Tagged: antibodies from plants

Block That Sperm! (The Atlantic Magazine, March, 2015)

May 29th, 2015 in Articles

Antibodies from plants: By inserting human genes into plants, scientists have been able to create disease-fighting proteins called “plantibodies,” which work just like the antibodies that the human immune system makes to ward off infections. Harvesting such proteins from plants—many plantibody researchers work with tobacco—is far cheaper than growing them in human cell cultures.(The world got a preview of plantibodies at work with ZMapp, the plantibody-based experimental drug that has been used to treat a handful of Ebola patients.) Researchers headed up by a team at Boston University are working to create a combination of plantibodies that would combat sperm, herpes, and HIV. The plantibodies would trap sperm and germs in vaginal mucus, paralyzing them until they are cleared from the body. Only the herpes and HIV plantibodies have been tested so far, and only in animals; sperm plantibodies are at an earlier stage of development. But eventually, the researchers hope to load all three proteins into a vaginal ring that would provide monthlong protection.

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