BUSM Researcher Receives Prestigious Young Investigator Award
Adam Rose MD, MSc, FACP, an assistant professor of medicine at BUSM and a core investigator at the Center for Health Quality, Outcomes, and Economic Research at the Bedford VA Medical Center, has been named a 2009 Pier M. Mannucci Young Investigator prizewinner. Rose received this award for his article titled “Warfarin dose management affects INR Control” (Volume 7 Issue 1) which appeared in the Journal of Thrombosis and Haemostasis.
The Mannucci Prizes are awarded in honor of Pier M. Mannucci, the Journal’s first Editor-in-Chief, for the best articles by investigators younger than 35 years of age. The prizes are a contributed by Bayer HealthCare and recipients are selected by a jury of editors. Rose was one of five selected for this honor.
Rose’s research centers on measuring and improving the quality of care in outpatient oral anticoagulation. In this article, Rose and his co-authors used a representative database of patients receiving oral anticoagulation in the United States to examine prevalent practice with regard to warfarin dosing. They modeled the visit-level predictors of a dose change. They found that patients whose management included more or fewer dose changes than predicted by the model (i.e. too many or too few changes) had worsening anticoagulation control. The authors concluded that it is possible to model the decision to change the warfarin dose, and that judicious management of warfarin doses in clinical practice can contribute to improved anticoagulation control. This study is notable for the clinical relevance of its findings and for the novel methods that enabled the authors to examine this important but understudied topic.
Rose attended Harvard University and graduated with a degree in Music, Magna Cum Laude (1992-1996). He then went on to medical school at the University of Pennsylvania (1997-2001). Rose performed his residency and chief residency in Internal Medicine at Montefiore Medical Center in Bronx, New York (2001-2005). He then completed a fellowship in General Internal Medicine and a residency in Preventive Medicine at Boston Medical Center (2005-2008).