Research focuses on studying the role of inflammation on aortic smooth muscle cell function. A major focus has been studying the impact of acute phase serum amyloid A on the development of atherosclerosis. Most recently, efforts have been directed at evaluating the role of periodontal disease on the vasculature with an eye toward poor birth outcomes.
Dr. Schreiber is also the director of the Program in Biomedical Sciences (PiBS), director of graduate studies in the Biochemistry department, co-PI on the BU’s BEST (Boston University’s Boston University Broadening Experiences in Scientific Training) award and PI on TOTAL (Training Opportunities To Augment Learning).
Representative Publications
- Bolgioni AF, Barbercheck CR, Hokanson SC, Dominguez MI, Spencer JL, Hyman LE, Schreiber, BM. BU’s BEST: Using biomedical workforce data to inform curriculum and influence career exploration. Chapter 1, in BEST: Implementing Career Development Activities for Biomedical Research Trainees. 2020, Academic Press, Eds. Lara, Daniel, and Chalkley.
- Pessolano L, Kramer CD, Simas A, Weinberg EO, Genco CA, Schreiber BM. Periodontal Disease and Birth Outcomes: Are We Missing Something?. Current Oral Health Reports. 7, 62-71(2020). Article
- Davies TA, Kaye E, Stahlberger M, Abbas M, Sarkis C, Reed L, Dunham L, Schreiber BM, Leone C, Mascarenhas AK. Improving Diversity of Dental Students Through the Boston University Master’s of Oral Health Sciences Postbaccalaureate Program. J Dent Educ. 2019 Mar; 83(3):287-295. PMID: 30692183
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Seidl SE, Pessolano LG, Bishop CA, Best M, Rich CB, Stone PJ, Schreiber BM. Toll-like receptor 2 activation and serum amyloid A regulate smooth muscle cell extracellular matrix. PLoS One. 2017; 12(3):e0171711. PMID: 28257481
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Pessolano LG, Sullivan CP, Seidl SE, Rich CB, Liscum L, Stone PJ, Sipe JD, Schreiber BM. Trafficking of endogenous smooth muscle cell cholesterol: a role for serum amyloid A and interleukin-1ß. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2741-50. PMID: 22995521.
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Sullivan CP, Seidl SE, Rich CB, Raymondjean M, Schreiber BM. Secretory phospholipase A2, group IIA is a novel serum amyloid A target gene: activation of smooth muscle cell expression by an interleukin-1 receptor-independent mechanism. J Biol Chem. 2010 Jan 1; 285(1):565-75. PMID: 19850938.
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St Hilaire C, Yang D, Schreiber BM, Ravid K. B-Myb regulates the A(2B) adenosine receptor in vascular smooth muscle cells. J Cell Biochem. 2008 Apr 15; 103(6):1962-74. PMID: 17979185.
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Yang D, Koupenova M, McCrann DJ, Kopeikina KJ, Kagan HM, Schreiber BM, Ravid K. The A2b adenosine receptor protects against vascular injury. Proc Natl Acad Sci U S A. 2008 Jan 15; 105(2):792-6. PMID: 18184815.
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Hurtado PA, Vora S, Sume SS, Yang D, St Hilaire C, Guo Y, Palamakumbura AH, Schreiber BM, Ravid K, Trackman PC. Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation. Biochem Biophys Res Commun. 2008 Feb 1; 366(1):156-61. PMID: 18060869.
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Xu Y, McDonald J, Perloff E, Butticè G, Schreiber BM, Smith BD. Collagen and major histocompatibility class II expression in mesenchymal cells from CIITA hypomorphic mice. Mol Immunol. 2007 Mar; 44(7):1709-21. PMID: 16982097.
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Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD, Ravid K. The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J Clin Invest. 2006 Jul; 116(7):1913-23. PMID: 16823489.
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Nagata Y, Jones MR, Nguyen HG, McCrann DJ, St Hilaire C, Schreiber BM, Hashimoto A, Inagaki M, Earnshaw WC, Todokoro K, Ravid K. Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp Cell Res. 2005 May 1; 305(2):277-91. PMID: 15817153.
Complete list can be found at BU Profiles
