MOLECULAR BIOLOGY, CELL BIOLOGY, DISEASE MECHANISMS
PEOPLE: We are a highly interactive group of faculty, graduate students, and postdoctoral fellows with diverse research interests in biochemistry, cell biology, molecular biology, and genetics. We use cutting-edge technologies and experimental systems to address the cellular and molecular mechanisms of biological processes, particularly those that relate broadly to human disease.
RESEARCH: Research themes include Neuroscience & Aging; Signal Transduction & Cancer; ECM/Cellular Injury; Metabolism, Obesity/Diabetes; Proteomics, Glycomics & Lipidomics; and Development.
GRADUATE STUDY: We are committed to the education of graduate, medical, and dental students. The emphasis of our graduate program is on comprehensive research training in our faculty members’ laboratories. Prospective students can apply to our new interdisciplinary umbrella program called Program in Biomedical Sciences administered through Graduate Medical Sciences.
Spotlight on Research…G proteins and disease
Congratulations to the Garcia-Marcos lab for their recent publication investigating the molecular basis for disease-linked mutations in G proteins. Heterotrimeric G proteins are molecular switches that control signal transduction. Many mutations in G proteins have been shown to cause human diseases. But not all these mutations are made equal. They found that two identical mutations can cause different diseases even if present in highly similar G proteins. By dissecting the biochemical properties of the different mutants, they elucidated the basis of how an identical mutation can make one G protein hyperactive in cancer and the second G protein inactive in rare inherited disease. For more information on their research and publications please visit their lab page: Garcia-Marcos lab.
Spotlight on…Faculty Recuitment
As part of an ongoing expansion program, the Department of Biochemistry at the Boston University School of Medicine invites applications for new faculty positions at the level of Assistant or Associate Professor. We seek creative scientists using cutting-edge technologies and experimental systems to address the cellular and molecular mechanisms of biological processes, particularly those that relate broadly to human disease.
For more Information: Faculty positions For past Spotlights:Archives