Welcome New Students

The Department of Biochemistry would like to welcome 3 PhD graduate students who are joining us from the PIBS program. Joey Orofino has joined the Perissi lab, Nathan Kingston has joined the Varelas lab, and Debbie Chang has joined the Zaia lab.

Congratulations Biochemistry Russek Winners

The Henry I Russek Award Nominating Committee and the Executive Committee certainly had a tough time choosing this year's winners as the competition was keen.  We want to start by thanking the nominating committee for their efforts; Dr. Costello, Dr. Farmer, Dr. Kandror, Dr. Pilch and Dr. Schreiber.  Importantly, we want to thank all of applicants for their contributions and we look forward to seeing their work displayed on Russek Day.  
 
Now for the Department of Biochemistry's winners of the Henry I. Russek Student Achievement Day 2016; the third prize was awarded to Carly Cederquist, who is a student in Dr. Perissi's lab; the second prize was awarded to Kshitij Khatri, who is a student in Dr. Zaia's lab; the first prize was awarded to Aleks Szymaniak, who is a student in Dr. Varelas's lab .  Our congratulations go out to all of the winners as well as their advisors!  
 
So, we'll see you all on Friday, May 6th in Hiebert Lounge for Henry I. Russek Student Achievement Day 2016.  For those of you who have never attended, this is a day devoted to our graduate students, with presentations from students throughout the Division of Graduate Medical Sciences.  For those of you who have attended before, you know what's in store, and for the newcomers, I assure you that you won't be disappointed as Dr. Russek and the Division of Graduate Medical Sciences always plan a great day.  Thanks to the generous contributions of Dr. Russek and her family, the event promises to be a memorable one with the keynote address to be delivered by Dr. James Bradner, President of the Novartis Institutes for Biomedical Research.

Spotlight on Research—G proteins and disease

November 30th, 2015in Departmental News, MGM lab, Research News

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Congratulations to the Garcia-Marcos lab for their recent publication investigating the molecular basis for disease-linked mutations in G proteins. Heterotrimeric G proteins are molecular switches that control signal transduction. Many mutations in G proteins have been shown to cause human diseases. But not all these mutations are made equal. They found that two identical mutations can cause different diseases even if present in highly similar G proteins. By dissecting the biochemical properties of the different mutants, they elucidated the basis of how an identical mutation can make one G protein hyperactive in cancer and the second G protein inactive in rare inherited disease.

Congratulations Biochemistry Russek Award Winners

Congratulations to the The Department of Biochemistry's winners of the Henry I. Russek Student Achievement Day 2015.

The first prize goes to Samantha (Sami) Hiemer, who is a student in Dr. Varelas's lab, the second prize was awarded to Madelane Teran, who is a student in Dr. Nugent's lab and an honorable mention goes to Chendi Li.  Our congratulations go out to the winners as well as their advisors!

See you all on  Friday, May 1st in Hiebert Lounge for Henry I. Russek Student Achievement Day 2015.

New Research Discoveries—Beige Adipocyte Differentiation

January 30th, 2015in Departmental News, Research News

New Research Discoveries…Beige Adipocyte Differentiation

GprotCongratulations to the Farmer, Layne, and Smith laboratories for their recent publication in Cell investigating the mechanisms of beige adipocyte differentiation. Meghan McDonald and Chendi Li from the Farmer lab are co-first authors. This study found that BMPs induce brown adipogenesis from mesenchymal stem cells by inhibiting ROCK activity. Furthermore this study found that loss of the SRF cofactor MRTFA promoted browning and resistance to diet induced obesity.

Congratulations to Larry Pessolano

Congratulations to Larry Pessolano in the Schreiber lab for his abstract presentation at the American Heart Association Scientific Sessions 2014 (Nov. 15-19, Chicago, IL). Larry was invited to present this abstract entitled "Serum Amyloid A and Toll-Like Receptor 2 Activation Promote Dedifferentiation of Vascular Smooth Muscle Cells" to honor his selection as one of the top scoring abstracts at the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology 2014 Scientific Sessions last May.