AMPK, SREBP, and Lipid Metabolism

Dr. Yu Li’s oral presentations in ADA webcasts (2010) (2011)

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-induced Insulin Resistance

Slide 1


The Synthetic Polyphenol, S17834, Attenuates Accelerated Aortic Atherosclerosis in Insulin Resistant LDLR-/- mice

Slide 1


Confocal Microscopy Image of Increased Nuclear SREBP-1 (Green) in the Hepatocytes of Insulin Resistant Mice and Eliminated by S17834 Treatment

Slide 1

AMPK Directly Phosphorylates human SREBP-1c at Ser372 in vitro

Phospho-SREBP-1c (Ser372) antibody is available in Cell Signaling Technology (#9874) (http://www.cellsignal.com/products/9874.html)

Slide 1

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-induced Insulin Resistance

Slide 1