Three Program in Biomolecular Pharmacology PhD Graduate Students Receive NRSA Predoctoral Fellowships

September 22nd, 2017 in Student Spotlight

Three Program in Biomolecular Pharmacology Ph.D. graduate students have been award Ruth L. Kirschstein National Research Service Award Predoctoral Fellowships.

SelfYoonjoo Lee, an M.D., Ph.D. graduate student who is conducting her thesis research in the laboratory of Vickery Trinkhaus-Randall, Ph.D., Professor of Biochemistry and Ophthalmology, received her F30 Ruth L. Kirschstein NRSA Individual Predoctoral MD/PhD or Other Dual-Doctoral Fellowship from the National Eye Institute. Yoonjoo’s research is on “The Role of Sustained Oscillations in the Wound Healing Response.”

 

Alissa FrameAlissa Frame, an M.D./Ph.D. graduate student in the Program in Biomolecular Pharmacology, has been awarded a F31 Ruth L. Kirschtein NRSA Individual Predoctoral fFellowship from the National Heart, Lung, and Blood Institute. Her pre-doctoral research is on “Renal and Neural Mechanisms of Age-Related Hypertension.”

Alissa is carrying out her research in the Laboratory for Cardiovascular-Renal Research under the mentorship of Richard D. Wainford, Ph.D., Associate Profession of Pharmacology and Medicine, Section of Cardiovascular Medicine and member of the Whitaker Cardiovascular Institute.

Slide1 - Version 3Cassie Moore, a Ph.D. graduate student in the Program in Bimolecular Pharmacology, the Graduate Program for Neuroscience (GPN), and the Transformative Training Program in Addiction Sciences (TTPAS), has been awarded an F31 Ruth L. Kirschstein NRSA Individual Predoctoral Fellowship from National Institute on Drug Abuse (NIDA) of the National Institutes of Health. Her proposal, entitled “CRF modulation of reward function in compulsive eating,” will focus on the underlying neurobiological mechanisms of compulsive eating behavior and examine potential overlaps with drug addiction. Her training under this award includes using viral and transgenic tools (viral-mediated gene knockdown, Cre recombinase-driver animals) in a unique combination with clinically relevant animal models (palatable diet cycling, intra-cranial self stimulation, and intravenous drug self-administration).

Cassie is co-sponsored for the award by Pietro Cottone, Ph.D., Associate Professor of Pharmacology and Psychiatry and Co-Director of the Laboratory of Addictive Disorders and Dr. Klaus Miczek, Professor of Psychology at Tufts University.

Congratulations to Yoonjoo, Alissa, and Cassie!

Alissa Frame AwardNRSA Pre-doctoral Fellowship from NHLBI

September 5th, 2017 in Student Spotlight

Alissa Frame, an M.D./Ph.D. graduate student in the Program in Biomolecular Pharmacology, has been awarded a Ruth L. Kirschtein National Research Service Award pre-doctoral fellowship from the National Heart, Lung, and Blood Institute. Her pre-doctoral research is on “Renal and Neural Mechanisms of Age-Related Hypertension.”

Alissa is carrying out her research in the Laboratory for Cardiovascular-Renal Research under the mentorship of Richard D. Wainford, Ph.D., Associate Profession of Pharmacology and Medicine, Section of Cardiovascular Medicine and member of the Whitaker Cardiovascular Institute.

Congratulations, Alissa!

Dr. Pietro Cottone Speaks at The Royal Society’s “Of Mice and Mental Health: Facilitating Dialogue Between Basic and Clinical Neuroscientists”

June 21st, 2017 in Faculty Spotlight

Pietro Cottone, Ph.D., Associate Professor of Pharmacology and Psychiatry, made a presentation on the “Neurobiology of Compulsive Eating” at The Royal Society’s “Of Mice and Mental Health: Facilitating Dialogue Between Basic and Clinical Neuroscientists” in London on April 24-25, 2017. Based upon his current research, Dr. Cottone and his research group in the Laboratory of Addictive Disorders tested the hypothesis that “one of the underlying mechanisms of compulsive eating involves the negative reinforcing properties palatable food . . .”  According to their studies, rats who were deprived of regular access to highly palatable food demonstrated “spontaneous emotional signs of palatable food withdrawal, including anxiety- and depressive-like behavior,”  that was “accompanied by increased corticotropin-releasing factor expression (CRF),” and that “administration of a selective CRF1 receptor antagonist . . . was able to block both the overeating . . . and negative emotional state.” These results are important in ultimately discovering novel therapeutics to combat compulsive eating.  The manuscript with details of this research will be published in The Royal Society’s journal, “Philosophical Transactions of the Royal Society B.”

 

Ryan Quinton Receives Predoctoral Fellowship from the Canadian Institutes of Health

May 26th, 2017 in Student Spotlight

Congratulations to Ryan Quinton on receiving a predoctoral Fellowship from the Canadian Institutes of Health. This award is the equivalent of an F30 predoctoral fellowship in the United States and will provide $35,000 per year for three years to cover his expenses.

Ryan is an MD/PhD currently pursuing his PhD graduate research in the Laboratory of Cancer Biology under the mentorship of Neil J. Ganem, Ph.D. Ryan joined the BU NIGMS sponsored Biomolecular Pharmacology training program in fall 2015. His research focuses on identifying YAP/TAZ dependence and synthetic lethality across cohort of breast cancer cell lines.

Kudos, Ryan!

1 May 2017 BU Pharmacology & Experimental Therapeutics – Pfizer Symposium: Emerging Technologies In Therapeutics

April 7th, 2017 in Recent News

The BU Pharmacology & Experimental Therapeutics – Pfizer Symposium: Emerging Technologies in Therapeutics was held on Monday, 1 May 2017 in the Boston University Trustees Ballroom, 1 Silber Way, 9th Floor, on the Boston University Charles River Campus. This event, which is the result of a long-term training partnership between the Department of Pharmacology & Experimental Therapeutics and Pfizer.

Kendra Kobrin and Jonathan Freedman Receive the 2017 Joseph Cochin Award in Pharmacology and Medical Ethics Award

March 17th, 2017 in Student Spotlight

At the Student Award Ceremony on Match Day, March 17th, Kendra Kobrin and Jonathan Freedman were awarded the 2017 Joseph Cochin Award in Pharmacology and Medical Ethics. This award honors the memory of Joseph Cochin, MD, PhD, who served as Professor of Pharmacology and Experimental Therapeutics at BUSM for many years. Dr. Cochin was an internationally recognized expert on opioid analgesia, pain control and medical ethics.

Kendra Kobrin
Kendra, a student in the Biomolecular Pharmacology Training Program from 2011-2015, received this award in recognition of her high achievement in pharmacology and accomplishments in research under the mentorship of Gary B. Kaplan, M.D., Professor of Psychiatry and Pharmacology & Experimental Therapeutics.

 

Jonathan Freedman
Jonathan Freedman, also a student in the Biomolecular Pharmacology Training Program from 2011-2015, was rewarded for his high achievement in pharmacology and research accomplishments under the mentorship of Mark W. Grinstaff, Ph.D., Distinguished Professor of Translational Research, Biomedical Engineering, Chemistry, Materials Science and Engineering, and Medicine.

 

Kendra and Jonathan will receive their MD and PhD degrees at the BUSM May Graduation Ceremony.

Congratulations to Kendra and Jonathan!

Brandon Maziuk Selected by the BU BEST Program as BU Representative to the AAAS CASE Workshop in Washington, DC

February 28th, 2017 in Student Spotlight

Brandon Maziuk, a Program in Biomolecular Pharmacology PhD graduate student, has been selected as one of two students by the Boston University Broadening Experiences in Scientific Training (BEST) program to represent Boston University at the AAAS Catalyzing Advocacy for Science and Engineering (CASE) Workshop in Washington, DC, April 2-5, 2017. Brandon was chosen from a pool of BEST applicants.

Now in the 3rd year of his pre-doctoral training, Brandon is conducting his thesis research in the Laboratory of Neurodegeneration under the mentorship of Benjamin Wolozin, MD, PhD, Professor of Pharmacology and Neurology. His research projects focus on the role of RNA binding proteins in neurodegenerative disorders with emphasis on tauopathy and Alzheimer’s disease. Using a variety of molecular techniques with mouse models, cell culture systems and human tissues he investigates how RNA binding protein aggregation drives early neurodegeneration.

The CASE workshop provides an opportunity for undergraduate and graduate students in science, mathematics, and engineering, to learn about science policy and advocacy. At the workshop, Brandon will have the opportunity to learn about effective science communication and meet with elected Members of Congress as a science advocate. As a BEST program representative, Boston University will cover transportation, lodging and registration costs to attend the CASE workshop.

Congratulations to Brandon on being selected for this honor.

Dr. Benjamin Wolozin Receives AAAS and 2017 Jack Spivack Excellence in Neurosciences Honors

February 9th, 2017 in Faculty Spotlight

Benjamin Wolozin, M.D., Ph.D., Professor of Pharmacology and Neurology at Boston University School of Medicine, has been named a Fellow of the American Association for the Advancement of Science (AAAS). He was elected for his contributions to molecular and translational neuroscience, particularly discovery of the role of cholesterol in Alzheimer’s disease.

On January 26, 2017, Dr. Karen Antman, BUSM Dean and BUMC Provost announced that Dr. Wolozin is the recipient of the Jack Spivack Excellence in Neurosciences Award for 2017. His discovery of the essential role of RNA Binding proteins in the pathology of tauopathies, including Alzheimer’s disease, represents a paradigm shift in our understanding of these diseases. With this discovery comes dramatic new opportunities for therapeutic interventions for Alzheimer’s disease and other tauopathies, based on targeting important members of the translational stress response, such as TIA1.

Congratulations to Ben!

Dr. Annina Deleo Receives Alzheimers Association Research Grant

December 13th, 2016 in Recent News

Annina Leo, Ph.D., Postdoctoral Fellow in the Laboratory of Molecular NeuroTherapeutics under the mentorship of Tsuneya Ikezu, M.D., Ph.D., was selected as one of two Boston University School of Medicine recipients  of the 2016 Alzheimer’s Association Grant Award.  Dr. Deleo’s research application on “Characterization of Human AD Brain-Derived Exosomes on Tau Propagation” focus on the question, “How do cellular transport pathways contribute to the movement of abnormal tau protein throughout the brain in Alzheimer’s disease.” Dr. Deleo will receive $175, 000 over 3 years to support her postdoctoral research.

Congratulations, Annina!

 

 

Dr. David Farb Speaks at Science on Film Presentation of “Embrace of the Serpent”

November 8th, 2016 in Recent News

Dr. David Farb was the featured speaker at a sold-out Science on Screen presentation of “Embrace of the Serpent” at the Coolidge Corner Theatre in Brookline. This stunning film is based on the real-life journals of Theodor Koch-Grünberg and Richard Evans Schultes and their quest through the Columbian Amazon for the sacred and rare Yakruna plant. The film focuses on their encounter with Karamakate, a shaman and the last survivor of his people, with whom they forge a profound friendship over 40 years and learn ancient lessons in the sacred and medicinal powers of plants.
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As a neuropharmacologist, Dr. Farb’s presentation focused on the use of plants, particularly hallucinogens, by shaman throughout history and how these “entheogens” were subsequently studied and at times even exploited following their discovery by western scientists in the 20th century.

Please click here to see a video of Dr. Farb’s talk.

Science on Screen is supported by a grant from the Alfred P. Sloan Foundation with additional support from Gesmer Updegrove LLP, Rubin Anders Scientific, and Ken Loveday and Ellen Hoffman, Brookline, and co-presented by the Museum of Science.