MOLECULAR BIOLOGY, CELL BIOLOGY, DISEASE MECHANISMS
PEOPLE: We are a highly interactive group of faculty, graduate students, and postdoctoral fellows with diverse research interests in biochemistry, cell biology, molecular biology, and genetics. We use cutting-edge technologies and experimental systems to address the cellular and molecular mechanisms of biological processes, particularly those that relate broadly to human disease.
RESEARCH: Research themes include Neuroscience & Aging; Signal Transduction & Cancer; ECM/Cellular Injury; Metabolism, Obesity/Diabetes; Proteomics, Glycomics & Lipidomics; and Development.
GRADUATE STUDY: We are committed to the education of graduate, medical, and dental students. The emphasis of our graduate program is on comprehensive research training in our faculty members’ laboratories. Prospective students can apply to our new interdisciplinary umbrella program called Program in Biomedical Sciences administered through Graduate Medical Sciences.
Spotlight on Research…Varelas Lab
Congratulations to the Varelas lab for their recent publication identifying the Hippo pathway as a critical mediator of microRNA (miRNA) biogenesis. MicroRNAs are small double stranded RNA regulators of gene expression that are implicated in most aspects of human development and disease. Deregulation of Hippo pathway signals leads to defects in the maturation of precursor miRNAs into mature and functional miRNAs. Their study provides unexpected insight into the roles of Hippo pathway signaling, providing an important new mechanism for how miRNAs are controlled. Additional information on the Varelas lab, its research, and these publications can be found here: Varelas lab.