jnen/nly065. PMID:30053297

Morgenthaler TI, Auerbach S, Casey KR, Kristo D, Maganti R, Ramar K, Zak R, Kartje R. Position Paper for the Treatment of Nightmare Disorder in Adults: An American Academy of Sleep Medicine Position Paper. J Clin Sleep Med. 2018 Jun 15;14(6):1041-1055. doi: 10.5664/jcsm.7178. PMID:29852917

Pase MP, Himali JJ, Grima NA, Beiser AS, Satizabal CL, Aparicio HJ, Thomas RJ, Gottlieb DJ, Auerbach SH, Seshadri S. Author response: Sleep architecture and the risk of incident dementia in the community. Neurology. 2018 Mar 6;90(10):487. doi: 10.1212/WNL.0000000000005047. No abstract available. PMID:29507137

Pase M, Himali JJ, Grima NA, Beiser AS, Satizabal CL, Aparicio HJ, Thomas R, Gottlieb DJ, Auerbach SH, Seshadri S. Sleep architecture and the risk of incident dementia in the community. Neurology. 2017 Sep 19;89(12):1244-1250. doi: 10.1212/WNL.0000000000004373. Epub 2017 Aug 23. PMID: 2883540

McInnis RP1 , Dodds, EB1 , Johnsen J, Auerbach S, Pyatkevich Y. CPAP Treats Enuresis in Adults with Obstructive Sleep Apnea. J Clin Sleep Med. 2017 Oct 15;13(10):1209-1212. doi: 10.5664/jcsm.6776. PMID:2885972

Westwood AJ, Beiser A, Jain N, Himali JJ, DeCarli C, Auerbach SH, Pase MP, Seshadri S. Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia. Neurology. 2017 Mar 21;88(12):1172-1179. doi: 10.1212/WNL.0000000000003732. Epub 2017 Feb 22. PMID:28228567

Auerbach S, Yaffe K. The link between sleep-disordered breathing and cognition in the elderly: New opportunities? Neurology. 2017 Jan 31;88(5):424-425. doi: 10.1212/WNL.0000000000003577. Epub 2016 Dec 30. PMID:28039313

Spector A R, Loriaux D, Alexandru D, Auerbach SH. (November 09, 2016) The Influence of the Menstrual Phases on Polysomnography. Cureus 8(11): e871. doi:10.7759/cureus.871

Bajaj N1, Johnsen J, Ghosh K and Auerbach SH. Are We Over PAP-Tizing our Patients? The AASM 2012 Criteria for Hypopnea Scoring and Impact on OSA Prevalence J Sleep Disor: Treat Care 2016, 5:3 http://dx.doi.org/10.4172/2325-9639.1000180.