• Title Assistant Professor
  • Education PhD: University of Barcelona, Spain
    Postdoctoral training: Yale University
  • Office K420
  • Phone 617-358-4520
  • Area of Interest Embryonic programming, developmental biology

The beginning of a new life is one of the most enigmatic and dynamic events in Biology. Upon fertilization, two highly specialized cells, sperm and oocyte, fuse together to develop into a new organism. However, it requires a vast reorganization of gene expression to render all the different tissues and cell types of the developing embryo from these primordial cells.

cifuenteslabmodelThe long term goal of my laboratory is to understand how post-transcriptional regulation of RNA and proteins orchestrates development of a single cell oocyte into a whole embryo and how these mechanisms can be extrapolated to other biological transitions such as cellular reprogramming or malignant transformation.

In the laboratory we use zebrafish as a model system to dissect the process of reprogramming in vivo within the context of a whole organism. The combination of fish embryo microinjection together with powerful genetic, genomic, and proteomic approaches provides a unique platform to address this central question in biology.

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