Maya Woodbury, Ph.D. – 2016
Pregnenolone Sulfate as a Modulator of Synaptic Plasticity
Tsuneya Ikezu, M.D./ Ph.D.
Position: Post-doc Ikezu lab





Kristen Hokenson, Ph.D. – 2016
BDNF: A Window on Intracellular Signaling that Controls Inhibitory Processes in the Brain
Shelley Russek, Ph.D.
Position: Medical Associate (Medical Writer), Chameleon (Healthcare Consultancy Group) New York City




Elizabeth Shenk, Ph.D. – 2016
Mechanisms of Tetraploidy-Induced Tumorigenesis
Neil Ganem, Ph.D.




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Kelli Cox, Ph.D. – 2016
Replication Stress and the Alternative Lengthening of Telomeres Pathway
Rachel Flynn, Ph.D.




Casey Carmichael, Ph.D. – 2016
Endogenous Central Signaling Mechanisms in Salt-Sensitive Hypertension
Richard Wainford, Ph.D.



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Kathryn Walsh, Ph.D. – 2016
Norepinephrine-Evoked Renal Regulation of Sodium Homeostasis in Salt-Sensitive Hypertension
Richard Wainford, Ph.D.



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Kavitha Sugunan, Ph.D. – 2015
Pregnenolone Sulfate as a Modulator of Synaptic Plasticity
David Farb, Ph.D.
Position: CTA ClinTec International




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Larissa Estrada, Ph.D. – 2015
Histochemical Markers of Myelin Damage and Impaired Remyelination in the Aging Rhesus Monkey Brain: Relationship to Cognitive Performance
Advisor: Douglas Rosen, Ph.D. 

Position: Postdoc Boston University School of Medicine – Department of Pharmacology & Experimental Therapeutics



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Joon Y. Boon (Yvette), Ph.D. – 2015
Post-Transcriptional Regulation of Alpha-Synuclein by Leucine-Rich Repeat Kinase 2 and Micro-RNAs with Implications for Parkinson’s Disease
Benjamin Wolozin, M.D./Ph.D.  



Cogswell ImageMeaghan Cogswell, Ph.D. – 2015
Thesis: A Disturbance in Inhibitory Systems Associated with Autism and Epilepsy
Advisor: Shelley Russek, Ph.D.
Position: Postdoc Boston University School of Medicine – Department of Pharmacology & Experimental Therapeutics




Megan Varnum, Ph.D. – 2015
An Anti-Inflammatory Glycoprotein, CD200, Restores Neurogenesis and Enhances Amyloid Phagocytosis in a Mouse Model of Alzheimer’s Disease
Tsuneya Ikezu, M.D./Ph.D.
Position: Postdoctoral Research Associate at the Scripps Research Institute in Florida.



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Nicholas Harrison, MA – 2015
Zebrafish Models of Human Leukemia: Technological Advances and Mechanical Insights 
Hui Feng, M.D./Ph.D.
Position: Technological Licensing Associate, Massachusetts Institute of Technology, Cambridge, mA



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Lissa Riley, Ph.D. – 2015
Effects of Cocaine on Visual Processing in Zebrafish
Irina Zhdanova, M.D./Ph.D.
Position: Postdoctoral Fellow at Boston VA, via Harvard Medical School, (designing cognitive rehabilitation programs for people with traumatic brain injury or attention problems) Boston, MA

Kobrin 2011-8-5 Image
Kendra Kobrin, Ph.D. – 2015
Morpholog of Nucleus Accumbens Neurons in Morphine Conditioned Place Preference
Advisor: Gary Kaplan, M.D.
Position: Currently completing the M.D. portion of the BUSM M.D./Ph.D. Program



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Jonathan Freedman, Ph.D. – 2015
Thesis: Synthesis and Characterization of Cationic Contrast Agents & Imaging of Articular Cartilage Using X-Ray Computed Tomography and Magnetic Resonance
Advisor: Mark Grinstaff, Ph.D.
Position: Currently completing the M.D. portion of the BUSM M.D./Ph.D. Program



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Kim Coughlan, Ph.D. – 2015

Inhibition of AMPK via Phosphorylation at SER485/491: Multiple Mechanisms of Regulation
Neil Ruderman M.D./D.Phil.
Position: Postdoctoral Fellow at Shire Pharmaceuticals (studying rare diseases in their Discovery Biology and Translational Research Group) Lexington, MA



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Tara Vanderweyde, Ph.D. – 2015
Regulated Protein Aggregation: How it Takes TIA-1 to Tangle
Benjamin Wolozin, M.D./Ph.D.
Position: Scientist at Aquinnah Pharmaceuticals – Cambridge, MA




Audrey Progress Report PhotoAudrey DiMauro, Ph.D. – 2014
Thesis: Functional Interactions Between the Hippocampus, Medial Entorhinal Cortex for Spatial and Nonspatial Processing
Advisor: Howard Eichenbaum, Ph.D., Professor of Psychology and Pharmacology. Director, Center for Memory and Brain; Director, Cognitive Neurobiology Laboratory; Director, Center for Neuroscience
Position: Currently completing the M.D. portion of the BUSM M.D./Ph.D. Program



Progress Report PhotoMelissa (Thompson) Smith, D.V.M., Ph.D. – 2014
Thesis: Redox regulation of cysteine-674 of SERCA 2 is critical for growth factor- and ischemia-induced angiogenesis
Advisor: Richard Cohen, M.D.
Position: Anesthesiologist, University of Georgia School of Veterinarian Medicine



Miyashiro 2011-9-28 Image

Joy Miyashiro, M.A. – 2014
Thesis: Evaluation of Resolvin E1 as a Potential Therapeutic for Rheumatoid Arthritis
Advisor: Tsuneya Ikezu, M.D., Ph.D., Professor of Pharmacology and Neurology
Position: Scientist at Ironwood Pharmaceuticals, Cambridge, MA.



IMAG0356Conor Smith, Ph.D. – 2014
Thesis: Non-Canonical Cell Signaling Actions of Pregnenolone Sulfate, A Neurosteroid that Increases Intracellular Calcium, Activates CREB Phosphorylation and Stimulates Trafficking of NMDA Receptors to the Surface of Neurons
Advisor: David H. Farb, Ph.D., Professor and Chair of Pharmacology
Position:Postdoctoral Research Associate, Dept. Anatomy & Cell Biology, University of Illinois at Chicago


Stewart Image 2Tara Stewart, Ph.D.- 2014
Thesis: A Systems Pharmacology Approach to Modulating Spatial Memory
Advisor: David H. Farb, Ph.D., Professor and Chair of Pharmacology
Position: Analyst, Decision Resources, Inc., Waltham, MA




Nicole-1Nicole Piche-Nicholas, M.A. – 2013
Thesis: Changes in Complementarity Determining Regions Significantly ALter IgB binding to Neonatal Fc Receptor
Advisor: Lioudmila Tchistiakova, Ph.D., Directory, Engineered Immune Protein Group, Pfizer Global Biotherapeutics
Position: Senior Scientist at Pfizer



Kieras 2011-9-8 ImageElizabeth Kieras, M.A. – 2013
Thesis: Functional Significance of the Interaction Between Inducible Costimulator (ICOS) and its Ligand (ICOSL) at Immune Cell Interfaces
Advisor: Lori Fitz, Ph.D., Principal Research Scientist II, Pfizer BioTherapeutics R&D, Inflammation and Immunology Research Unit
Position: Clinical Scientist at Pfizer



Fallica ImageBrian Fallica, Ph.D. – 2013
Thesis: 3D Culture Platform for the Study of Cancer Biology and Drug Response
Advisor: Muhammad Zaman, Ph.D., Assistant Professor, Biomedical Engineering
Position: Associate Business Consultant at ZS Associates



TraceypictureTracey Tucker, Ph.D. – 2013
Thesis: The Human Klotho VS Variant: Focus on the Processing and Function of the V, S and VS Isoform
Advisor: Carmela Abraham, Ph.D., Professor of Biochemistry
Position: Postdoctoral Research Fellow at Brigham and Women’s Hospital




AmyAmy Andreucci, M.A. – 2013
Anti-Inflammatory Drugs: An Appropriate Option for Treating Obesity?
Alan Herbert, MB.ChB./Ph.D., Associate Professor of Pharmacology and Neurology



Duffen ImageJennifer Lynn Parker Duffen, Ph.D. – 2013
Thesis: Adiponectin Receptors in Revascularization and Metabolic Dysfunction
Advisor: Kenneth Walsh, Ph.D., Professor of Medicine and Director, Whitaker Cardiovascular Institute
Position: Postdoctoral Fellow at Pfizer



DSC_5183-Rob-Freilich2-150x150Robert Freilich, Ph.D. – 2013  M.D. – 2015
Thesis: Roles of miR-155 in Microglia and Neurogenesis in Response to Toll-like Receptor Mediated Inflammation
Advisor: Tsuneya Ikezu, M.D., Ph.D., Professor of Pharmacology and Neurology
Position: Residency and Fellowship, NYU Medical Center, Medicine/Research Pathway



Gillespie-Image-2011-5-19-e1311012283241-150x150Earl Gillespie, Ph.D. – 2013
Thesis: Colonic Epithelial Genes in the Transition From Chronic Inflammation to Carcinoma in Colitis-Associated Cancer: Focus on the Truncated Neurokinin-1 Receptor
Advisor: Susan E. Leeman, Ph.D., Professor of Pharmacology
Position: Senior Analyst at Health Advances, Weston, MA



Snapshot-2010-10-21-09-32-42-144x150Amy Robinson, Ph.D., 2013
Thesis: Quantification of Brain-derived Neurotrophic Factor Expression in the Aging Monkey Brain
Advisor: Douglas Rosene, Ph.D., Professor of Anatomy and Neurobiology
Position: Postdoctoral Fellow at Kavli Institute for Systems Neuroscience/Centre for Neural Computation, Norwegian University of Science and Technology (NTNU)



Shapero-Image-1-150x150Kayle Shapero, Ph.D., 2013
Thesis: Interactions between Valvular Cells: Implications for Heart Valve Tissue Engineering
Advisors: John E. Mayer, Jr., M.D., Professor of Surgery, and Joyce E. Bischoff, Ph.D., Professor of Surgery, Children’s Hospital
Position: Medical Student at Tufts School of Medicine



Yohe 2011-7-18 ImageStefan Yohe, Ph.D. – 2013
Thesis: Superhydrophobic Materials for Drug Delivery
Advisor: Mark W. Grinstaff, Ph.D., Professor of Biomedical Engineering and Chemistry
Position: Associate Scientist in Drug Delivery at Genentech; San Francisco, CA



Benham Image 2Rebecca Benham, Ph.D. – 2012
Thesis: BDNF and JAK/STAT:Partners in Seizure-Induced GABAA Receptor Down Regulation.
Advisor: Shelley J. Russek, Ph.D., Professor Pharmacology & Experimental Therapeutics
Position: Postdoctoral Fellow, Laboratory of Genetic Neuropharmacology under the direction of Uwe Rudolf, M.D., Mailman Research Center, McLean Hospital/Harvard Medical School.


Burke 2011-9-21 Image Rebecca Burke, Ph.D. – 2012
Thesis: Bone Morphogenetic Protein 9 and Insulin-like Growth Factor 2 Modulate the Cholinergic Phenotype of the Basal Forebrain Cholinergic System: Relevance to Aging and Alzheimer’s Disease
Advisor: Krsztof Blusztajn, Ph.D., Professor Pathology and Laboratory Medicine
Position: Resident in Neurological Surgery at the University in Virginia


Ferree 2011-4-26 Image Retouched Andrew W. Ferree, Ph.D. – 2012
Mitochondria and Autophagy in the Context of Parkinson’s disease.
Advisor: Benjamin Wolozin, M.D./Ph.D., Professor of Pharmacology and Neurology
Position: Currently completing the M.D. portion of the BUSM M.D./Ph.D. Program.



Kim 2010-11-5 Image Julia H. Kim, Ph.D. – 2012
Growth Factor Regulation of Early Growth Response Factor 3 Localization and Function in Neurons
Advisor: Shelley J. Russek, Ph.D., Professor of Pharmacology & Experimental Therapeutics
Position: Validation Consultant at Axis Consulting; San Diego, CA



liqun linkedin final LiQun Liu, Ph.D. – 2012
The Biology of TDP-43 Stress Granules: Novel Insights About Protein Aggregation in Neurodegenerative Disease
Advisor: Benjamin Wolozin, M.D./Ph.D., Professor of Pharmacology and Neurology
Position: Clinical Development Project Manager, Massachusetts General Hospital



08e7837Terence Ta, Ph.D. – 2012 Biomedical Engineering/Biomolecular Pharmacology
pH/Thermosensitive Liposomes Modified with Poly(N-isopropylacrlyamid-co-propyacrylic acid) Copolymers for Focused Ultrasound-Triggered Release of Doxorubicin
Advisor: Tyrone Porter, Ph.D., Assistant Professor of Biomedical Engineering and Mechanical Engineering
Position: Scientist at GSK Vaccines, Cambridge, MA


Krenzel-Rojas Image Eileen Krenzel Rojas, Ph.D. – 2012
Thesis: Identification of Site-Specific Fatty Acid and Bilirubin Binding Sites on Human Serum Albumin by 2D-NMR Spectroscopy.
Advisor: James Hamilton, Ph.D., Professor of Physiology and Biophysics
Position: Postdoctoral Associate at Boston University School of Medicine



NicoleNicole Northrop, Ph.D. – 2012
Thesis: The Role of Neuroinflammation in Stress & Methamphetamine-Induced Damage
Advisor: Bryan Yamamoto, Ph.D., Adjunct Professor of Pharmacology
Position: Associate Research Scientist at the University of Toledo (Ohio) School of Medicine



Chan 2011-4-7 ImageDiane Chan, M.D., Ph.D. – 2011
LRRK2 and HDAC6: Directing Traffic at the Crossroads Between Autophagy, Translation and Neurodegeneration
Advisor: Benjamin Wolozin, M.D./Ph.D., Professor of Pharmacology and Neurology
Position: Currently completing her residency at Yale University in Neurology



Cathy WeiCathy Wei, M.D., Ph.D. – 2011
Thesis: The Effect of Brain Region-Specific Adenosine A2A Receptor Knockout on Cognition and Psychomotor Behavior in Mice
Advisor: Jiang-Fan Chen, M.D., Ph.D., Professor of Neurology and Pharmacology
Position: Currently completing her residency at Beth Israel Deaconess Harvard in Radiology



Bedard ImagePatty Bedard, Ph.D. – 2010
Inhibition of Innate Immune Functions by P-Selectin and CXCR1 in Rodent Models of Cardiovascular Disease, Obesity and Insulin Resistance
Advisor: Ruth Gimeno, Ph.D., Adjunct Associate Professor of Pharmacology
Postion: Senior R&D Project Manager, Principal Scientist, Cell Biology at Vital Therapies, Inc., San Diego, CA



MariaMaria Guillily, Ph.D. – 2010
Thesis: Understanding the Function of Parkinson’s Disease Associated Gene Leucine-Rich Repeat Kinase 2 in Caenorhabditis elegans: A Systems Biology Guided Approach
Advisor: Benjamin Wolozin, M.D., Ph.D., Professor of Pharmacology and Neurology
Position: Biological Science Online Educator (Neuroscience/Biomedical Science), Greater Boston



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Jacobi Cunningham, Ph.D. – 2010
“The Behavioral and Neurochemical Effects of Chronic Unpredictable Stress in Rats Pre-exposed to (+)3,4-methylenedioxymethamphetamine (MDMA)”
Advisor: Bryan Yamamoto, Ph.D.
Position: Scientist III at Alkermes.




Bethann Johnson, Ph.D. – 2010
“The Effect of Chronic Stress on +3,4-Methylenedioxymethamphetamine (MDMA) Neurotoxicity”
Advisor: Bryan Yamamoto, Ph.D., Adjunct Professor of Pharmacology
Position: Research Fellow at Harvard Medical School



DesbiensSophie Desbiens, Ph.D. – 2009 (BME)
Thesis: “Therapeutic Agents for Cocaine Addiction: A Systems Pharmacology Approach”
Advisor: David H. Farb, Ph.D., Professor and Chair, Department of Pharmacology & Experimental Therapeutics
Position: Assistant Director, Adaptive Licensing at MIT Center for Biomedical Innovation



GrisetAaron Griset, Ph.D.(BME) – 2009
Thesis: “Delivery of Paclitaxel Via pH-Responsive Polymeric Nanoparticles for Prevention of Lung Cancer and Mesothelioma Recurrence”
Advisor: Mark W. Grinstaff, Ph.D.
Position: Formulation Scientist at Selecta Biosciences.



WhittakerMatthew Whittaker, Ph.D – 2009
Thesis: “Pregnenolone Sulfate Modulate Neurotransmitter Release from Iolated Neuron Terminal of the Rate Striatum”
Advisor: David H. Farb, Ph.D.
Position Pharmacology/Toxicology Reviewer, Division of Pulmonary, Allergy, and Rheumatology Products, Center for Drug Evaluation and Review, FDA.



WinklerAaron Winkler, Ph.D. – 2009
Thesis: “Smoke Exposure of Primary Human Alveolar Macrophage-like Cells Impairs Nuclear Histone Deacetylase Expression and Results in Increased Cytokine Production”
Advisor: Cara Williams, Ph.D.
Position: Senior Research Scientist, Department of Inflammation, Pfizer Discovery.



Ausaf BariAusaf Bari, M.D., Ph.D. – 2008
Thesis: “The Role of the Nucleus Accumbens, Dopamine, and Glutamate Receptors in Cocaine Reward”
Advisor: R. Chris Pierce, Ph.D.
Position: Clinical Fellow in Functional Neurosurgery, University of Toronto



Price Blair, Ph.D. – 2008
Thesis: “Stimulation of Toll-like Receptor 2 in Human Platelets Induces a Thrombo-Inflammatory Response”
Advisor: Jane Freedman, M.D.
Position: Assistant Professor of Biology, Lynchburg College, Lynchburg, VA.


Walther Heine, M.D./Ph.D. – 2011
Thesis: “The Spatiotemporal Receptive Field Properties of Rat Retinal Ganglion Cells”
Advisor: Christopher L. Passaglia, Ph.D.
Position: Neurology Resident, UC San Diego Health System


Sonia Podvin, Ph.D. – 2008
Thesis: “Characterization of the Anti-Aging Protein Klotho in Normal Brain Aging and Neurodegeneration”
Advisor: Carmela Abraham, Ph.D.
Position: Postdoctoral Fellow in Neuroendocrinology at the University of California San Diego under the mentorship of Dr. Andrew Baird.


Jamie Raudensky Doyle, Ph.D. – 2008
Thesis: “Neurochemical and Physiological Effects of Chronic Stress on Methamphetamine Toxicity”
Advisor: Bryan Yamamoto, Ph.D.
Position: Postdoctoral Fellow, Molecular Pharmacology Research Center, Tufts Medical Center


Dan Roberts, M.D., Ph.D. – 2008
Thesis: “Regulation of Type A GABA Rector Alpha-4 Subunit and the N-Methyl-D Aspartate Receptor Subunit 1 by Brain-Derived Neurotrophic Factor”
Advisor: Shelley J. Russek, Ph.D.
Position: Dan is an Otolaryngology (ENT) resident in the Harvard Combined Program in Otolaryngology. He hopes that his future research will investigate the basic mechanisms of hearing loss and improve cochlear implantation technology.



Tina Wu, Ph.D. – 2008
Thesis: “Endothelial Nitric Oxide Synthase (eNOS) Modification by Hypochlorous Acid and the Development of a Hypochlorous Acid Oxidation Assay”
Advisor: John F. Keaney, Jr, MD
Position: Regulatory Affairs Project Manager



David Eyerman, Ph.D. – 2007
Thesis: “The Role of the Vesicular Monoamine Transporter 2 and Nicotinic Acetylcholine Receptors in Methamphetamine Toxicity to the Rat Striatum”
Advisor: Bryan Yamamoto, Ph.D.
Position: Senior Scientist II, Life Sciences and Toxicology at Alkermes



YinghuiYinghui Hu, Ph.D. – 2007
Thesis: “Differential Regulation of GABRA1 Gene Expression in the CNS: A Role for  CREB/ICER Transcription Facotrs and their Relevance to Temporal Lobe Epilepsy”
Advisor: Shelley J. Russek, Ph.D.
Position: Associate Principle Scientist, Neuroscience Discovery, Merck Research Laboritories



Karla Mark, Ph.D. – 2007
Thesis: “Methamphetamine Neurotoxicity and the Polysynaptic Activation of Glutamatergic Neurons in the Basal Ganglia”
Advisor: Bryan Yamamoto, Ph.D.
Position: Postdoctoral Research Fellow at Buck Institute for Age Research



Karen PageKaren M. Page, Ph.D. – 2007
“The role of PKC-theta in IL 12-induced IFN-gamma production by natural killer cells”
Advisor: Marion Kasaian, Ph.D.
Position: Clinical Scientist in Precision Medicine, BioTX Clinical R&D, Pfizer



Heath Schmidt, Ph.D. – 2007
Thesis: “The Limbic Circuitry Underlying the Reinstatement of Cocaine-Seeking Behavior in Rats”
Advisor: R. Chris Pierce, Ph.D.
Position: Research Assistant Professor, Psychiatry, University of Pennsylvania School of Medicine.



Joseph Breier, Ph.D. – 2006
Thesis: “The Role of L-Tyrosine in the Neurotoxicity of (+) 3,4- Methylenedioxymethamphetamine (MDMA) in the Rate and in a Serotonin Cell Line”
Advisor: Bryan Yamamoto, Ph.D.
Position: Regulatory Toxicologist, Bayer CropScience LP



Kelley Burridge, Ph.D. – 2006 (BME)
Thesis: “Targeted Drug Delivery: Effects of Grafted Polyethylene Glycol on Ligand-Receptor Binding Under Flow”
Advisor: Joyce Wong, Ph.D.
Position: Postdoctoral Fellow, Department of Medicine, Boston Medical Center.



Snapshot 2010-10-20 16-16-37Lori Fitz, Ph.D. – 2005
Thesis: “Activation-Induced Changes in the Histamine Content of Murine Mast Cells and their Adhesion to NIH-3T3 Fibroblasts”
Advisor: Marion Kasaian, Ph.D.
Position: Principal Research Scientist II, Pfizer BioTherapeutics R&D, Inflammation and Immunology Research Unit.



JeffreySimardPhotoJeffrey Simard, Ph.D. – 2005
Thesis: “Fatty Acid Transport: Binding to Human Serum Albumin and Trafficking in Model and Biological Membranes”
Advisor: James Hamilton, Ph.D.
Position: Project/Sub-Group Leader at Chemical Genomics Centre