David Y. Chung, MD, PhD

  • Education Medical School: Columbia University College of Physicians and Surgeons (2010)
    Internship: Internal Medicine, Columbia NewYork-Presbyterian (2011)
    Residency: Neurology, Columbia NewYork-Presbyterian (2014)
    Fellowship: Neurocritical Care, Harvard, Massachusetts General Hospital, and Brigham and Women’s Hospital (2016)

Board Certifications: Neurology and Neurocritical Care
Special Interests: cerebral aneurysms, stroke, traumatic brain injury, neuromonitoring

Publications:

Chung DY, Olson DM, John S, Mohamed W, Kumar MA, Thompson BB, Rordorf GA. Evidence-Based Management of External Ventricular Drains. Curr Neurol Neurosci Rep. 2019 Nov 26; 19(12):94. 

Balkaya M, Seidel JL, Sadeghian H, Qin T, Chung DY, Eikermann-Haerter K, van den Maagdenberg AMJM, Ferrari MD, Ayata C. Relief Following Chronic Stress Augments Spreading Depolarization Susceptibility in Familial Hemiplegic Migraine Mice. Neuroscience. 2019 Sep 01; 415:1-9. 

Takizawa T, Qin T, Lopes de Morais A, Sugimoto K, Chung JY, Morsett L, Mulder I, Fischer P, Suzuki T, Anzabi M, Böhm M, Qu WS, Yanagisawa T, Hickman S, Khoury JE, Whalen MJ, Harriott AM, Chung DY, Ayata C. Non-invasively triggered spreading depolarizations induce a rapid pro-inflammatory response in cerebral cortex. J Cereb Blood Flow Metab. 2019 Jun 26; 271678X19859381. 

Xie H, Chung DY, Kura S, Sugimoto K, Aykan SA, Wu Y, Sakadžic S, Yaseen MA, Boas DA, Ayata C. Differential effects of anesthetics on resting state functional connectivity in the mouse. J Cereb Blood Flow Metab. 2019 May 15; 271678X19847123.

Böhm M, Chung DY, Gómez CA, Qin T, Takizawa T, Sadeghian H, Sugimoto K, Sakadžic S, Yaseen MA, Ayata C. Neurovascular coupling during optogenetic functional activation: Local and remote stimulus-response characteristics, and uncoupling by spreading depression. J Cereb Blood Flow Metab. 2019 May 07; 271678X19845934. 

 Harriott AM, Takizawa T, Chung DY, Chen SP. Spreading depression as a preclinical model of migraine. J Headache Pain. 2019 May 02; 20(1):45. 

Rao SS, Chung DY, Wolcott Z, Sheriff F, Khawaja AM, Lee H, Guanci MM, Leslie-Mazwi TM, Kimberly WT, Patel AB, Rordorf GA. Intermittent CSF drainage and rapid EVD weaning approach after subarachnoid hemorrhage: association with fewer VP shunts and shorter length of stay. J Neurosurg. 2019 Apr 26; 1-6. 

Chung DY, Sadeghian H, Qin T, Lule S, Lee H, Karakaya F, Goins S, Oka F, Yaseen MA, Houben T, Tolner EA, van den Maagdenberg AMJM, Whalen MJ, Sakadžic S, Ayata C. Determinants of Optogenetic Cortical Spreading Depolarizations. Cereb Cortex. 2019 03 01; 29(3):1150-1161. 

Oka F, Chung DY, Suzuki M, Ayata C. Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: Experimental-Clinical Disconnect and the Unmet Need. Neurocrit Care. 2019 Jan 22. 

Chung DY, Sugimoto K, Fischer P, Böhm M, Takizawa T, Sadeghian H, Morais A, Harriott A, Oka F, Qin T, Henninger N, Yaseen MA, Sakadžic S, Ayata C. Real-time non-invasive in vivo visible light detection of cortical spreading depolarizations in mice. J Neurosci Methods. 2018 11 01; 309:143-146. 

Sadeghian H, Lacoste B, Qin T, Toussay X, Rosa R, Oka F, Chung DY, Takizawa T, Gu C, Ayata C. Spreading depolarizations trigger caveolin-1-dependent endothelial transcytosis. Ann Neurol. 2018 09; 84(3):409-423. 

Bouley J, Chung DY, Ayata C, Brown RH, Henninger N. Cortical Spreading Depression Denotes Concussion Injury. J Neurotrauma. 2019 Apr 01; 36(7):1008-1017. 

Chung DY, Mayer SA, Rordorf GA. External Ventricular Drains After Subarachnoid Hemorrhage: Is Less More? Neurocrit Care. 2018 04; 28(2):157-161. 

 Chung DY, Leslie-Mazwi TM, Patel AB, Rordorf GA. Management of External Ventricular Drains After Subarachnoid Hemorrhage: A Multi-Institutional Survey. Neurocrit Care. 2017 Jun; 26(3):356-361. 

Chung DY, Edlow BL. Teaching NeuroImages: Traumatic blown pupil without herniation. Neurology. 2017 05 09; 88(19):e190-e191. 

Chung DY, Ayata C. Spreading Depolarizations. Primer on Cerebrovascular Diseases. ed. Caplan LR, Biller J, Leary MC, Lo EH, Thomas AJ, Yenari M, Zhang JH. 2017; 149-153. 

Chung DY, Oka F, Ayata C. Spreading Depolarizations: A Therapeutic Target Against Delayed Cerebral Ischemia After Subarachnoid Hemorrhage. J Clin Neurophysiol. 2016 Jun; 33(3):196-202. 

Chung DY, Claassen J, Agarwal S, Schmidt JM, Mayer SA. Assessment of Noninvasive Regional Brain Oximetry in Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome. J Intensive Care Med. 2016 Jul; 31(6):415-9. 

Oka F, Hoffmann U, Lee JH, Shin HK, Chung DY, Yuzawa I, Chen SP, Atalay YB, Nozari A, Hopson KP, Qin T, Ayata C. Requisite ischemia for spreading depolarization occurrence after subarachnoid hemorrhage in rodents. J Cereb Blood Flow Metab. 2017 May; 37(5):1829-1840. 

Nelson S, Chung DY, Rordorf G. Recanalization and Remarkable Outcome after Subocclusive Thrombus: A Case Report. J Stroke Cerebrovasc Dis. 2016 Mar; 25(3):e28-30. 

Gutierrez J, Elkind MS, Petito C, Chung DY, Dwork AJ, Marshall RS. The contribution of HIV infection to intracranial arterial remodeling: a pilot study. Neuropathology. 2013 Jun; 33(3):256-63. 

Chung DY, Sampson KJ, Kass RS. Adrenergic regulation and heritable arrhythmias: key roles of the slowly activating heart IKS potassium channel. Heart Rate and Rhythm: Molecular Basis, Pharmacological Modulation and Clinical Implications, ed. Tripathi ON, Ravens U, and Sanguinetti MC. 2011; p451-460. 

Chung DY, Chan PJ, Bankston JR, Yang L, Liu G, Marx SO, Karlin A, Kass RS. Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines. Proc Natl Acad Sci U S A. 2009 Jan 20; 106(3):743-8.

View all profiles