Nelson Ruiz-Opazo, M.D.
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Trainees will be involved in rat model of polygenic hypertension, such as the Dahl S rat model, to identify susceptibility genes for polygenic hypertension. These studies also involved gender specific analyses using F2-intercross cohorts for both males and females and 24-hour, non-stress, radiotelemetric measurements of blood pressure. Trainees will pursue ongoing results from total genome scans that have identified gender-specific quantitative trait loci for hypertension and its sequelae.