Bang-bon Bon Koo, PhD
Assistant Professor, Anatomy & Neurobiology
Biography
Dr.Koo’s research interests span the areas of neuroimaging, particularly the development of multi-modal magnetic resonance imaging (MRI) and analysis methods. Neuroimaging commonly aims to identify difference between healthy and unhealthy brains in a quantitative way. However, due to the complexity of the human brain, it is extremely difficult to analyze early stage or slow disease progressions from visually inspecting the image. Dr.Koo’s work focuses on developing novel imaging protocols and mapping methods with better sensitivities on monitoring neurological and functional changes in the brain. Dr.Koo also serves as an imaging core director at National Emerging Infectious Disease Laboratories (NEIDL). The goal is to develop multimodal imaging protocol that allows in-vivo monitoring on different stages of tissue inflammatory/immune responses.
Other Positions
- Faculty, National Emerging Infectious Disease Lab, Boston University
- Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- Hanyang University, PhD
- Hanyang University, MS
- Hanyang University, BS
Publications
- Published on 2/13/2024
Gordon S, Lee JS, Scott TM, Bhupathiraju S, Ordovas J, Kelly RS, Bhadelia R, Koo BB, Bigornia S, Tucker KL, Palacios N. Metabolites and MRI-Derived Markers of AD/ADRD Risk in a Puerto Rican Cohort. Res Sq. 2024 Feb 13. PMID: 38410484.
Read at: PubMed - Published on 12/12/2023
Guan Y, Cheng CH, Bellomo LI, Narain S, Bigornia SJ, Garelnabi MO, Scott T, Ordovás JM, Tucker KL, Bhadelia R, Koo BB. Corrigendum: APOE4 allele-specific associations between diet, multimodal biomarkers, and cognition among Puerto Rican adults in Massachusetts. Front Aging Neurosci. 2023; 15:1343591. PMID: 38149171.
Read at: PubMed - Published on 11/15/2023
Guan Y, Cheng CH, Bellomo LI, Narain S, Bigornia SJ, Garelnabi MO, Scott T, Ordovás JM, Tucker KL, Bhadelia R, Koo BB. APOE4 allele-specific associations between diet, multimodal biomarkers, and cognition among Puerto Rican adults in Massachusetts. Front Aging Neurosci. 2023; 15:1285333. PMID: 38035273.
Read at: PubMed - Published on 11/1/2023
He S, Guan Y, Cheng CH, Moore TL, Luebke JI, Killiany RJ, Rosene DL, Koo BB, Ou Y. Human-to-monkey transfer learning identifies the frontal white matter as a key determinant for predicting monkey brain age. Front Aging Neurosci. 2023; 15:1249415. PMID: 38020785.
Read at: PubMed - Published on 1/31/2023
Naeser MA, Martin PI, Ho MD, Krengel MH, Bogdanova Y, Knight JA, Hamblin MR, Fedoruk AE, Poole LG, Cheng C, Koo B. Transcranial Photobiomodulation Treatment: Significant Improvements in Four Ex-Football Players with Possible Chronic Traumatic Encephalopathy. J Alzheimers Dis Rep. 2023; 7(1):77-105. PMID: 36777329.
Read at: PubMed - Published on 1/17/2023
Koo BB, Guan Y. Author Response: Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort. Neurology. 2023 Jan 17; 100(3):164-165. PMID: 36646472.
Read at: PubMed - Published on 3/30/2022
Guan Y, Ebrahimzadeh SA, Cheng CH, Chen W, Leung T, Bigornia S, Palacios N, Garelnabi MO, Scott T, Bhadelia R, Tucker KL, Koo BB. Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort. Neurology. 2022 Apr 12; 98(15):e1534-e1544. PMID: 35354581.
Read at: PubMed - Published on 3/15/2022
Gonuguntla V, Yang E, Guan Y, Koo BB, Kim JH. Brain signatures based on structural MRI: Classification for MCI, PMCI, and AD. Hum Brain Mapp. 2022 Jun 15; 43(9):2845-2860. PMID: 35289025.
Read at: PubMed - Published on 1/3/2022
Yang E, Kim CK, Guan Y, Koo BB, Kim JH. 3D multi-scale residual fully convolutional neural network for segmentation of extremely large-sized kidney tumor. Comput Methods Programs Biomed. 2022 Mar; 215:106616. PMID: 35026623.
Read at: PubMed - Published on 10/6/2021
Cheng CH, Alshelh Z, Guan Y, Sullivan K, Loggia ML, Koo BB. Association of the tissue microstructural diffusivity and translocator protein PET in Gulf War Illness. Brain Behav Immun Health. 2021 Dec; 18:100364. PMID: 34693367.
Read at: PubMed
View 45 more publications: View full profile at BUMC