John Farrell – IT Manager
The IT Manager of the Genetics Program leads a team of talented information technology specialists to support the complex computational and data management needs of the Genetics Epidemiology Center and the Molecular Genetics Core Lab. Since arriving at Boston University Medical School in 1981, he has developed software systems and tools for the computerized data collection, data management, quality control and analysis of epidemiological research studies. His efforts have been instrumental in the use of web technologies, optical scanning technologies and laptop computers for the data collection and patient tracking in numerous large scale epidemiological research projects. His recent efforts have included meeting the computational requirements of the Genetics Program research with the installation of a 48-processor Linux Cluster.
Mark McCormack, B.A., Ana Alfirevic, M.D., Ph.D., Stephane Bourgeois, Ph.D., John J. Farrell, M.S., Dalia Kasperavičiūtė, Ph.D., Mary Carrington, Ph.D., Graeme J. Sills, Ph.D., Tony Marson, M.B., Ch.B., M.D., Xiaoming Jia, M.Eng., Paul I.W. de Bakker, Ph.D., Krishna Chinthapalli, M.B., B.S., Mariam Molokhia, M.B., Ch.B., Ph.D., Michael R. Johnson, D.Phil., Gerard D. O’Connor, M.R.C.P.I., Elijah Chaila, M.R.C.P.I., Saud Alhusaini, M.B., Kevin V. Shianna, Ph.D., Rodney A. Radtke, M.D., Erin L. Heinzen, Ph.D., Nicole Walley, B.S., Massimo Pandolfo, M.D., Ph.D., Werner Pichler, M.D., B. Kevin Park, Ph.D., Chantal Depondt, M.D., Ph.D., Sanjay M. Sisodiya, M.D., Ph.D., David B. Goldstein, Ph.D., Panos Deloukas, Ph.D., Norman Delanty, B.M., Gianpiero L. Cavalleri, Ph.D., and Munir Pirmohamed, Ph.D., F.R.C.P. HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans, N Engl J Med 2011; 364:1134-1143, March 24, 2011
John J. Farrell, Richard M. Sherva, Zhi-yi Chen, Hong-yuan Luo, Benjamin F. Chu, Shau Yin Ha, Chi Kong Li, Anselm C.W. Lee, Rever C.H. Li, Chi Keung Li, Hui Leung Yuen, Jason C.C. So, Edmond S.K. Ma, Li Chong Chan, Vivian Chan, Paola Sebastiani, Lindsay A. Farrer, Clinton T. Baldwin, Martin H. Steinberg, and David H.K. Chui. A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression, Blood First Edition Paper, prepublished online March 8, 2011;DOI 10.1182/blood-2010-11-317081[Abstract][PDF][Supplemental Tables and Figures]
Gibney GT, Panhuysen CI, So JC, Ma ES, Ha SY, Li CK, Lee AC, Li CK, Yuen HL, Lau YL, Johnson DM, Farrell JJ, Bisbee AB, Farrer LA, Steinberg MH, Chan LC, Chui DH. Variation and heritability of Hb F and F-cells among beta-thalassemia heterozygotes in Hong Kong. Am J Hematol. 2008 Jun;83(6):458-64.
Ma Q, Wyszynski DF, Farrell JJ, Kutlar A, Farrer LA, Baldwin CT, Steinberg MH. Fetal hemoglobin in sickle cell anemia: genetic determinants of response to hydroxyurea. Pharmacogenomics J. 2007 Dec;7(6):386-94. Epub 2007 Feb 13.
Adewoye AH, Nolan VG, Ma Q, Baldwin C, Wyszynski DF, Farrell JJ, Farrer LA, Steinberg MH. Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia. Clin Infect Dis. 2006 Sep 1;43(5):593-8. Epub 2006 Jul 14.
Nolan VG, Adewoye A, Baldwin C, Wang L, Ma Q, Wyszynski DF, Farrell JJ, Sebastiani P, Farrer LA, Steinberg MH. Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway. Br J Haematol. 2006 Jun;133(5):570-8.
Nolan VG, Baldwin C, Ma Q, Wyszynski DF, Amirault Y, Farrell JJ, Bisbee A, Embury SH, Farrer LA, Steinberg MH. Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia. Br J Haematol. 2005 Jan;128(2):266-72.
Yip A, Ma Q, Wilcox M, Panhuysen CI, Farrell J, Farrer LA, Wyszynski DF. Search for genetic factors predisposing to atherogenic dyslipidemia. BMC Genetics 2003, 4(Suppl 1):S100 (1 December 2003)
Wilcox MA, Wyszynski DF, Panhuysen CI, Ma Q, Yip A, Farrell J, Farrer LA. Empirically derived phenotypic subgroups – qualitative and quantitative trait analyses. BMC Genetics 2003, 4(Suppl 1):S15 (1 December 2003)
Web- Based Medication Reference Database for Researchers, J. J. Farrell, AMIA 1996 Annual Symposium.
The Drug Etiology of Agranulocytosis and Aplastic Anemia Kaufman, Kelly, Levy, Shapiro, and Study Group, 1991.
A Data Collection And Coding System On A Portable Computer For Epidemiological Studies. , J. J. Farrell, 11th Symposium on Computer Applications in Medical Care, 1987.
Identification Of Antibiotic-Inactivating Enzymes By Stepwise Discriminant Analysis of Susceptibility Test Results, R. L. Kent, T. F. O’Brien, A. A. Medieros, J. J. Farrell, and M.A. Guzman, Current Chemotherapy and Infectious Disease, Proceedings of the 11th ICC and 19TH ICAAC, American Society of Microbiology, 1980.