Layne Laboratory

Postdoctoral Research Position Available:

A postdoctoral research position is available to investigate the mechanisms of stromal activation in breast cancer funded by a Department of Defense Breakthrough Award. The project utilizes in vivo techniques with transgenic mice harboring fluorescent reporters with the long-term goal of identifying pathways activated in the cancer stroma that can be targeted with specific therapies. Immediate goals for the project include completing the analysis of activated cancer associated fibroblasts in tumors and analyzing specific cell populations by FACS and expression profiling. Experience with mice is essential and experienced scientists with MA degrees will be considered. Candidates must be eligible to start in early August. For more information please contact Matthew Layne, PhD, Department of Biochemistry, mlayne@bu.edu. Include a CV, description of your past research experiences, and names of 3 references.

Perissi Laboratory

One, or possibly two, postdoctoral positions are available in the Perissi Laboratory at Boston University School of Medicine to investigate the role of non-proteolytic ubiquitin signaling in the coordinated regulation of metabolic and pro-inflammatory signaling pathways.

The ideal candidate is a recent PhD graduate with significant experience in Molecular Biology, Cell Biology and Biochemistry who works well independently, but is also willing to integrate with other lab members and work with them as a team. Experience with protein biochemistry, complex purification and signal transduction is welcomed. Experience working with mouse models is a plus but is not required.

Interested candidates should send a CV, including contact information for 3 letters of reference, and a short statement describing experience, goals and reasons for the interest in this position to vperissi@bu.edu.

 

 

Faculty Positions—Genetics and Genomics

The Department of Biochemistry, in collaboration with the Genome Science Institute at Boston University School of Medicine is undertaking a major expansion in the areas of Genetics and Genomics. We invite applications at the Assistant, Associate, and Full Professor levels. Several positions are available, and these will be highly competitive with regard to start-up funds, newly renovated space, and salary.

We seek creative scientists using cutting-edge technologies and experimental systems to address important problems in Genetics and Genomics. Areas of interest include, but are not limited to, chromatin structure and function, epigenetics/epigenomics, single-cell genomics, metabolic regulation, control of gene expression, DNA damage and repair, stem cells and development, and cancer genomics. The position requires a Ph.D. or M.D., and relevant postdoctoral experience.

Applicants should submit a cover letter, curriculum vitae, statement of research interests, and list of publications to https://academicjobsonline.org/ajo/jobs/7645.

Letters of recommendation should be provided only if requested by the Search Committee. Applications will be reviewed beginning September 15, 2016, and continuing until the positions are filled. Please direct email queries to biochem@bu.edu.

Boston University is an equal opportunity and affirmative action employer.

Cifuentes Laboratory

Positions are available for extremely motivated Postdocs and Graduate Students willing to address fundamental questions of embryonic reprograming using zebrafish as a model system. Previous experience in molecular biology will be a plus, but even more important is their motivation to learn and adapt to scientific challenges and become positive members of the lab. To apply please send to Dr. Cifuentes a cover letter stating research interests, CV, and contact for three references.

Daniel Cifuentes
Boston University School of Medicine
72 E. Concord Street, K420
Boston, MA 02118
Email: Daniel Cifuentes

Harris Laboratory

NEURODEGENERATIVE DISEASES

Postdoctoral positions are available to study the cellular and molecular mechanisms underlying Alzheimer’s disease, prion diseases, and other neurodegenerative disorders due to protein aggregation. The laboratory is interested in understanding the cellular pathways that mediate the neurotoxicity of Aβ, prions, and other misfolded protein aggregates, and developing therapeutic approaches to block these pathways. A number of exciting projects are underway, spanning basic biology to drug discovery. The candidate will join a vibrant, multi-disciplinary group that is a leader in research on neurodegenerative disorders.

We are seeking scientists with a Ph.D. and/or M.D. degree, or the equivalent, and experience in one or more of the following areas: biochemistry, cell biology, chemical biology, protein structure, and mouse transgenic models.

Please send a curriculum vitae, statement of research interests, and the names of three references to:

David A. Harris, M.D., Ph.D.
Professor and Chair
Department of Biochemistry, Cell Biology & Genomics
Boston University School of Medicine
72 East Concord Street, K225
Boston, MA 02118 USA
E-mail: dhlab@bu.edu

Varelas laboratory

Graduate Student Positions

Interested students should apply to the PiBS program at Boston University (BU-PiBS). Once accepted to the program please email Dr. Varelas(xvarelas) to arrange a meeting to discuss projects and opportunities.

Postdoctoral Positions

Postdoctoral positions are available in the Varelas Lab to work on funded, multi-year, cell signaling projects. The overall goal of the Lab is to understand the roles and regulation of the Hippo pathway in a variety of areas, including stem cell biology, development, and diseases such as cancer. The successful candidate(s) will have opportunities to work with a vibrant group to learn and utilize a number of experimental approaches, including molecular biology and cell biology methods, and various animal models.

Candidates should hold a Ph.D. and/or M.D. degree, or the equivalent, and preferably have expertise in developmental mouse models. Qualified candidates must also be able to work independently, demonstrate excellent communication skills and work well within a group. To apply send a cover letter, curriculum vitae, and the names of three references to Dr. Varelas by email (xvarelas). Please note that only candidates selected for an interview will be contacted.

Garcia-Marcos Laboratory

We are looking for candidates with a recent Ph.D. and a strong background in Cell Biology, Molecular Biology and Biochemistry applied to Signal Transduction research, as demonstrated by a publication record. Prior knowledge of GPCR/G protein signal transduction is preferred but not essential.

Candidates are expected to have a strong commitment to academic research and to be able to work in a fast paced and demanding environment. We are looking for exceptionally motivated and creative individuals capable of advanced conceptual thinking. Candidates must be able to drive projects from beginning till the end independently as well as to participate in team-based efforts. Our laboratory is highly committed to the career development of trainees.

Experience in several of the topics/ techniques listed below is expected:

  • Cellular and Molecular Biology (Cell lines, primary cultures, BRET, microscopy, etc)
  • Protein biochemistry (purification, pulldowns, immunoprecipitation, etc)
  • Synthetic Biology (advanced cloning, protein design)
  • Optogenetics
  • Neurobiology
  • Knock-out mouse colony breeding and animal handling

Interested candidates should send a CV, cover letter and contact information for 3 references.

Mikel Garcia-Marcos, PhD.  mikel.garcia.marcos@gmail.com