STRAP PTM

STRAP PTM, the Software Tool for Rapid Annotation of Protein Post-Translational Modifications, helps you recognize global, differential post-translational modifications in large proteomics data sets.

overview

Downloads

STRAP PTM will be released in beta form soon.

Requirements

STRAP PTM requires Windows XP or higher with at least version 4.0 of the Microsoft .NET Framework installed.

Input

STRAP PTM takes protXML files (usually from the TPP) as its input. These files are grouped by experimental condition so that you can analyze how modifications appear, disappear, or change across experimental conditions.

Output

STRAP PTM generates PTM maps that allow you to visualize the modifications as they differ between experimental groups. Additionally, it assigns a “PTM score” to peptides based on the degree to which they are differentially modified.

PTMmap

A PTM map for the CD40 ligand protein exposed to different amounts of an oxidant.

More Information

For more information on STRAP PTM, please email cpctools@gmail.com.

STRAP PTM is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of merchantability or fitness for a particular purpose.

How to Cite STRAP

STRAP-PTM has been presented at the following ASMS and HUPO meetings:

ASMS 2011
ASMS 20112
HUPO WORLD CONGRESS 2012

Primary teaching affiliate
of BU School of Medicine