Bob (Xaralabos) Varelas


Assistant Professor
Varelas

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Contact Info

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Education:

PhD, University of Alberta (Edmonton, Canada)

Postdoctoral training:

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital (Toronto, Canada)

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Research Interests 

Themes: Cell Biology & Cancer & Cell Fate & Development

Our objectives are to gain insight into the mechanisms by which cell growth is coordinated with cell fate during animal development and disease. We are particularly interested in understanding the roles and regulation of the Hippo pathway, an essential signaling pathway that directs mechanical and microenvironmental cues to control cell proliferation, movements, and fate. We are incorporating genetic and biochemical approaches to: 1) define how the Hippo pathway controls stem and progenitor populations in development, and 2) understand the molecular mechanisms governing Hippo pathway activity with a focus on how deregulation of these mechanisms impacts the progression of diseases, such as cancer.

Current Projects

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(Full list on Pubmed)

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Lab members

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Lab News and Photos

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Funding

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Positions Available