Congratulations to Brandon Maziuk on receiving a Ruth L. Kirschstein National Research Service Award from the National Institute of Neurological Disorders and Stroke (NINDS). Brandon is a PhD graduate student in the NIGMS supported Biomolecular Pharmacology Training Program. His F31 application is titled “Dysfunction of mRNA Metabolism in Tauopathy,” and this award will support this research over the next three years. Brandon is carrying out his dissertation research in the Laboratory of Neurodegeneration under the mentorship and direction of Benjamin Wolozin, M.D./Ph.D., Professor of Pharmacology and Neurology and an expert on neurological disease.
Well done, Brandon!
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Yoonjoo Lee and two additional students, Alissa Frame and Cassie Moore, receive NRSAs – Individual Predoctoral Fellowships
Yoonjoo Lee Awarded the Ruth L. Kirschstein NRSA Individual Pre-doctoral Fellowship from NEI (F30)
Yoonjoo Lee, an M.D./Ph.D. graduate student in the Program in Biomolecular Pharmacology, has been awarded a Ruth L. Kirschtein National Research Service Award pre-doctoral fellowship from the National Eye Institute. Her pre-doctoral research is on “The Role of Sustained Oscillations of the Wound Healing Response”.
Alissa Frame Awarded the NRSA Pre-doctoral Fellowship from NIDDKD (F31)
Alissa Frame, an M.D./Ph.D. graduate student in the Program in Biomolecular Pharmacology, has been awarded a Ruth L. Kirschtein National Research Service Award pre-doctoral fellowship from the National Institute of Diabetes and Digestive and Kidney Diseases. Her pre-doctoral research is on “Renal and Neural Mechanisms of Age-Related Hypertension.”
Alissa is carrying out her research in the Laboratory for Cardiovascular-Renal Research under the mentorship of Richard D. Wainford, Ph.D., Associate Professor of Pharmacology and Medicine, Section of Cardiovascular Medicine and member of the Whitaker Cardiovascular Institute.
Cassie Moore Awarded the Ruth L. Kirschstein NRSA Individual Pre-doctoral Fellowship from NIDA (F31)
Cassie Moore, a Ph.D. graduate student in the Program in Biomolecular Pharmacology/ Program in Neuroscience, has been awarded a Ruth L. Kirschtein National Research Service Award pre-doctoral fellowship from the National Institute on Drug Abuse. Her pre-doctoral research is on “CRF Modulation of Reward Function in Compulsive Eating.”
Cassie is carrying out her research in the Laboratory of Addictive Disorders under the mentorship of Pietro Cottone, Ph.D., Associate Professor of Pharmacology and Medicine, Section of Addictive Disorders.
Dr. Pietro Cottone Speaks at The Royal Society’s “Of Mice and Mental Health: Facilitating Dialogue Between Basic and Clinical Neuroscientists”
Pietro Cottone, Ph.D., Associate Professor of Pharmacology and Psychiatry, made a presentation on the “Neurobiology of Compulsive Eating” at The Royal Society’s “Of Mice and Mental Health: Facilitating Dialogue Between Basic and Clinical Neuroscientists” in London on April 24-25, 2017. Based upon his current research, Dr. Cottone and his research group in the Laboratory of Addictive Disorders tested the hypothesis that “one of the underlying mechanisms of compulsive eating involves the negative reinforcing properties palatable food . . .” According to their studies, rats who were deprived of regular access to highly palatable food demonstrated “spontaneous emotional signs of palatable food withdrawal, including anxiety- and depressive-like behavior,” that was “accompanied by increased corticotropin-releasing factor expression (CRF),” and that “administration of a selective CRF1 receptor antagonist . . . was able to block both the overeating . . . and negative emotional state.” These results are important in ultimately discovering novel therapeutics to combat compulsive eating. The manuscript with details of this research will be published in The Royal Society’s journal, “Philosophical Transactions of the Royal Society B.”
Congratulations to Ryan Quinton on receiving a predoctoral Fellowship from the Canadian Institutes of Health. This award is the equivalent of an F30 predoctoral fellowship in the United States and will provide $35,000 per year for three years to cover his expenses.
Ryan is an MD/PhD currently pursuing his PhD graduate research in the Laboratory of Cancer Biology under the mentorship of Neil J. Ganem, Ph.D. Ryan joined the BU NIGMS sponsored Biomolecular Pharmacology training program in fall 2015. His research focuses on identifying YAP/TAZ dependence and synthetic lethality across cohort of breast cancer cell lines.
1 May 2017 BU Pharmacology & Experimental Therapeutics – Pfizer Symposium: Emerging Technologies In Therapeutics
The BU Pharmacology & Experimental Therapeutics – Pfizer Symposium: Emerging Technologies in Therapeutics was held on Monday, 1 May 2017 in the Boston University Trustees Ballroom, 1 Silber Way, 9th Floor, on the Boston University Charles River Campus. This event, which is the result of a long-term training partnership between the Department of Pharmacology & Experimental Therapeutics and Pfizer.
Kendra Kobrin and Jonathan Freedman Receive the 2017 Joseph Cochin Award in Pharmacology and Medical Ethics Award
At the Student Award Ceremony on Match Day, March 17th, Kendra Kobrin and Jonathan Freedman were awarded the 2017 Joseph Cochin Award in Pharmacology and Medical Ethics. This award honors the memory of Joseph Cochin, MD, PhD, who served as Professor of Pharmacology and Experimental Therapeutics at BUSM for many years. Dr. Cochin was an internationally recognized expert on opioid analgesia, pain control and medical ethics.
Kendra, a student in the Biomolecular Pharmacology Training Program from 2011-2015, received this award in recognition of her high achievement in pharmacology and accomplishments in research under the mentorship of Gary B. Kaplan, M.D., Professor of Psychiatry and Pharmacology & Experimental Therapeutics.
Jonathan Freedman, also a student in the Biomolecular Pharmacology Training Program from 2011-2015, was rewarded for his high achievement in pharmacology and research accomplishments under the mentorship of Mark W. Grinstaff, Ph.D., Distinguished Professor of Translational Research, Biomedical Engineering, Chemistry, Materials Science and Engineering, and Medicine.
Kendra and Jonathan will receive their MD and PhD degrees at the BUSM May Graduation Ceremony.
Congratulations to Kendra and Jonathan!
Brandon Maziuk Selected by the BU BEST Program as BU Representative to the AAAS CASE Workshop in Washington, DC
Brandon Maziuk, a Program in Biomolecular Pharmacology PhD graduate student, has been selected as one of two students by the Boston University Broadening Experiences in Scientific Training (BEST) program to represent Boston University at the AAAS Catalyzing Advocacy for Science and Engineering (CASE) Workshop in Washington, DC, April 2-5, 2017. Brandon was chosen from a pool of BEST applicants.
Now in the 3rd year of his pre-doctoral training, Brandon is conducting his thesis research in the Laboratory of Neurodegeneration under the mentorship of Benjamin Wolozin, MD, PhD, Professor of Pharmacology and Neurology. His research projects focus on the role of RNA binding proteins in neurodegenerative disorders with emphasis on tauopathy and Alzheimer’s disease. Using a variety of molecular techniques with mouse models, cell culture systems and human tissues he investigates how RNA binding protein aggregation drives early neurodegeneration.
The CASE workshop provides an opportunity for undergraduate and graduate students in science, mathematics, and engineering, to learn about science policy and advocacy. At the workshop, Brandon will have the opportunity to learn about effective science communication and meet with elected Members of Congress as a science advocate. As a BEST program representative, Boston University will cover transportation, lodging and registration costs to attend the CASE workshop.
Congratulations to Brandon on being selected for this honor.
Benjamin Wolozin, M.D., Ph.D., Professor of Pharmacology and Neurology at Boston University School of Medicine, has been named a Fellow of the American Association for the Advancement of Science (AAAS). He was elected for his contributions to molecular and translational neuroscience, particularly discovery of the role of cholesterol in Alzheimer’s disease.
On January 26, 2017, Dr. Karen Antman, BUSM Dean and BUMC Provost announced that Dr. Wolozin is the recipient of the Jack Spivack Excellence in Neurosciences Award for 2017. His discovery of the essential role of RNA Binding proteins in the pathology of tauopathies, including Alzheimer’s disease, represents a paradigm shift in our understanding of these diseases. With this discovery comes dramatic new opportunities for therapeutic interventions for Alzheimer’s disease and other tauopathies, based on targeting important members of the translational stress response, such as TIA1.
Congratulations to Ben!
Annina Leo, Ph.D., Postdoctoral Fellow in the Laboratory of Molecular NeuroTherapeutics under the mentorship of Tsuneya Ikezu, M.D., Ph.D., was selected as one of two Boston University School of Medicine recipients of the 2016 Alzheimer’s Association Grant Award. Dr. Deleo’s research application on “Characterization of Human AD Brain-Derived Exosomes on Tau Propagation” focus on the question, “How do cellular transport pathways contribute to the movement of abnormal tau protein throughout the brain in Alzheimer’s disease.” Dr. Deleo will receive $175, 000 over 3 years to support her postdoctoral research.