Jennifer Elizabeth Snyder-Cappione , PhD

Assistant Professor, Microbiology

Jennifer Snyder-Cappione
617.638.4296
72 E. Concord St Instructional (L)

Biography

Dr. Snyder-Cappione received her B.S. from Brandeis University and her Ph.D. from the University of Rochester Medical Center. Her doctoral research focus was the regulation of IFN-gamma and cytotoxic effector functions by CD8+ T cells. During her post-doctoral work at UCSF, she investigated the role of iNKT cells in HIV and Mycobacterium tuberculosis infections as well as sarcoidosis. Her current research interests include: (1) determining the diagnostic and prognostic potential of ex vivo immune functional profiling in human inflammatory diseases, (2) investigating the differentiation potential and lineage relationships of iNKT cell subsets, and (3) elucidating the role of T cell and iNKT cell exhaustion in the progression of infectious diseases and cancer.

Other Positions

  • Director, Flow Cytometry Core Facility, Boston University School of Medicine

Education

  • University of Rochester School of Medicine & Dentistry, PhD
  • University of Rochester School of Medicine & Dentistry, MS
  • Brandeis University, BS

Publications

  • Published on 3/7/2018

    Fleury M, Belkina AC, Proctor EA, Zammitti C, Simms RW, Lauffenburger DA, Snyder-Cappione JE, Lafyatis R, Dooms H. Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis. Arthritis Rheumatol. 2018 Apr; 70(4):566-577. PMID: 29245183.

    Read at: PubMed
  • Published on 12/30/2016

    Lentucci C, Belkina AC, Cederquist CT, Chan M, Johnson HE, Prasad S, Lopacinski A, Nikolajczyk BS, Monti S, Snyder-Cappione J, Tanasa B, Cardamone MD, Perissi V. Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development. J Biol Chem. 2017 Feb 17; 292(7):2754-2772. PMID: 28039360.

    Read at: PubMed
  • Published on 12/19/2016

    Merlini E, Tincati C, Biasin M, Saulle I, Cazzaniga FA, d'Arminio Monforte A, Cappione AJ, Snyder-Cappione J, Clerici M, Marchetti GC. Stimulation of PBMC and Monocyte-Derived Macrophages via Toll-Like Receptor Activates Innate Immune Pathways in HIV-Infected Patients on Virally Suppressive Combination Antiretroviral Therapy. Front Immunol. 2016; 7:614. PMID: 28066424.

    Read at: PubMed
  • Published on 10/5/2016

    Belkina AC, Snyder-Cappione JE. OMIP-037: 16-color panel to measure inhibitory receptor signatures from multiple human immune cell subsets. Cytometry A. 2017 02; 91(2):175-179. PMID: 27706900.

    Read at: PubMed
  • Published on 6/25/2013

    Snyder-Cappione JE, Nixon DF, Chi JC, Nguyen ML, Kirby CK, Milush JM, Koth LL. Invariant natural killer T (iNKT) cell exhaustion in sarcoidosis. Eur J Immunol. 2013 Aug; 43(8):2194-205. PMID: 23661497.

    Read at: PubMed
  • Published on 3/11/2013

    DeFuria J, Belkina AC, Jagannathan-Bogdan M, Snyder-Cappione J, Carr JD, Nersesova YR, Markham D, Strissel KJ, Watkins AA, Zhu M, Allen J, Bouchard J, Toraldo G, Jasuja R, Obin MS, McDonnell ME, Apovian C, Denis GV, Nikolajczyk BS. B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile. Proc Natl Acad Sci U S A. 2013 Mar 26; 110(13):5133-8. PMID: 23479618.

    Read at: PubMed
  • Published on 10/16/2012

    Snyder-Cappione JE, Nikolajczyk BS. When diet and exercise are not enough, think immunomodulation. Mol Aspects Med. 2013 Feb; 34(1):30-8. PMID: 23078865.

    Read at: PubMed
  • Published on 5/7/2012

    Tincati C, Cappione Iii AJ, Snyder-Cappione JE. Distinguishing Latent from Active Mycobacterium tuberculosis Infection Using Elispot Assays: Looking Beyond Interferon-gamma. Cells. 2012; 1(2):89-99. PMID: 24710416.

    Read at: PubMed
  • Published on 5/1/2012

    Carvalho KI, Bruno FR, Snyder-Cappione JE, Maeda SM, Tomimori J, Xavier MB, Haslett PA, Nixon DF, Kallas EG. Lower numbers of natural killer T cells in HIV-1 and Mycobacterium leprae co-infected patients. Immunology. 2012 May; 136(1):96-102. PMID: 22269018.

    Read at: PubMed
  • Published on 5/1/2012

    Tincati C, Cappione A.J., Snyder-Cappione J.E. Distinguishing Latent from Active Mycobacterium Tuberculosis Infection Using Elispot Assays: Looking Beyond Interferon-gamma. Cells. 2012; (1):89-99.

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