Mass Spectrometry Course GMS BI 793

Mass Spectrometry, Proteomics, and Functional Genomics–Spring, 2024

Catherine E. Costello (CEC)
Cheng Lin (CL)
Manveen Sethi  (MS)
Chaoshuang Xia (CX)
Joe Zaia (JZ)

Guest lecturer:
Bing Wang (BHW)


The course meets Tuesdays from 3-4:50pm in BUSM, 670 Albany St. Rm. 107/108 –  Campus Map

The lecture handout will be posted the day before each lecture. Please download and print the handout before the lecture.  Make sure you are downloading the 2024 version of the material.

Zoom link for remote learners

For access to Zoom recordings of lectures, please contact

For registered students, there will be a weekly problem set and a final paper.

Final Paper Instructions

Please fill out the participant profile and bring it with you to the first lecture.
BI-793 Student profile 2024

The lecture content is password protected. Please contact one of the instructors for access.

The links to the lectures are given below (contents will be updated the day before the lecture):

Lecture 1: Introduction; Lab tour, January 23 2024 (CEC)
Lecture 2: Mass Spectrometry Fundamentals, January 30, 2024 (CL)
Lecture 3: Ionization Methods and Tandem Mass Spectrometry, February 6, 2024 (CL)
Lecture 4: Mass Analyzers, February 13, 2024 (CL)
No class, Monday classes held on February 20, 2024
Lecture 5: MS of Peptides and Proteins, February 27, 2024 (JZ)
No class, spring break, March 5, 2024 (Lecture 6 will be taught over Zoom on March 5)
Lecture 6: Proteomics and Databases, March 12, 2024 (MS) (Note the date change above)
Lecture 6a: Lab Demos: MSn, Database Searching, March 13-18, 2024 (CX)
Lecture 7: Noncovalent Complexes, April 2, 2024 (MS)
Lecture 8: MS of Nucleic Acids: March 26, 2024 (BHW)
Lecture 9: Affinity Methods, March 19, 2024 (JZ)
Lecture 10: MS Imaging and Profiling, April 9, 2024 (JZ)
Lecture 11: MS of Carbohydrates, April 16, 2024 (JZ)
Lecture 12: MS of Lipids, Glycoconjugates, April 23, 2024 (CEC)
Lecture 13: Medical Applications, April 30, 2024 (CEC)

Final Papers Due May 9, 2024.