Bob (Xaralabos) Varelas

VarelasAssistant Professor

Boston University School of Medicine
Silvio Conte Building, K-620
72 E. Concord Street Boston, MA 02118
Phone: 617-638-4182
Lab Phone: 617-638-4184
Fax: 617-638-5339
Email: xvarelas

Education:

PhD, University of Alberta (Edmonton, Canada)

Postdoctoral Training:

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital (Toronto, Canada)

People:

Samantha Hiemer
Graduate Student
Aleksander Szymaniak
Graduate Student
Pooja Shah
Undergraduate student
Chelsea Fortin
Undergraduate student

Research Interests:

Our objectives are to gain insight into the mechanisms by which cell growth is coordinated with cell fate during animal development and disease. We are particularly interested in understanding the roles and regulation of the Hippo pathway, an essential signaling pathway that directs mechanical and microenvironmental cues to control cell proliferation, apoptosis, cell movements, and cell fate. We are incorporating both directed and systems-based approaches to define how the Hippo pathway controls stem and progenitor populations in development, and understand how deregulation of Hippo pathway signals impacts the progression of diseases, such as cancer.

Research Themes:

Signal Transduction and Cancer & Development

Lab links:

Selected Publications:

(Full list on Pubmed)