Kara M. Smith, MD, MSCI
Associate Professor of Neurology

- Title Associate Professor of Neurology
- Office Shapiro Building, 725 Albany St., 7th floor, Boston, MA 02118
- Phone 617-638-8456
- Education Medical School: Tufts University School of Medicine (2009)
Internship: Beth Israel Deaconess Medical Center
Residency: Beth Israel Deaconess Medical Center (2013)
Fellowship: University of Pennsylvania (2015)
Board Certifications: Neurology
Special Interests: Parkinson’s disease, Movement Disorders, clinical trials
Publications:
DeSilva GS, Upadhyay P, Manxhari M, Gopal D, Smith KM. Variability in Vowel Space in Parkinson’s Disease: Associations With Cognitive and Motor Impairment. J Speech Lang Hear Res. 2024 Oct 8;67(10):3566-3578. doi: 10.1044/2024_JSLHR-24-00008. Epub 2024 Sep 11. PubMed PMID: 39259881; PubMed Central PMCID: PMC11482582.
Smith KM, Demers-Peel M, Manxhari C, Stepp CE. Voice Acoustic Instability During Spontaneous Speech in Parkinson’s Disease. J Voice. 2023 Jul 25;. doi: 10.1016/j.jvoice.2023.06.004. [Epub ahead of print] PubMed PMID: 37500359; PubMed Central PMCID: PMC10808279.
Andrade EIN, Manxhari C, Smith KM. Pausing before verb production is associated with mild cognitive impairment in Parkinson’s disease. Front Hum Neurosci. 2023;17:1102024. doi: 10.3389/fnhum.2023.1102024. eCollection 2023. PubMed PMID: 37113321; PubMed Central PMCID: PMC10126398.
Palacios N, Hannoun A, Flahive J, Ward D, Goostrey K, Deb A, Smith KM. Effect of Levodopa Initiation on the Gut Microbiota in Parkinson’s Disease. Front Neurol. 2021;12:574529. doi: 10.3389/fneur.2021.574529. eCollection 2021. PubMed PMID: 33746867; PubMed Central PMCID: PMC7970035.
Josephy-Hernandez S, Norise C, Han JY, Smith KM. Survey on Acceptance of Passive Technology Monitoring for Early Detection of Cognitive Impairment. Digit Biomark. 2021 Jan-Apr;5(1):9-15. doi: 10.1159/000512207. eCollection 2021 Jan-Apr. PubMed PMID: 33615117; PubMed Central PMCID: PMC7879311.
Ngo AB, Smith KM. Patient and Clinician Impressions of Cognitive Impairment in Parkinson’s Disease. J Parkinsons Dis. 2020;10(4):1695-1698. doi: 10.3233/JPD-202110. PubMed PMID: 32925096; PubMed Central PMCID: PMC7814400.
Smith KM, Caplan DN. Communication impairment in Parkinson’s disease: Impact of motor and cognitive symptoms on speech and language. Brain Lang. 2018 Oct;185:38-46. doi: 10.1016/j.bandl.2018.08.002. Epub 2018 Aug 6. Review. PubMed PMID: 30092448.
Smith KM, Ash S, Xie SX, Grossman M. Evaluation of Linguistic Markers of Word-Finding Difficulty and Cognition in Parkinson’s Disease. J Speech Lang Hear Res. 2018 Jul 13;61(7):1691-1699. doi: 10.1044/2018_JSLHR-L-17-0304. PubMed PMID: 29955824; PubMed Central PMCID: PMC6195062.
Kraemmer J, Smith K, Weintraub D, Guillemot V, Nalls MA, Cormier-Dequaire F, Moszer I, Brice A, Singleton AB, Corvol JC. Clinical-genetic model predicts incident impulse control disorders in Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2016 Oct;87(10):1106-11. doi: 10.1136/jnnp-2015-312848. Epub 2016 Apr 13. PubMed PMID: 27076492; PubMed Central PMCID: PMC5098340.
Smith KM, Xie SX, Weintraub D. Incident impulse control disorder symptoms and dopamine transporter imaging in Parkinson disease. J Neurol Neurosurg Psychiatry. 2016 Aug;87(8):864-70. doi: 10.1136/jnnp-2015-311827. Epub 2015 Nov 3. PubMed PMID: 26534930; PubMed Central PMCID: PMC4854795.
Smith KM, Spindler MA. Uncommon applications of deep brain stimulation in hyperkinetic movement disorders. Tremor Other Hyperkinet Mov (N Y). 2015;5:278. doi: 10.7916/D84X56HP. eCollection 2015. Review. PubMed PMID: 25713746; PubMed Central PMCID: PMC4314611.
Smith KM, Eyal E, Weintraub D. Combined rasagiline and antidepressant use in Parkinson disease in the ADAGIO study: effects on nonmotor symptoms and tolerability. JAMA Neurol. 2015 Jan;72(1):88-95. doi: 10.1001/jamaneurol.2014.2472. PubMed PMID: 25420207.
de la Riva P, Smith K, Xie SX, Weintraub D. Course of psychiatric symptoms and global cognition in early Parkinson disease. Neurology. 2014 Sep 16;83(12):1096-103. doi: 10.1212/WNL.0000000000000801. Epub 2014 Aug 15. PubMed PMID: 25128183; PubMed Central PMCID: PMC4166362.
Smith KM, Dahodwala N. Sex differences in Parkinson’s disease and other movement disorders. Exp Neurol. 2014 Sep;259:44-56. doi: 10.1016/j.expneurol.2014.03.010. Epub 2014 Mar 28. Review. PubMed PMID: 24681088.
Smith KM, Deik A, Stern MB, Thompson P. Undulating Lingual Dyskinesia With Symptomatic Palatal Tremor and Inferior Olivary Hypertrophy Following Cerebellar Hemisphere Hematoma. Mov Disord Clin Pract. 2014 Sep;1(3):245-246. doi: 10.1002/mdc3.12045. eCollection 2014 Sep. PubMed PMID: 30713858; PubMed Central PMCID: PMC6353367.
Smith KM, O’Connor M, Papavassiliou E, Tarsy D, Shih LC. Phonemic verbal fluency decline after subthalamic nucleus deep brain stimulation does not depend on number of microelectrode recordings or lead tip placement. Parkinsonism Relat Disord. 2014 Apr;20(4):400-4. doi: 10.1016/j.parkreldis.2014.01.008. Epub 2014 Jan 20. PubMed PMID: 24495709.
Feng W, Sidorov E, Smith K, Selim M. Recurrent lobar intracerebral hemorrhage in Tangier disease. J Stroke Cerebrovasc Dis. 2012 Nov;21(8):909.e5-6. doi: 10.1016/j.jstrokecerebrovasdis.2011.10.009. Epub 2011 Nov 30. PubMed PMID: 22133743.