Owen Sanborn | Biochemistry & Cell Biology

Title Graduate Student – Cifuentes Lab
Education BS in biology, Saint Michael’s College
Office Cifuentes Lab – K420
Email osanborn@bu.edu
Area of Interest RNA-Protein Interactions, microRNA

Originally from Gilmanton, New Hampshire, I pursued my undergraduate education at Saint Michael’s College. After graduating, I joined the Barouch lab at Beth Israel Deaconess Medical Center as a research assistant, contributing to vaccine development for COVID-19 and HIV. Seeking new challenges, I transitioned to Laronde Therapeutics, a growing biotech company, where I focused on vaccine development using a circular RNA platform. My research at Laronde sparked a keen interest in RNA engineering and stability mechanisms, motivating me to pursue a PhD mentored by Dr. Daniel Cifuentes. In my doctoral studies, I investigate RNA-protein interactions, microRNA dynamics during embryogenesis, and develops tools to advance understanding in these areas.

Representative Publications

Collier, A.Y., McMahan, K., Yu, J., Tostanoski, L.H., Aguayo, R., Ansel, J., Chandrashekar, A., Patel, S., Apraku Bondzie, E., Sellers, D., Barrett, J., Sanborn, O., Wan, H., Chang, A., Anioke, T., Nkolola, J., Bradshaw, C., Jacob-Dolan, C., Feldman, J., Gebre, M., Borducchi, E.N., Liu, J., Schmidt, A.G., Suscovich, T., Linde, C., Alter, G., Hacker, M.R., Barouch, D.H. Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women. JAMA. (2021)

Yu, J., Tostanoski, L.H., Mercado, N.B., McMahan, K., Liu, J., Jacob-Dolan, C., Chandrashekar, A., Atyeo, C., Martinez, D.R., Anioke, T., Bondzie, E.A., Chang, A., Gardner, S., Giffin, V.M., Hope, D.L., Nampanya, F., Nkolola, J., Patel, S., Sanborn, O., Sellers, D., Wan, H., Hayes, T., Bauer, K., Pessaint, L., Valentin, D., Flinchbaugh, Z., Brown, R., Cook, A., Bueno-Wilkerson, D., Teow, E., Andersen, H., Lewis, M.G., Martinot, A.J., Baric, R.S., Alter, G., Wegmann, F., Zahn, R., Schuitemaker, H., Barouch, D.H. Protective efficacy of Ad26.COV2.S against SARS-CoV-2 B.1.351 in macaques. Nature. (2021)

Chandrashekar, A., Liu, J., Yu, J., McMahan, K., Tostanoski, L.H., Jacob-Dolan, C., Mercado, N.B., Anioke, T., Chang, A., Gardner, S., Giffin, V.M., Hope, D.L., Nampanya, F., Patel, S., Sanborn, O., Sellers, D., Wan, H., Pessaint, L, Valentin, D., Espina, B., Wattay, L., Ferrari, M.G., Brown, R., Cook, A., Bueno-Wilkerson, D., Teow, E., Andersen, H., Lewis, M.G., Barouch, D.H. Prior Infection with SARS-CoV-2 WA1/2020 Partially Protects Rhesus Macaques Against Re-Infection with B.1.1.7 and B.1.351 Variants. Science Translational Medicine (2021)

Gebre, M., Rauch, S., Roth, N., Yu, J., Chandrashekar, A., Mercado, N.B., He, X., Liu, J., McMahan, K., Martinot, A., Giffin, T., Hope, D., Patel, S., Sellers, D., Sanborn, O., Barrett, J., Liu, X., Cole, A.C., Pessaint, L., Valentin, D., Flinchbaugh, Z., Yalley-Ogunro, J., Muench, J., Brown, R., Cook, A., Teow, E., Andersen, H., Lewis, M.G., Mueller, S.O., Petsch, B., Barouch, D.H. Optimization of Non-Coding Regions Improves Protective Efficacy of an mRNA SARS-CoV-2 Vaccine in Nonhuman Primates. Nature. (2021)

Tostanoski, L.H., Chandrashekar, A., Patel, S., Yu, J., Jacob-Dolan, C., Chang, A., Powers, O.C., Sellers, D., Gardner, S., Barrett, J., Sanborn, O., Stephenson, K.E., Ansel, J.L., Jaegle, K., Seaman, M.S., Porto, M., Lok, M.,Spence, B., Cayer, K., Nase, D., Holman, S., Bradette, H., Kar, S. Andersen, H., Lewis, M.G., Cox, F.,Tolboom, J. T. B. M., Marit de Groot, A., Heerwegh, D., Gars, M.L., Sadoff, J., Wegmann, F., Zahn, R.C., Schuitemaker, H., Barouch D.H. Passive Transfer of Ad26.COV2.S-Elicited IgG from Humans Attenuates SARS-CoV-2 Disease in Hamster. NPJ Vaccines. (2021)

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Representative Publications

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