Research Program

Allergy & Immunology Fellowship Training

Fellows spend roughly 25% of year 1 and 70% of year 2 working on a research project. The research portion of the fellowship provides fellows with the opportunity to pursue many different avenues of research, including basic science, translational, and epidemiological research. On the basic science level, our faculty is engaged in pioneering research in the areas of pulmonary immunology, stem cell biology, and genetic and clinical epidemiological investigation of asthma. There are many areas of clinical expertise coupled with research programs, which offer fellows research projects of a translational nature. These include, but are not limited to asthma, sarcoidosis, interstitial lung disease and amyloidosis. Finally, the epidemiology group is a member of the NIH/NIAD Inner City Asthma Consortium and is also uniquely positioned to access to the Framingham database to answer fundamental questions related to airway disease (asthma and COPD).

an immunology figure

Fellows can elect to participate in the Pulmonary/Allergy Introduction to Research, a course conducted by the members of the Pulmonary Center research and ancillary medical school staff. This intense 2-week course is designed to facilitate and support the entry of fellows into research. The course consists of didactic sessions interspersed with lab practicums. Topics covered during this course include DNA isolation and analysis, gene cloning, RNA isolation and analysis, microarray technology, quantitative and RT-PCR, in-situ hybridization, cell culture techniques, immunohistochemistry, protein isolation, proteomics, transgenic and knockout mice, signal transduction, ethics, lab safety, how to design a clinical study, basics of epidemiology, and beginning statistics.

Some fellows opt to supplement their research experience by taking graduate level courses in molecular biology, bioinformatics, public health, and statistics. These courses are offered at Boston University, without charge.