Zaia Research Group

Yes! We are recruiting a PiBS graduate student during the 2021-22 academic year.

Our research focuses on  glycoprotein and proteoglycan biochemistry using mass spectrometry as the primary tool .

Matrisome glycoproteins and proteoglycans provide the microenvironment for brain cells.  Because these molecules are highly glycosylated and heterogeneous, there is little understanding of the structural changes that occur  in brain diseases.  We are building maps matrisome molecular structure related to normal brain physiology and diseases including schizophrenia, drug abuse, Parkinson’s disease.

Viral glycoproteins recognize host cell surfaces and mediate host-viral membrane fusion. Despite the availability of genetic sequencing and X-ray structural data, there is little understanding of the mature structures of viral glycoproteins. We are developing workflows for viral glycoproteomics and applying them to influenza A glycoproteins.

Zaia’s Dept. of Biochemistry research page

Complete publications list