My research career began at Loyola University of Chicago where I majored in biochemistry. As a Women in Science Engaging Research (WISER) fellow, I worked in the lab of Dr. Ken Olsen researching hemoglobin based blood substitutes. After my undergraduate degree, I pursed a master’s degree in kinesiology from the University of Central Florida researching the role of IL-6 on the AKT pathways in rotentone models of Parkinson’s disease.
My goal as a researcher has always been to integrate basic and applied science to better serve the ideas of exercise/nutritional interventions while developing preventative approaches to human disease. With my goals in mind, I joined the lab of Dr. Matt Layne as a Ph.D. student in the summer of 2022 where I focus on fibrosis, mechanical stiffness, and intracellular signaling of adipose tissue.
Publications
- Frosti CL, Connelly SP, Layne MD. Mechanobiology of Adipose Tissue Remodeling. Tissue Engineering, Part A. 2025. in press.
- Seibel AJ, Frosti CL, Tlemcani AR, Lahiri N, Brammer-DePuy JA, Layne MD, Tien J. Obesity-Associated Conditions Hinder Solute Drainage Function of Engineered Human Lymphatic Vessels. Cell Mol Bioeng. 2025 Jan 23;18(1):53-69. doi: 10.1007/s12195-024-00840-z.
- Wells AJ, Varanoske AN, Coker NA, Kozlowski GJ, Gepner Y, Frosti CL, Boffey D, Harat I, Hoffman JR. (2020). Changes in cognition during a 24-h simulated military operation. Role of classical monocytes and beta- alanine. Medicine & Science in Sports and Exercise. 52(5): S522. DOI: 10.1249/01.mss.0000682348.93835.38
- Wells AJ, Varanoske AN, Kozlowski G, Frosti CL, Boffey D, Coker NA, Harat I, Jahani S, Gepner Y, Hoffman JR. (2020). The effect of β-alanine supplementation on monocyte recruitment and cognition during a 24-h simulated military operation (SUSOP). Journal of Strength & Conditioning Research. DOI: 10.1519/JSC.0000000000003809
- Varanoske, A.N., Wells, A.J., Boffey, D., Harat, I., Frosti, C.L., Kozlowski, G., Gepner, Y. & Hoffman, J.R. (2020). The effects of high-dose, short-duration β-alanine supplementation on cognitive function, mood, and circulating brain-derived neurotropic factor (BDNF) in recreationally active males before military operational stress. Journal of Dietary Supplements. 6:1-22. DOI: 10.1080/19390211.2020.1733730.
- Varanoske, A.N., Wells, A.J., Kozlowski, G.J., Gepner, Y., Frosti, C.L., Boffey, D., Coker, N.A., Harat, I., & Hoffman, J.R. (2018). Effects of β-alanine supplementation on physical performance, cognition, endocrine function, and inflammation during a 24-hr simulated military operation. Physiology Reports. 6(24): e13938. DOI: 10.14814/phy2.13938.
- David Boffey, Idan Harat, Cheyanne L Frosti, Yftach Gepner, Shany Funk, Jay R. Hoffman. (2018). The Physiology and Biomechanics of Load Carriage Performance. Military Medicine. 184(1-2): e83-e90. DOI: 10.1093/milmed/usy218.
- Webster, K. D., Dahhan, D., Otto, A. M., Frosti, C.L., Dean, W. L., Chaires, J. B. and Olsen, K. W. (2017). “Inside-Out” PEGylation of Bovine β-Cross-Linked Hemoglobin. Artificial Organs. 41(4):351-358. DOI: 10.1111/aor.12928.
