Christopher Williams, M.S.
Laboratory Supervisor
- Title Laboratory Supervisor
- Office E631
- Email scslab@bu.edu
- Phone 617-358-7255
- Education M.S., Clinical Research
B.A., Molecular Biology
Biography
Chris is the Laboratory Supervisor in the Single Cell Sequencing Core.
Education
M.S. in Clinical Research, Boston University
B.S. in Molecular Biology, North Carolina State
Publications
A.J. Hume, J. Olejnik, M. R. White, J. Huang, J. Turcinovic, B. Heiden, P.S. Bawa, C. J. Williams, N. G. Gorham, Y. O. Alekseyev, J. H. Connor, D. N. Kotton, E. Mühlberger. Heat Inactivation of Nipah Virus for Downstream Single-Cell RNA Sequencing Does Not Interfere with Sample Quality. Pathogens 9:62 (2024). https://doi.org/10.3390/pathogens13010062.
R. L. Petroff, C. Williams, J.-L. Li, J. W. MacDonald, T. K. Bammler, T. Richards, Prolonged, Low-Level Exposure to the Marine Toxin, Domoic Acid, and Measures of Neurotoxicity in Nonhuman Primates. Environmental Health Perspectives 130: EHP10923 (2022). https://doi.org/10.1289/EHP10923.
Research Interests
Single Cell Sequencing
Single Cell rnaSeq is at the forefront of genomics research. It offers researchers a great deal of information from immune profiling, to the epigenetic landscape and so much more. In particular the epigenetic landscape that can be observed from Single Cell rnaSeq is fascinating as it gives context to gene expression patterns observed in various organisms. The diversity and versatility of Single Cell rnaSeq makes it a cutting edge tool that is expanding our understanding of genomics.
Prevention and Treatment of Sickle Cell Disease
Sickle Cell Disease affects 1 in 365 Black or African American births. Research demonstrates that increased frequency of vaso-occlusive crises and acute chest syndrome. Many Sickle Cell Disease related deaths are a result of continual VOCs and ACS that are treated after they occur. Using incentive spirometry and/or BiPAP as a preventative tool could reduce the frequency of the occurrence of VOCs and ACS thus potential increase the length and quality of life for Sickle Cell Disease Patients.