Tony E. Godfrey, PhD, Associate Chair, Surgical Research and Associate Professor of Surgery, Boston University School of Medicine, earned a bachelor’s of science degree in biochemistry from Brunel University in England, followed by a doctorate in molecular biology and biochemistry, also from Brunel. He attended the University of California, San Francisco, for postdoctoral fellowships and managed UCSF’s Genome Analysis Core Facility.
Most recently, Dr. Godfrey was a Research Associate Professor in the Department of Surgery at the University of Rochester Medical Center in Rochester, NY. Prior to this he was an Associate Professor of Pathology at Mt. Sinai School of Medicine in New York, NY.
Dr. Godfrey’s research is focused on cancer genetics and molecular pathology. Research projects use state-of-the-art genetic and genomic approaches to address clinical needs in the areas of cancer diagnosis, prognosis and therapy. Currently the major focus of Dr. Godfrey’s research is on Barrett’s esophagus and esophageal adenocarcinoma; a tumor with rapidly increasing incidence in the United States and other western countries. The Godfrey lab works closely with translational research teams comprised of surgeons, pathologists and oncologists in order to develop new molecular approaches to cancer detection, staging and treatment.
- Professor, Computational Biomedicine, Medicine, Boston University School of Medicine
- Brunel University, PhD
- Brunel University, BSc
- Published on 4/12/2017
Muñoz-Largacha JA, Gower AC, Sridhar P, Deshpande A, O'Hara CJ, Yamada E, Godfrey TE, Fernando HC, Litle VR. miRNA profiling of primary lung and head and neck squamous cell carcinomas: Addressing a diagnostic dilemma. J Thorac Cardiovasc Surg. 2017 Aug; 154(2):714-727. PMID: 28495058.
- Published on 3/2/2017
Ståhlberg A, Krzyzanowski PM, Egyud M, Filges S, Stein L, Godfrey TE. Simple multiplexed PCR-based barcoding of DNA for ultrasensitive mutation detection by next-generation sequencing. Nat Protoc. 2017 Apr; 12(4):664-682. PMID: 28253235.
- Published on 2/7/2017
Pang C, LaLonde A, Godfrey TE, Que J, Sun J, Wu TT, Zhou Z. Bile salt receptor TGR5 is highly expressed in esophageal adenocarcinoma and precancerous lesions with significantly worse overall survival and gender differences. Clin Exp Gastroenterol. 2017; 10:29-37. PMID: 28223834.
- Published on 4/7/2016
Ståhlberg A, Krzyzanowski PM, Jackson JB, Egyud M, Stein L, Godfrey TE. Simple, multiplexed, PCR-based barcoding of DNA enables sensitive mutation detection in liquid biopsies using sequencing. Nucleic Acids Res. 2016 Jun 20; 44(11):e105. PMID: 27060140.
- Published on 1/2/2016
Jackson JB, Choi DS, Luketich JD, Pennathur A, Ståhlberg A, Godfrey TE. Multiplex Preamplification of Serum DNA to Facilitate Reliable Detection of Extremely Rare Cancer Mutations in Circulating DNA by Digital PCR. J Mol Diagn. 2016 Mar; 18(2):235-43. PMID: 26752305.
- Published on 12/29/2015
Ghatak S, Reveiller M, Toia L, Ivanov AI, Zhou Z, Redmond EM, Godfrey TE, Peters JH. Bile Salts at Low pH Cause Dilation of Intercellular Spaces in In Vitro Stratified Primary Esophageal Cells, Possibly by Modulating Wnt Signaling. J Gastrointest Surg. 2016 Mar; 20(3):500-9. PMID: 26715559.
- Published on 7/1/2015
Andersson D, Akrap N, Svec D, Godfrey TE, Kubista M, Landberg G, Ståhlberg A. Properties of targeted preamplification in DNA and cDNA quantification. Expert Rev Mol Diagn. 2015; 15(8):1085-100. PMID: 26132215.
- Published on 7/1/2014
Bandla S, Peters JH, Ruff D, Chen SM, Li CY, Song K, Thoms K, Litle VR, Watson T, Chapurin N, Lada M, Pennathur A, Luketich JD, Peterson D, Dulak A, Lin L, Bass A, Beer DG, Godfrey TE, Zhou Z. Comparison of cancer-associated genetic abnormalities in columnar-lined esophagus tissues with and without goblet cells. Ann Surg. 2014 Jul; 260(1):72-80. PMID: 24509200.
- Published on 5/15/2014
Zhou Z, Xia Y, Bandla S, Zakharov V, Wu S, Peters J, Godfrey TE, Sun J. Vitamin D receptor is highly expressed in precancerous lesions and esophageal adenocarcinoma with significant sex difference. Hum Pathol. 2014 Aug; 45(8):1744-51. PMID: 24951052.
- Published on 4/17/2014
Zhou Z, Bandla S, Ye J, Xia Y, Que J, Luketich JD, Pennathur A, Peters JH, Tan D, Godfrey TE. Cyclin E involved in early stage carcinogenesis of esophageal adenocarcinoma by SNP DNA microarray and immunohistochemical studies. BMC Gastroenterol. 2014; 14:78. PMID: 24742107.
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