• Title Research Associate Professor
  • Education PhD: University of Mannitoba
    Postdoctoral training: Boston University School of Medicine
  • Office 670 Albany Street 5th Fl
  • Phone 617-358-2420
  • Area of Interest mass spectrometry, proteomics, biomarkers, post-translational modifications, PTMs, bioinformatics

Dr. McComb is a Research Associate Professor of Biochemistry at Boston University School of Medicine (BUSM) and is a faculty member of the BUSM Center for Biomedical Mass Spectrometry (CBMS). Dr. McComb has authored/co-authored more than 50 peer-review publications, reviews and textbook chapters and has over 200 conference proceedings including many as invited speaker. Dr. McComb has served as a panel member on several National committees, has served on several NIH peer review study sections and is an expert reviewer for NIH, NCI and other organizations. Dr. McComb is an active member of the Human Proteome Organization (HUPO) whose mission is to characterize the entire human proteome. Dr. McComb’s research aims are directed towards the identification and characterization of differentially expressed proteins and differentially observed peptides and post-translational modifications (PTMs) associated with markers of human disease with an emphasis directed towards cancer and cardiovascular disease. His laboratory focuses on applying mass spectrometry-based proteomics technology for the identification and characterization of proteins which may be perturbed by disease mechanism in-vivo with the aim to identify patterns of changes and PTM events in order to gain a global comprehensive understanding of disease progression. Identification of specific proteins and PTMs which change as a function of disease will lead to the development of diagnostic and prognostic biomarkers which will have tremendous clinical utility.

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