Noyan Gokce, MD

Professor, Medicine

Noyan Gokce
(617) 414-1565
75 E. Newton St Collamore Building

Biography

My area of expertise is studying disease mechanisms in vascular biology. My recent research has focused on the effect of obesity and inflammation on vascular dysfunction. I have received two R01 grants to support this line of investigation and have additionally received a 5-year PPG project grant with Dr. Ken Walsh. I also have extensive expertise in echocardigraphy and currently collaborate with several investigators in the Department of Medicine.

Other Positions

  • Active Staff Privileges, Medicine, Boston Medical Center

Education

  • Tufts University School of Medicine, MD
  • Brandeis University, BA

Publications

  • Published on 9/29/2017

    Farb MG, Park SY, Karki S, Gokce N. Assessment of Human Adipose Tissue Microvascular Function Using Videomicroscopy. J Vis Exp. 2017 Sep 29; (127). PMID: 28994775.

    Read at: PubMed
  • Published on 5/5/2017

    Zuriaga MA, Fuster JJ, Gokce N, Walsh K. Humans and Mice Display Opposing Patterns of "Browning" Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots. Front Cardiovasc Med. 2017; 4:27. PMID: 28529941.

    Read at: PubMed
  • Published on 4/14/2017

    Karki S, Ngo DTM, Farb MG, Park SY, Saggese SM, Hamburg NM, Carmine B, Hess DT, Walsh K, Gokce N. WNT5A regulates adipose tissue angiogenesis via antiangiogenic VEGF-A165b in obese humans. Am J Physiol Heart Circ Physiol. 2017 Jul 01; 313(1):H200-H206. PMID: 28411232.

    Read at: PubMed
  • Published on 9/28/2016

    Farb MG, Karki S, Park SY, Saggese SM, Carmine B, Hess DT, Apovian C, Fetterman JL, Bretón-Romero R, Hamburg NM, Fuster JJ, Zuriaga MA, Walsh K, Gokce N. WNT5A-JNK regulation of vascular insulin resistance in human obesity. Vasc Med. 2016 Dec; 21(6):489-496. PMID: 27688298.

    Read at: PubMed
  • Published on 5/27/2016

    Fuster JJ, Ouchi N, Gokce N, Walsh K. Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease. Circ Res. 2016 May 27; 118(11):1786-807. PMID: 27230642.

    Read at: PubMed
  • Published on 3/31/2016

    Fetterman JL, Holbrook M, Westbrook DG, Brown JA, Feeley KP, Bretón-Romero R, Linder EA, Berk BD, Weisbrod RM, Widlansky ME, Gokce N, Ballinger SW, Hamburg NM. Mitochondrial DNA damage and vascular function in patients with diabetes mellitus and atherosclerotic cardiovascular disease. Cardiovasc Diabetol. 2016 Mar 31; 15:53. PMID: 27036979.

    Read at: PubMed
  • Published on 2/13/2016

    Fetterman JL, Holbrook M, Flint N, Feng B, Bret?n-Romero R, Linder EA, Berk BD, Duess MA, Farb MG, Gokce N, Shirihai OS, Hamburg NM, Vita JA. Restoration of autophagy in endothelial cells from patients with diabetes mellitus improves nitric oxide signaling. Atherosclerosis. 2016 Apr; 247:207-17. PMID: 26926601.

    Read at: PubMed
  • Published on 1/21/2016

    Bretón-Romero R, Feng B, Holbrook M, Farb MG, Fetterman JL, Linder EA, Berk BD, Masaki N, Weisbrod RM, Inagaki E, Gokce N, Fuster JJ, Walsh K, Hamburg NM. Endothelial Dysfunction in Human Diabetes Is Mediated by Wnt5a-JNK Signaling. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):561-9. PMID: 26800561.

    Read at: PubMed
  • Published on 1/11/2016

    Tampakakis E, Tabit CE, Holbrook M, Linder EA, Berk BD, Frame AA, Bretón-Romero R, Fetterman JL, Gokce N, Vita JA, Hamburg NM. Intravenous Lipid Infusion Induces Endoplasmic Reticulum Stress in Endothelial Cells and Blood Mononuclear Cells of Healthy Adults. J Am Heart Assoc. 2016 Jan 11; 5(1). PMID: 26755554.

    Read at: PubMed
  • Published on 11/18/2015

    Karki S, Farb MG, Myers S, Apovian C, Hess DT, Gokce N. Effect of Bariatric Weight Loss on the Adipose Lipolytic Transcriptome in Obese Humans. Mediators Inflamm. 2015; 2015:106237. PMID: 26663986.

    Read at: PubMed

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