My research career began at Loyola University of Chicago where I majored in biochemistry. As a Women in Science Engaging Research (WISER) fellow, I worked in the lab of Dr. Ken Olsen researching hemoglobin based blood substitutes. After my undergraduate degree, I pursed a master’s degree in kinesiology from the University of Central Florida researching the role of IL-6 on the AKT pathways in rotentone models of Parkinson’s disease.
My goal as a researcher has always been to integrate basic and applied science to better serve the ideas of exercise/nutritional interventions while developing preventative approaches to human disease. With my goals in mind, I joined the lab of Dr. Matt Layne as a Ph.D. student in the summer of 2022 where I focus on fibrosis, mechanical stiffness, and intracellular signaling of adipose tissue.
Publications
Seibel AJ, Frosti CL, Tlemcani AR, Lahiri N, Brammer-DePuy JA, Layne MD, Tien J. Obesity-Associated Conditions Hinder Solute Drainage Function of Engineered Human Lymphatic Vessels. Cellular and Molecular Bioengineering 23 Jan 2025. in press
Wells AJ, Varanoske AN, Coker NA, Kozlowski GJ, Gepner Y, Frosti CL, Boffey D, Harat I, Hoffman JR. (2020). Changes in cognition during a 24-h simulated military operation. Role of classical monocytes and beta- alanine. Medicine & Science in Sports and Exercise. 52(5): S522. DOI: 10.1249/01.mss.0000682348.93835.38
Wells AJ, Varanoske AN, Kozlowski G, Frosti CL, Boffey D, Coker NA, Harat I, Jahani S, Gepner Y, Hoffman JR. (2020). The effect of β-alanine supplementation on monocyte recruitment and cognition during a 24-h simulated military operation (SUSOP). Journal of Strength & Conditioning Research. DOI: 10.1519/JSC.0000000000003809
Varanoske, A.N., Wells, A.J., Boffey, D., Harat, I., Frosti, C.L., Kozlowski, G., Gepner, Y. & Hoffman, J.R. (2020). The effects of high-dose, short-duration β-alanine supplementation on cognitive function, mood, and circulating brain-derived neurotropic factor (BDNF) in recreationally active males before military operational stress. Journal of Dietary Supplements. 6:1-22. DOI: 10.1080/19390211.2020.1733730.
Varanoske, A.N., Wells, A.J., Kozlowski, G.J., Gepner, Y., Frosti, C.L., Boffey, D., Coker, N.A., Harat, I., & Hoffman, J.R. (2018). Effects of β-alanine supplementation on physical performance, cognition, endocrine function, and inflammation during a 24-hr simulated military operation. Physiology Reports. 6(24): e13938. DOI: 10.14814/phy2.13938.
David Boffey, Idan Harat, Cheyanne L Frosti, Yftach Gepner, Shany Funk, Jay R.
Hoffman. (2018). The Physiology and Biomechanics of Load Carriage Performance. Military Medicine. 184(1-2): e83-e90. DOI: 10.1093/milmed/usy218.
Webster, K. D., Dahhan, D., Otto, A. M., Frosti, C.L., Dean, W. L., Chaires, J. B.
and Olsen, K. W. (2017). “Inside-Out” PEGylation of Bovine β-Cross-Linked Hemoglobin. Artificial Organs. 41(4):351-358. DOI: 10.1111/aor.12928.