Explore our active clinical trials below, highlighting the innovative research opportunities aimed at advancing cardiovascular care and improving patient outcomes.

Heart Failure
  • Alleviant ALLAY-HF Study
    PI: Deepa Gopal
  • Alleviant ALLAY-HFrEF Study
    PI: Nir Ayalon
  • Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258) (FASTR-II)
    PI: Deepa Gopal
  • PROACTIVE-HF IDE Trial Heart Failure NYHA Class III (PROACTIVE-HF)
    PI: Nir Ayalon

Hypertrophic Cardiomyopathy
  • A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy (SONATA-HCM)
    PI: Wilson Colucci

Amyloid
  • Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)
    PI: Omar Siddiqi
  • Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
    PI: Frederick Ruberg
  • eMyosound
    PI: Deepa Gopal
    NCT: —
  • Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
    PI: Frederick Ruberg

Interventional Cardiology
  • Pulmonary Embolism – Thrombus Removal With Catheter-Directed Therapy (PE-TRACT)
    PI: Ashvin Pande
  • ELEVATE High-Risk PCI Pivotal Study (ELEVATE III)
    PI: Nir Ayalon

Myocarditis
  • Abatacept in Immune Checkpoint Inhibitor Myocarditis (ATRIUM)
    PI: Omar Siddiqi

Electrophysiology
  • The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation (REACT-AF)
    PI: Robert Helm
  • Body Surface Mapping
    PI: Robert Helm
    NCT: —
  • Anodal Biphasic Pacing
    PI: Robert Helm
    NCT: —

Cardiac Nuclear Medicine
  • Safer3
    PI: Shivda Pandey
    NCT: —