CVI Seminar Series

Whitaker Cardiovascular Institute: SEMINAR SERIES

2012-2013
Date: Speaker Name: Academic Title: Affiliation: Title of Talk:
January 10, 2012 Milka Koupenova-Zamor, Ph.D. Postdoctoral Fellow BUSM/U Mass WorcestorRavid/Freedman Labs Toll Like Receptor 7 and Thrombocytopenia
January 17, 2012 Jessica Fry, Ph.D. Postdoctoral Fellow BUSM/Richard Cohen’s Lab Polyphenols, Oxidants, and Sirtuin 1 in Vascular Dysfunction
January 24 2012 Carolyn Kramer, Ph.D Postdoctoral Fellow BUSM/Genco Lab Role of Oxidative Stress in Electrical Remodeling and Arrhythmogenesis: Exploring Targets
in Mouse and Human Models of Disease
January 24, 2012 Klara Rosenquist, Ph.D. Postdoctoral Fellow BUSM/Fox Lab CT Attenuation and Cardiometabolic Risk: Framingham Heart Study
March 13, 2012 Dylan Steen, Ph.D. Postdoctoral Fellow HMS/Wiviott Lab REVEAL HPS3/TIMI55: A 30,000 Patient Phase III Clinical Trial
March 20, 2012 Barbara Kahn, MD George R. Minot Professor of Medicine Beth Israel Deaconess Medical Center “Novel Mechanisms by Which Adipose Cells Sense Glucose and Regulate Systemic Insulin Sensitivity and the Risk for Metabolic Syndrome.”
March 27, 2012 Jessica Fetterman, Ph.D Postdoctoral Fellow BUSM/Vita Lab “Mitochondrial Haplotype and Function in Cardiovascular Disease.”
April 3, 2012 Albert J. Sinusas, MD Professor of Medicine (Cardiology) and of Diagnostic Radiology University of Alabama “Multimodality Imaging of Post-MI Remodeling.”
April 17, 2012 (resched to June 5, 2012) Kenneth Barth, Ph.D. Postdoctoral Fellow BUSM/U Mass WorcestorGenco Lab “Pathogen Induced Cleavage of Receptor Interacting Protein Kinases Impairs Innate Immune Signaling in Endothelial Cells.”
April 24, 2012 David A. Calhoun, MD Associate Professor, Dept Medicine, Division of Cardiovascular Disease University of Alabama “Resistant and Refractory Hypertension: Diverging Phenotypes?”
May 1, 2012 Nathan K. LeBrasseur, Ph.D. Associate Professor of Physical Medicine and Rehabilitation Mayo Clinic, Rochester Minnesota “Skeletal Muscle Loss and the Penalties of Aging.”
May 15, 2012 Antonina Risitano, Ph.D. Postdoctoral Fellow BUSM/U MassFreedman Lab “Platelets and Platelet-Like Particles as Mediators
of Intercellular RNA Transfer”
May 22, 2012 Humra Athar, Ph.D. Postdoctoral Fellow BUSM/McKnight Lab “Structural Studies and Role of Microsomal Triglyceride Transfer Protein (MTP) in the Assembly and Lipidation of ApoB Containing Lipoproteins.”
June 19, 2012 Diane E. Handy, Ph.D. Assistant Professor of Medicine, Cardiology Brigham and Women’s Hospital “Glutathione Peroxidase-1 and Endothelial Cell Activation”
June 26, 2012 Melissa Farb, Ph.D Postdoctoral Fellow BUSM/Gokce Lab “Role of Adipose Tissue Phenotype in Vascular Disease Mechanisms.”
September 18, 2012 Rudy Valentine, Ph.D Postdoctoral Fellow BUSM/Dr. Neil Ruderman “Activation of AMPK Prevents High-Glucose Induced Fetuin-A Release from HepG2 Cells”
October 4, 2012 Peipei Ping, Ph.D Professor, Medicine/Physiology University of California, LosAngeles “Mitochondrial Proteome Dynamics: Evidence Opposing Synchronization”
October 30, 2012 Gary Tearney, Ph.D Professor of Pathology Harvard Medical School
Affiliated Faculty Member
of the Harvard-MIT Division of Health Sciences and Technology
Associate Director of the Wellman Center for Photomedicine at MGH
“The Future of Coronary OCT”
November 13, 2012 Jay Heinecke, Ph.D Professor of Medicine
Division of Metabolism, Endocrinology and Nutrition
University of Washington School of Medicine at SLU
Seattle/Sponsored by MERCK
“Pathways for the Generation of Dysfunctional HDL”
December 4, 2012 Milka Koupenova-Zamor, Ph.D Postdoctoral Fellow Drs. Katya Ravid/BUSM and Jane Freedman/UMass Medical School “Platelet TLR7 and Viral-Thrombocytopenia, A Work-in-Progress Presentation”
December 11, 2012 Gladys Ngoh, Ph.D Postdoctoral Fellow BUSM/Dr. Kenneth Walsh “Role of Mitofusins in Vascular Endothelial Cells, A Work-in-Progress Presentation”
January 8, 2013 Dylan Steen, Ph.D Postdoctoral Fellow Dr. Stephen D. Wiviott
Brigham and Women’s Hospital
BWH/TIMI Study Group
“Use of Intensive Lipid-Lowering Therapy Following an Acute Coronary Syndrome:  Insights from TRITON-TIMI 38A, Work-in-Progress Presentation”
January 15, 2013 Klara Rosenquist, Ph.D Postdoctoral Fellow Dr. Caroline Fox
Director of Metabolic Research, Framingham Heart Study
“Fat Quality Estimatedby Computed Tomography and Its Association with Incident Cardiovascular Disease and All-Cause Mortality, A Work-in-Progress Presentation”
January 22, 2013 Pamela Dorsey, Ph.D Postdoctoral Fellow BUSM/Drs. Joseph Vita and Naomi Hamburg “Effects of Cocoa on Ambulatory Blood Pressure and Vascular Function in Patients with Stage I Hypertension, A Work-in-Progress Presentation”
January 22, 2013 Christine Oslowski, Ph.D Postdoctoral Fellow BUSM/Dr. Victoria Bolotina “Calcium Roots of ER StressA,  Work-in-Progress Presentation”
January 29, 2013 Raj Kishore, Ph.D Associate Professor of Medicine
Associate Professor of Biological Chemistry
and Molecular Pharmacology
Investigator, Feinberg Cardiovascular Research Institute
Northwestern University “Cooling the Inflamed Heart:  Therapeutic Effect of IL-10 on Ischemic Myocardium Repair”
February 21, 2013 David G. Harrison, Ph.D Betty and Jack Bailey Professor of Medicine and Pharmacology
Director, Division of Clinical Pharmacology
Director of the Center for Vascular Biology
Vanderbilt University School of MedicineSeminar Sponsored Jointly by W.C.V.I. and Vascular Biology “Inflammation, Immunity and Hypertension”
March 19, 2013 Carolyn Kramer, Ph.D Postdoctoral Research Fellow BUSM/Dr. Caroline A. Genco “Distinct Gene Signatures Define Pathogen- vs. Fat-Induced Atherosclerosis, A Work-in-Progress Presentation”
March 26, 2013 Jessica Fetterman, Ph.D Postdoctoral Research Fellow BUSM/Dr. Joseph Vita “Impaired Autophagy in Endothelial Cells from Diabetic Patients, A Work-in-Progress Presentation”
April 2, 2013 Susan MacLauchlan, Ph.D Postdoctoral Research Fellow BUSM/Dr. Kenneth Walsh “Wnt5a-Regulated Splicing of Anti-Angiogenic VEGFA165b”,
A Work-in-Progress Presentation
April 23, 2013 Mark Hargreaves, Ph.D Professor, Department of Physiology, Pro Vice-Chancellor (Research Partnerships) The University of Melbourne, Australia “Exercise and GLUT4 Expression”
April 30, 2013 Richard Lee, Ph.D Professor of Medicine Cardiovascular Disease Program
Harvard Stem Cell Institute
“Cardiomyocyte Regeneration in Mammals”
May 7, 2013 John P. Cooke, Ph.D Director, Section on Vascular Medicine Stanford University School of Medicine “Vascular Regeneration and the Role of Innate Immunity in Nuclear Reprogramming”
May 21, 2013 Humra Athar, Ph.D Postdoctoral Research Fellow BUSM “Early Events in the Assembly and Lipidation of ApoB-Containing Lipoprotein Particles, A Work-in-Progress Presentation”
June 4, 2013 Heidi Schwanz, Ph.D Postdoctoral Research Fellow BUSM “In Vivo MR Imaging of Atherosclerotic Plaques with Activatable Cell-Penetrating Peptides (ACPPs) Targeting Thrombin”, A Work-in-Progress Presentation
June 18, 2013 Thomas M. Coffman, M.D. James R. Clapp Professor
of Medicine
Chief, Division of Nephrology
Program Director in Cardiovascular and Metabolic Disorders
Duke University
Medical Center
Durham, NC
“Vascular Actions of AT1 Angiotensin Receptors in Hypertension”
June 25, 2013 Vipul Chitalia, M.D., Ph.D. Assistant Professor Renal Section Boston University School of Medicine Boston, MA “The Role of Uremic Solutes in Vascular Thrombosis”
September 17, 2013 Ira A. Tabas, M.D., Ph.D. Richard J. Stock Professor and Vice-Chairman of Research Columbia University College of Physicians and Surgeons New York, NY “Defective Inflammation Resolution and Atherosclerosis: Mechanisms and Therapeutic Opportunities”
September 24, 2013 Edward A. Fisher, M.D., Ph.D. Leon H. Charney Professor of Cardiovascular Medicine Director, Marc and Ruti Bell Program in Vascular Biology New York University School of Medicine New York, NY “Regression of Atherosclerosis: Out with the Old, In with the New”
October 1, 2013 Dwight A. Towler, M.D., Ph.D. Professor, Diabetes and Obesity Research Center Sanford-Burnham Medical Research Institute Orlando, FL “The Biology and Physiology of Diabetic Arteriosclerosis: Endocrine Regulation of an Inflammatory ‘Wnt-opathy’”
 October 8, 2013 David A. Goukassian, M.D., Ph.D. Associate Professor of Medicine Principal Investigator, CardioVascular Systems Biology Center for Biomedical Research Tufts University School of Medicine and St. Elizabeth’s Medical Center Boston, MA “Cardiovascular Challenges for Future Human Exploration:  Type Moon, Near Earth Asteroid and Mars Missions”
October 29, 2013 Bradley S. Fleenor, Ph.D. Assistant Professor Kinesiology and Health Promotion University of Kentucky Lexington, KY “Periaortic Adipose and Large Artery Stiffness”
November 12, 2013 Roger J. Hajjar, M.D. Director, Cardiovascular Research Center Arthur & Janet C. Ross Professor of Medicine Icahn School of Medicine at Mount Sinai New York, NY “Small Changes/Big Impact:  The Role of SERCA2a Modifications in Heart Failure”
November 19, 2013 Joyce J. Repa, Ph.D. Associate Professor University of Texas Southwestern Medical Center Dallas, TX “Nuclear Hormone Receptor Regulation of Cholesterol Homeostatis”
December 10, 2013 Edward G. Lakatta, M.D. Senior Investigator Chief, Laboratory of Cardiovascular Science National Institute on Aging Baltimore, MD “The Stress of Aging Viewed from the Arterial Wall”
December 17, 2013 Douglas B. Sawyer, M.D., Ph.D. Professor of Medicine and Pharmacology Vanderbilt University Nashville, TN “Mining Ontogeny for Cardiovascular Therapeutics — the Neuregulin Story

 

2010-2011
Date: Speaker Name: Academic Title: Affiliation: Title of Talk:
September 28, 2010 Jane E. Freedman, M.D. Professor of Medicine,
Pharmacology and Experimental Therapeutics
Boston UniversitySchool of MedicineBoston, MA Gene Expression
and Cardiovascular Disease: Bridging Basic Science and the Framingham Heart Study
October 4, 2010 Pavlos Pissios, Ph.D. Instructor in Medicine Division of Endocrinology, Diabetes and Metabolism
Harvard Medical School and Beth Israel-Deaconess Medical Center
Regulation of Glucose and Lipid Metabolism by Nicotinamide
N-methlytransferase
October 19, 2010 Michael J. Mazzini, M.D. Instructor in Medicine Cardiac Electrophysiology
and Arrhythmia Service
Boston University
School of Medicine
Boston, MA
Role of Oxidative Stress in Electrical Remodeling and Arrhythmogenesis: Exploring Targets
in Mouse and Human Models of Disease
October 19, 2010 Edward J. Miller, M.D., Ph.D. Assistant Professor
of Medicine
and Radiology
Boston University
School of Medicine
Boston, MA
The Role and Regulation of AMPK in Diabetic Cardiomyopathy
October 26, 2010 Carlos M. Ferrario, M.D. Professor Wake Forest University
School of Medicine
Winston-Salem, NC
A Biological Trilogy within the RAS: Angiotensin – (1-12), ACE2 and ANG-(1-7)
November 3, 2010 Jennifer L. Hall, Ph.D. Director, Program
in Translational Genomics, Lillehei Heart Institute
Associate Professor
of Medicine
University of Minnesota, Minneapolis, MN Heparan-sulfate Dependent Modulation
of the Vasculature
November 30, 2010 Noyan Gokce, M.D. Associate Professor
of Medicine,
Director
of Echocardiography
Boston University
School of Medicine
Boston, MA
Adipose Phenotypes
and Vascular Dysfunction in Obesity
December 7, 2010 Ivor J. Benjamin, M.D. Christi Smith Professor and
Chief, Division
of Cardiology
University of Utah School of Medicine
Salt Lake City, UT
Oxido-reductive Stress Signaling Networks: New Targets in Heart Diseases
December 14, 2010 Aruni Bhatnagar, Ph.D. Professor of Medicine and Distinguished University Scholar University of Louisville,
Louisville, KY
Lipid Oxidation Products and Cardiovascular Disease
January 25, 2011 Joseph E. Italiano, Ph.D. Assistant Professor
of Medicine
Division of Translational Medicine,
Brigham and Women’s Hospital,
Department of Vascular Biology, Children’s Hospital,
Boston, MA
New Mechanisms
of Blood Platelet Production
January 28, 2011 You-Yang Zhao, Ph.D. Assistant Professor Department
of Pharmacology
and Center for Lung and Vascular Biology
University of Illinois
Chicago
The Requisite Role
of FoxM1 in Regulating Endothelial Regeneration
and Repair Following Vascular Injury
Faculty Candidate
February 1, 2011 Daniel G. Remick, M.D. Professor and Chairman,
Pathology
and Laboratory Medicine
Boston University
School of Medicine
Boston, MA
Sepsis, Bad for You
and Your Heart
February 8, 2011 Andrew S. Weyrich, Ph.D. Program in Human Molecular Biology
and Physics
University of Utah School of Medicine
Salt Lake City, UT
New Functions
of Platelets
in Thrombosis
and Inflammation
February 15, 2011 Lucy Liaw, Ph.D. Research Scientist Center for Molecular Medicine, Maine Medical Center Research Institute Smooth Muscle Cell Integration
of Differentiation Signals
March 1, 2011 Christopher P. Baines, Ph.D. Assistant Professor Dalton Cardiovascular Research Center,
University of Missouri
Columbia, MO
RIPping Holes
in Mitochondria: Is Necrosis Programmed?
March 4, 2011 David Cormode, Ph.D. Postdoctoral Fellow Translational
and Molecular Imaging Institute
Mount Sinai School
of Medicine
New York
Molecular Imaging
of Cardiovascular Disease
with Lipid-Coated Nanoparticles
Faculty Candidate
March 8, 2011 Lisa A. Cassis, Ph.D. Professor and Chair Graduate Center
for Nutritional Sciences
University of Kentucky
The Renin-Angiotensin System in Obesity
and Vascular Diseases
March 15, 2011 Kathleen Morgan, Ph.D. Professor and Chair
Department of Health Sciences,
Senior Scientist, Boston Biomedical Research Institute,
Director, Cytoskeleton
& Signaling Lab.
Sargent College
of Health
& Rehabilitation Sciences,
Boston University
Boston, MA
Cytoskeletal Biology, Aortic Stiffness
and Cardiovascular Disease: A Connection?
March 29, 2011 Dan E. Berkowitz, M.B.BCh. Professor Anesthesiology & Critical Care Medicine
and
Biomedical Engineering
The Johns Hopkins University School
of Medicine
Nitroso-Redox Balance, Aging and Vascular Stiffness: Why It Matters
April 5, 2011 Kaikobad Irani, M.D. Associate Professor
of Medicine
Department
of Pharmacology
and Chemical Biology,
University of Pittsburgh,
Pittsburgh, PA
Vascular Targets
of Lysine Acetylation: Mechanisms and Consequences
April 19, 2011 Caroline A. Genco, Ph.D. Professor
and Research Director
Section of Infectious Diseases
Professor
Department of Medicine
Section of Infectious Diseases
Department
of Microbiology
Infection
and Inflammation
Take Their “Toll”
on Atherosclerosis
April 26, 2011 Jessica L. Fry, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston University
School of Medicine
Boston, MA
Systems to Evaluate
the Regulation of SIRT1 Activity by Oxidative Post-Translational Modifications
A Work-in-Progress Presentation
May 2, 2011 Da-Zhi Wang, Ph.D. Associate Professor Cardiovascular Research Division
Children’s Hospital
Harvard Medical School
Boston, MA
miRNAs in Heart
and Skeletal Muscle
In Conjunction with
The Center
for Nanoscience
and Nanobiotechnology
May 3, 2011 William C. Sessa, Ph.D. Professor Department
of Pharmacology,
Yale University School
of Medicine
New Haven, CT
A Cell Biological Approach to Vascular Signaling and Function
May 17, 2011 Eric Essick, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston University
School of Medicine
Boston, MA
Adiponectin: Protection Against Oxidative
Stress-Induced Adverse Cardiac Remodeling
A Work-in-Progress Presentation
June 7, 2011 Kenneth Barth, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston University
School of Medicine
Boston, MA
Pathogen Induced Cleavage of Receptor Interacting Protein Kinase 2 in Endothelial Cells is Mediated
by a Lysine-Specific Cysteine Proteinase
A Work-in-Progress Presentation
June 14, 2011 Heather S. Duffy, Ph.D. Assistant Professor
of Medicine
Harvard Medical School
Beth Israel/Deaconess Medical Center
Center for Life Sciences
Boston, MA
Myocyte to Fibroblast Cross Talk in the Heart: Role of an ATP Channel in Fibrosis
June 28, 2011 Humra Athar, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston University
School of Medicine
Boston, MA
Early Events
in the Formation
and Secretion of Very Low Density Lipoprotein,
the Precursor of LDL
A Work-in-Progress Presentation
June 28, 2011 Melissa Farb, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston University
School of Medicine
Boston, MA
The Role of Adipose Tissue Phenotype
in Vascular Disease Mechanisms
A Work-in-Progress Presentation
June 29, 2011 Khalid Matrougui, Ph.D., F.A.H.A. Associate Professor Department
of Physiology
Tulane University School of Medicine
New Orleans, LA
Regulatory T Cells
and Microvascular Dysfunction in Hypertension
Faculty Candidate
July 29, 2011 Isabelle Deschenes, Ph.D. Associate Professor Physiology
and Biophysics and Biomedical Engineering
Heart & Vascular Research Center
MetroHealth Medical Center
Case Western Reserve University
Cleveland, OH
Sodium Channels
and Arrhythmias
Faculty Candidate
September 26, 2011 Paul J. Marvar, Ph.D. Research Fellow Scholars Program
in Interdisciplinary Neuroscience
Emory University
Atlanta, GA
Neural Regulation
of Blood Pressure
and T Lymphocytes
in Stress-Dependent Hypertension
Faculty Candidate
September 27, 2011 Edward A. Fisher, M.D., M.P.H., Ph.D. Professor New York University School of Medicine The Regression
of Atherosclerosis: Roles of HDL
November 8, 2011 Jay Horton, M.D. Professor University of Texas Southwestern Medical Center, Dallas, TX TUpdate of PCSK9:
A Post-Transcriptional Regulator of Hepatic LDL Receptors
and Plasma LDL-Cholesterol
2009-2010
Date: Speaker Name: Academic Title: Affiliation: Title of Talk:
January 6, 2009 Francisco Jose Naya, Ph.D. Assistant Professor, Department of Biology; Member, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA Requirement of the MEF2 Target Gene Myomaxinin Angiotension II Induced Cardiomyopathy
January 13, 2009 George Liang King, M.D. Professor of MedicineAnd Director of Research Harvard Medical School andJoslin Diabetes CenterBoston, MA Is Insulin’s Actions on the Endothelium Anti-Atherogenicor Pro-Atherogenic?
January 20, 2009 Arya Mani, M.D. Director, Cardiovascular Module Yale UniversitySchool of MedicineNew Haven, CT A Single Gene at the Crossroadsof Metabolic Phenotypes
January 27, 2009 Hongjie Chen, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA Regulation of Tumor Necrosis Factor-Alpha Production by the A2B Adenosine Receptor in MacrophagesA Work-in-Progress Presentation
January 27, 2009 Eric Essick, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA Adiponectin:  Potential Cardioprotection Against Oxidative Stress and Cardiac RemodelingA Work-in-Progress Presentation
February 2, 2009 Christian Kupatt, M.D. Assistant Professor, Internal Medicine I – Interventional Cardiology Ludwig Maximilians UniversityMunich, German Role of AKT in Vascular Remodeling of Ischemic Tissue
February 3, 2009 Charles N. Serhan, Ph.D. Simon Gelman Professor of Anaesthesia, Department of Anaesthesiology, Perioperative & Pain Medicine; Director, Center for Experimental Therapeutics and Reperfusion Injury Harvard Medical SchoolBrigham & Women’s HospitalBoston, MA A Systems Approach to Acute Inflammation Reveals a New Genus of Anti-Inflammatory and Pro-Resolving Mediators:  Resolvins and Protectins
February 6, 2009 P. Christian Schulze, M.D., Ph.D. Clinical Fellowin Cardiology New York Presbyterian HospitalColumbia University Medical Center Myocardial and Skeletal Muscle Metabolism and Proteolysis in Heart Failure
February 24, 2009 Joseph A. Hill, M.D., Ph.D. James T. Willerson, M.D. Distinguished Chair in Cardiovascular Diseases; Frank M. Ryburn, Jr. Chairin Heart Research; Director, Harry S. Moss Heart Center; Professor of Internal Medicine and Molecular Biology University of Texas Southwestern Medical Center,Dallas, TX Pathological Cardiac Remodeling:  Mechanisms and Therapies
March 4, 2009 Christopher Maack, M.D. Klinik fur Innere Medizin III Universitatsklinikum des SaarlandesHomberg, Germany Cardiac Mitochondria and EC Coupling
March 5, 2009 Ariel Escobar, Ph.D. Professor School of EngineeringUniversity of CaliforniaMerced, CA Subcellular Basis of Cardiac Arrhythmias
March 1 0, 2009 Monty Krieger, Ph.D. Whitehead Professor of Biology Massachusetts Institute of TechnologyCambridge, MA Charting the Fate of the ‘Good Cholesterol’ – Characterizationof the HDL Receptor SR-B1 and Its Influence on Coronary Heart Disease
March 17, 2009 Robert A. Gottlieb, M.D. Director, SDSU Bioscience Center; Frederick G. Henry Endowed Chairin the Life Sciences;Professor of Biology San Diego State UniversitySan Diego, CA Eat Your Heart Out:  Role of Autophagy in Cardioprotection
March 19, 2009 Toren Finkel, M.D., Ph.D. Chief, Translational Medicine Branch National Institutesof HealthNational Heart, Lung & Blood InstituteBethesda, MD Sirtuins, Autophagy and Mitochondrial Homeostasis
March 24, 2009 Dean Thomas Michel, Ph.D., M.D. Federman Chairin Medical Education; Professor of Medicine and Biochemistry; Dean for Education; Senior Physicianin Cardiovascular Medicine Harvard Medical SchoolBrigham & Women’s HospitalBoston, MA Nitric Oxide Syntheses and Cardiovascular Signaling
March 31, 2009 Mark Sussman, Ph.D. Distinguished Professor of Biology SDSU Heart InstituteSan Diego, CA PIM-1 Kinase Revealed:  A New Chapter in Myocardial Survival Signaling
April 7, 2009 Lea Beaulieu, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA Inflammatory Modulationof Megakaryocyte Cell Function A Work-in-Progress Presentation
April 7, 2009 Bo Yang, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA New Determinants of Proliferation and Migrationof Vascular Smooth Muscle CellsA Work-in-Progress Presentation
April 14, 2009 Ji Li, Ph.D. Director, Centerfor Cardiovascular Research and Alternative Medicine; Assistant Professor of Pharmacology and Physiology University of WyomingSchool of PharmacyLaramie, WY Age-Associated Reduction in Ischemic AMPK Activiation
April 21, 2009 Reto Asmis, Ph.D. Director of Research Development; Associate Professor University of Texas Science CenterSan Antonio, TX Thio Redox Signaling in Macrophage Dysfunction and Atherosclerosis
April 28, 2009 Michael C. Carroll, Ph.D. Director, Graduate Program in ImmunologyProfessor of Pediatrics Harvard Medical SchoolChildren’s HospitalBoston, MA Oxidative Stress Induces an Innate Response to Self-Tissues
May 5, 2009 Jesse Lugus, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA Skeletal Muscle as a Signaling Node:  Discovery and Validation of Novel Myokines
May 5, 2009 Duncan Sousa, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA Tropomyosin Flexibility Evaluated by Electron Microscopy Image Analysis
May 13, 2009 David G. Harrison, Ph.D. Director, Divisionof Cardiology; Professor of Medicine Emory University School of MedicineAtlanta, GA Regulation of Tetrahydrobiopterin by Shear Stress
June 2, 2009 Roger Hajjar, M.D. Research Director of Mount Sinai’s Wiener Family Cardiovascular Laboratories; Arthur and Janet C. Ross Professor of Medicine; Professor, Gene and Cell Medicine Mount Sinai School of MedicineNew York, NY Targeting Calcium Cycling in Heart Failure
June 9, 2009 Ernest Schaefer, M.D. Jean Mayer USDA HNRCA at Tufts University Tufts UniversityNew England Medical CenterBoston, MA Function and Metabolism of HDL Particles
June 16, 2009 Richard T. Lee, M.D. Harvard Medical SchoolBrigham & Women’s Hospital, Boston;Partners Research Facility,Cambridge, MA Cardiomyocyte Refreshment and Regeneration
June 23, 2009 Xuebin Qin, Ph.D., M.D. Assistant Professor of Medicine Harvard Medical School; Laboratory for Translational ResearchCambridge, MA Complement Regulator CD59 in Vascular Diseases
September 22, 2009 Sarah Haigh Molina, Ph.D. Director of Screening High Throughput Screening CoreCore Laboratories and Facilities Boston UniversitySchool of MedicineBoston, MA Using the High Throughput Screening (HTS) Facility to Enhance and Advance Your Research
September 29, 2009 Roger Hajjar, M.D. Research Director of Mount Sinai’s Wiener Family Cardiovascular Laboratories; Arthur and Janet C. Ross Professor of Medicine; Professor, Gene and Cell Medicine Mount Sinai School of MedicineNew York, NY Targeting Calcium Cycling in Heart Failure:  from Basic Mechanisms to Clinical Trials
October 6, 2009 Lorrie Kirshenbaum, Ph.D. Professor, Departmentof Pharmacologyand Therapeutics & Department of Physiology; Principal Investigator, Cardiac Gene Biology, Institute of Cardiovascular Sciences University of ManitobaWinipeg, MB Molecular Regulation of Apoptosis in the Heart
October 27, 2009 Clay F. Semenkovich, M.D. Herbert S. Gasser Professor; Chief, Division of Endocrinology, Metabolism & Lipid Research Washington UniversitySt. Louis, MO De Novo Lipogenesis and Metabolic Stress
November 4, 2009 John Y-J. Shyy, Ph.D. Professor of Biomedical Sciences University of CaliforniaRiverside, CA Flow-Activated AMPK and Endothelial Homeostasis
November 10, 2009 Helen H. Hobbs, M.D. Howard Hughes Investigator; Director, McDermott Centerfor Human Growthand Development; Chief, Division of Clinical Genetics, Internal Medicine University of Texas Southwestern Medical Center,Dallas, TX The Spectrum of Genetic Factors Contributing to Plasma Levels of LDL-Cholesterol
November 13, 2009 Leonard P. Guarente, Ph.D. Novartis Professorof Biology, Glenn Laboratory for the Science of Aging Massachusetts Institute of TechnologyCambridge, MA Sirtuins, Aging and Disease
November 24, 2009 Paul M. Vanhoutte, M.D., Ph.D. Department of Pharmacology Li Ka Shing Faculty of MedicineHong Kong The Fate of Regenerated Endothelial Cells:  Born to be Old!
November 25, 2009 Philip Eaton, Ph.D. The Rayne Institute St. Thomas’ HospitalKing’s CollegeLondon, U.K. Mechanisms of Oxidant Sensing and Signaling in the Cardiovascular System
December 1, 2009 Jorge Plutzky, M.D. Associate Professorof Medicine, Division of Cardiovascular Medicine Harvard Medical SchoolBrigham & Women’s HospitalBoston, MA The PPAR-RXR Transcriptional Complex:  Linking Energy Balance to Inflammation, Atherosclerosis and Diabetes?
December 8, 2009 William C. Stanley, Ph.D. Professor and Director of Cardiovascular Sciences University of MarylandBaltimore, MD Mitochondrial Dysfunction in Heart Failure:  Pathological Mechanisms and Therapeutic Opportunities
December 15, 2009 Christopher Sucato, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA PEGylated Nanoparticle Synthesis and Characterization, and Effects on Cultured Vascular Smooth Muscle CellsA Work-in-Progress Presentation
December 22, 2009 Ruhul Abid, M.D., Ph.D. Assistant Professorof Medicine Harvard Medical SchoolThe Center for Vascular Biology ResearchBeth Israel DeaconessMedical Center Coordination of Endothelial Signal Transduction:  Roleof Redox
Year 2010
January 12, 2010 Mukesh K. Jain, M.D. Director, Case Cardiovascular Research InstituteEllery Sedgwick Jr. Chair in Medicine Case Western Reserve UniversityCleveland, OH Crippling Cardiovascular Disease with Kruppels
January 22, 2010 Stephen Y. Chan, M.D., Ph.D. Instructor of Medicine Harvard Medical School and Massachusetts General HospitalBoston, MA MicroRNA-210 Controls Mitochondrial Metabolism and Hypoxic Adaptation in Pulmonary Vascular Endothelium
January 26, 2010 John J. Mieyal, Ph.D. Professor and Vice Chairmanof Pharmacology;  Director, Molecular Therapeutics Training Program Case Western Reserve UniversityCleveland, OH Redox Regulation by Reversible Protein S-Glutathionylation: Implications for the Aging Heart
January 28, 2010 Andreas Daiber, Ph.D. Professor,Molecular Cardiology Johannes Gutenberg UniversitätMainz, Germany Nitrate Tolerance and Mitochondrial Dysfunction:  Role for ALDH-2 and Cross-Talk Between Mitochondrial ROS and NADPH Oxidase
February 16, 2010 William T. Gerthoffer, Ph.D. Professor and ChairDepartment of Biochemistry & Molecular Biology University of South AlabamaMobile, AL MicroRNAs That Determine Smooth Muscle Phenotype
February 23, 2010 Aaron B. Baker, Ph.D. Biomedical Engineering Center,  Division of Health Sciences and Technology Harvard Medical School and Massachusetts Institute of TechnologyBoston, MA The Role of Heparanase and Syndecans in Vascular Remodeling
March 2, 2010 Thomas L. Force, M.D. James C. Wilson Professor of Medicine Clinical Director, Jefferson Centerfor Translational MedicinePhiladelphia, PA Re-Defining the Role of the GSK-3 Family of Kinases in the Heart:  Post-MI Remodeling, Adrenergic Responsiveness and Cardiomyocyte Proliferation
March 9, 2010 Hongjie Chen, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA A New Role for the A2b Adenosine Receptor in Regulating Platelet FunctionA Work-in-Progress Presentation
March 9, 2010 Eric Essick, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA Adiponectin:  Cardioprotection Against Oxidative StressA Work-in-Progress Presentation
March 23, 2010 Scott W. Ballinger, Ph.D. Associate ProfessorDepartment of Pathology; Director, Bio-analytical Redox Biology Core Bio-analytical Redox Biology CoreUniversity of AlabamaBirmingham, AL The Role of Mitochondrial Function in the Development of Cardiovascular Disease
April 6, 2010 Jesse Lugus, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA Energy Sensing Through Myokines:  A Chemokine with a Role in Skeletal Muscle Energy HomeostasisA Work-in-Progress Presentation
April 6, 2010 Duncan Sousa, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA Electron Microscopy and Persistence Length Analysis of Semi-Rigid Smooth Muscle Tropomyosin StrandsA Work-in-Progress Presentation
April 20, 2010 Mark A. Febbraio, Ph.D. Head of Basic Science, Division of Metabolism and Obesity Baker IDI Heartand Diabetes InstituteMelbourne, Australia “Role of Myokines in Metabolic Regulation”
May 4, 2010 Victor J. Dzau, M.D. Chancellorfor Health Affairs Duke UniversityDurham, NC “Repairing and Rejuvenating the Damaged Heart”
May 11, 2010 Jordan T. Shin, M.D., Ph.D. Instructor in Medicine Harvard Medical SchoolMassachusetts General HospitalBoston, MA “Zebrafish Insights Into Heart and Vascular Disease”
May 18, 2010 Ivan Luptak, M.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA “Lipotoxicity and Diastolic Dysfunction: Role of 4-hydroxynonenal and Uncoupled nNOS”A Work-in-Progress Presentation
May 18, 2010 Mustali Dohadwala, M.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA To be AnnouncedA Work-in-Progress Presentation
May 21, 2010 Peter Brouckaert, M.D., Ph.D. Professor, Ghent University Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium “Molecular Mechanisms of Inflammatory Shock: A Role for NO, sGC and Reactive Oxygen Species?”
May 25, 2010 Charles J. Lowenstein, M.D. Chief, Departmentof Medicine Director, Aab Cardiovascular Research Institute Paul N. Yu Professorship in Cardiology University of RochesterSchool of Medicine and DentistryRochester, NY “Nitric Oxide Regulation of Vascular Inflammation”
June 1, 2010 Lea Beaulieu, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA To be Announced
June 1, 2010 Dr. Bo Yang Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA To be Announced
June 15, 2010 Pere Puigserver, Ph.D. Associate Professorof Cell Biology Harvard Medical SchoolDana-Farber Cancer InstituteBoston, MA To be Announced
June 22, 2010 Melissa Farb, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA To be AnnouncedA Work-in-Progress Presentation
June 22, 2010 Kenneth Barth, Ph.D. Postdoctoral Research Fellow, Whitaker Cardiovascular Institute Boston UniversitySchool of MedicineBoston, MA To be AnnouncedA Work-in-Progress Presentation
2008 – 2009
2008
Date Speaker Name Affiliation Title of Talk
9-Sep-08 Dr. Santiago Lamas Spanish National Research Council, Madrid Regulation of Endothelin-1 mRNA Stability by a Redox-Based Mechanism: S-Thiolation of GAPDH
10-Sep-08 Dr. Mansoureh Eghbali UCLA, David Geffen School of Medicine Estrogen and Cardiac Protection: Insight on Its Mechanism
16-Sep-08 Dr. Paul Brookes University of Rochester Medical Center Mitochondria, Nitric Oxide and Cardioprotection: from Organelle to Organism
23-Sep-08 Dr. Francis J. Miller University of Iowa, Carver College of Medicine NADPH Oxidases and Signaling Endosomes in the Activiation of Vascular Smooth Muscle Cells
30-Sep-08 Dr. Timothy E. Graham Harvard Medical School Retinol Binding Protein-4 and Insulin Resistance: New Insight Into Normal Physiology and Cellular Mechanism
8-Oct-08 Dr. Nikolaos G. Frangogiannis Baylor College of Medicine, Houston Inflammation, Fibrosis and Cardiac Remodeling
14-Oct-08 Dr. Piero Anversa Harvard Medical School Progenitor Cells and Cardiac Repair
16-Oct-08 Dr. Paul M. Vanhoutte Li Ka Shing Faculty of Medicine, Hong Kong Endothelium-Derived Contracting Factor: When a Good Guy Turns Bad!
21-Oct-08 Dr. Agnes Bergerat Postdoctoral Research Fellow, WCVI, BUSM Proteomics of Brain Microvessels in a Hypertensive and Hyperlipidemic Rat Stroke Model
5-Nov-08 Dr. Edward A. Fisher New York University School of Medicine The Regression of Atherosclerosis: New Insights from Novel Mouse Models
18-Nov-08 Dr. Christopher Sucato* Postdoctoral Research Fellow, WCVI, BUSM Iron Oxide Nanoparticles as MRI Contrast Agents, and In Vivo Imaging of Plaque in a Rabbit Model of Atherosclerosis
2-Dec-08 Dr. E. Dale Abel University of Utah Insulin and Growth Factor Signaling in the Heart
16-Dec-08 Dr. Junichi Sadoshima University of New Jersey Medical School Redox Regulation of Cardiac Hypertrophy
6-Jan-09 Dr. Frank Naya Boston University, Department of Biology Requirement of the MEF2 Target Gene Myomaxin in Angiotensin II Induced Cardiomyopathy
13-Jan-09 Dr. George King Joslin Diabetes Center Is Insulin’s Actions on the Endothelium Anti-Atherogenic or Pro-Atherogenic
20-Jan-09 Dr. Arya Mani Yale University School of Medicine A Single Gene at the Crossroads of Metabolic Phenotypes and Cardiac Remodeling
2-Feb-09 Dr. Christian Kupatt Ludwig Maximilians University of Munich Role of AKT in Vascular Remodeling of Ischemic Tissue
3-Feb-09 Dr. Charles N. Serhan Brigham & Women’s Hospital A Systems Approach to Acute Inflammation Reveals a New Genus of Anti-Inflammatory and Pro-Resolving Mediators: Resolvins and Protectins
6-Feb-09 Dr. P. Christian Schulze Columbia University Medical Center Myocardial and Skeletal Muscle Metabolism and Proteolysis in Heart Failure
10-Feb-09 Dr. M. Isabel Dominquez BUSM, Hematology-Oncology Section To Be Announced
17-Feb-09 To Be Announced To Be Announced To Be Announced
24-Feb-09 Dr. Joseph A. Hill University of Texas Southwestern Pathological Cardiac Remodeling: Mechanisms and Therapies
3-Mar-09 Dr. Toren Finkel National Institutes of Health To Be Announced
10-Mar-09 Dr. John Griffin Scripps Institute To Be Announced
17-Mar-09 Dr. Roberta Gottlieb BioScience Center, San Diego State Univ. To Be Announced
24-Mar-09 Dr. Thomas Michel Brigham & Women’s Hospital To Be Announced
31-Mar-09 Dr. Mark Sussman San Diego State University To Be Announced
7-Apr-09 Dr. Lea Beaulieu* Postdoctoral Research Fellow, WCVI, BUSM To Be Announced
7-Apr-09 Dr. Bo Yang* Postdoctoral Research Fellow, WCVI, BUSM To Be Announced
14-Apr-09 Dr. Ji Li University of Wyoming, School of Pharmacy To Be Announced
21-Apr-09 Dr. Reto Asmis University of Texas Health Science Center Thiol Redox Signaling in Macrophage Dysfunction and Atherosclerosis
28-Apr-09 Dr. Michael Carroll Harvard Medical School To Be Announced
5-May-09 Dr. Jesse Lugus* Postdoctoral Research Fellow, WCVI, BUSM To Be Announced
5-May-09 Dr. Duncan Sousa* Postdoctoral Research Fellow, WCVI, BUSM To Be Announced
12-May-09 Dr. Eugene Valsky* Postdoctoral Research Fellow, WCVI, BUSM To Be Announced
19-May-09 Dr. Lorrie Kirshenbaum University of Manitoba To Be Announced
26-May-09 Dr. Mustali Dohadwala* Postdoctoral Research Fellow, WCVI, BUSM To Be Announced
26-May-09 Dr. Ivan Luptak* Postdoctoral Research Fellow, WCVI, BUSM To Be Announced
2-Jun-09 Dr. Roger Hajjar Albert Einstein To Be Announced
9-Jun-09 To Be Announced To Be Announced To Be Announced
16-Jun-09 Dr. Richard T. Lee To Be Announced To Be Announced
23-Jun-09 Dr. Xuebin Qin Harvard Medical School Complement Regulator CD59 in Vascular Diseases
Postponed Dr. Gideon Koren Brown Univ., Warren Alpert Medical School Postponed from November 4th. New Date to be Announced.
2007 – 2008
Date Speaker Name Affiliation Title of Talk
18-Jul-07 Jay L. Zweier, M.D. The Ohio State University Salvaging Heart Muscle at Risk in Acute Myocardial Infarction: Mechanisms and New Insights
18-Sep-07 David Y. Hui, Ph.D. University of Cincinnati College of Medicine Apolipoprotein E and Its Receptors in Atherosclerosis, Obesity and Diabetes
25-Sep-07 Balz Frei, Ph.D. Linus Pauling Institute, Corvallis, Oregon Lipoic Acid: An Effective Anti-Inflammatory and Anti-antiatherosclerotic Agent
2-Oct-07 Saad Ahmad, M.D. Postdoctoral Research Fellow, WCVI, BUSM Central ά2B Adrenoceptor and Hypertension: Transgenic Mice with Brain Selective Overexpression of the ά2B AR
16-Oct-07 Jay D. Horton, M.D. University of Texas Southwestern, Dallas PCSK9′s Role in Regulating Plasma LDL Cholesterol Levels
23-Oct-07 Yibin Wang, Ph.D. UCLA, David Geffen School of Medicine Novel Protein Phosphatases in Stress Regulation – Beauty in Ugly Ducklings
30-Oct-07 Agnes Bergerat, Ph.D. Postdoctoral Research Fellow, WCVI, BUSM Proteomic Changes in Brain Microvessels in Rats Prone to Stroke
13-Nov-07 Stephen G. Young, M.D. UCLA, David Geffen School of Medicine A New Paradigm for Chylomicron Metabolism
20-Nov-07 Tamar R. Aprahamian, Ph.D. Postdoctoral Research Fellow, WCVI, BUSM Lupus and Atherosclerosis: Modulation of Inflammatory Responses by Rosiglitazone and Adiponectin
4-Dec-07 Ira J. Goldberg, M.D. Columbia University Fat in the Heart, Getting It In – Storing It Up
11-Dec-07 Sherene Shenouda, Ph.D. Postdoctoral Research Fellow, WCVI, BUSM Mitochondrial and Endothelial Function in CAD
15-Jan-08 Mark L. Entman, M.D. Baylor College of Medicine, Houston, Texas The Cardiac Fibroblast in Non-Adaptive Fibrosis and in Cardiac Repair: Different Origins?
29-Jan-08 Meghan Kelly, Ph.D. Postdoctoral Research Fellow, WCVI, BUSM Novel Aspects of IL-6 Signaling and Its Relation to AMPK Activity
19-Feb-08 David A. Sinclair, Ph.D. Harvard Medical School Genes and Small Molecules that Extend Lifespan: Effects on Cardiovascular Disease
18-Mar-08 Reuben Shaw, Ph.D. The Salk Institute for Biological Studies, LaJolla The LKB1 Kinase: Tumor Suppressor and Key Regulator of AMPK and Metabolism
25-Mar-08 Frank J. Giordano, M.D. Yale University School of Medicine Mechanisms of Myocardial Angiogenesis; Development of Therapeutic Cardiovascular Gene Delivery Strategies
1-Apr-08 Nikolaos G. Frangogiannis, M.D. Baylor College of Medicine, Houston, Texas Inflammatory Mechanisms in Infarct Healing and Cardiac Remodeling
4-Apr-08 Ming-Hui Zou, M.D., Ph.D. University of Oklahoma Health Science Center Regulation of the AMP-Activated Protein Kinase
15-Apr-08 Bo Yang, M.D., Ph.D. Postdoctoral Research Fellow, WCVI, BUSM The New Role of Store-Operated Ca2+ Entry in Proliferation and Migration of Vascular Smooth Muscle Cells
22-Apr-08 Lea M. Beaulieu, Ph.D. Postdoctoral Research Fellow, WCVI, BUSM Innate Immunity: Modulation of Megakaryocytic Function
6-May-08 Nanette Bishopric, M.D. University of Miami p300 as a Nodal Regulator of the Myocardial Stress Response
13-May-08 James Kirkland, M.D., Ph.D. Kogod Center of Aging, Mayo Clinic Do Aging, Obesity and Replicative Stress Make Fat Go MAD?
27-May-08 Serge Smirnov, Ph.D. Postdoctoral Research Fellow, WCVI, BUSM Structure and Dynamics of Villins and Supervillins: Modular, Cytoskeleton Regulating Proteins
3-Jun-08 Eugene B. Valsky, M.D. Postdoctoral Research Fellow, WCVI, BUSM Post Translational Modifications Regulate Isolated Myocyte Contractility
17-Jun-08 Rong Tian, M.D., Ph.D. Harvard Medical School Energy Metabolism and Pathogenesis of Cardiomyopathy
27-Jun-08 Seemantini Nadkarni, Ph.D. Harvard Medical School Optical Imaging of Atherosclerosis: A Multifactorial Perspective
January 10, 2006 Jonathan G. Seidman, PhD Henrietta B. and Frederick H. Bugher, Professor of Cardiovascular Genetics, Department of Genetics, Harvard Medical School Cardiomyopathy in Mice and Men
January 24, 2006 Oscar Carretero, MD Division Head, Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, Michigan Hypertension, Inflammation and ACE Inhibitors
February 7, 2006 Clay F. Semenkovich, MD Professor of Medicine and Cell Biology & Physiology, Chief, Division of Endocrinology, Metabolism & Lipid Research, Washington University School of Medicine, St. Louis, MO Metabolic Syndrome and Vascular Disease
February 14, 2006 Elizabeth O. Harrington, PhD Associate Professor of Medicine, Pulmonary Vascular Research Laboratory, Brown Medical School, Providence, RI PKCdelta Modulation of Endothelial Barrier Function
February 21, 2006 Ronglih Liao, PhD Director, Cardiac Muscle Research Laboratory, Associate Professor of Medicine, Cardiovascular Division, Brigham and Women’s Hospital Adult Stem Cells and Cardiac Regeneration: A Tale of (im) Migration and Naturalization
March 7, 2006 Mathias Gautel, MD Professor of Molecular Cardiology, Head, Muscle Cell Biology, Cardiovascular Division, King’s College London, United Kingdom Mechanically Modulated Signalling by the Giant Muscle Protein Titin
March 21, 2006 Ulrich Schmidt, MD, PhD Assistant Professor of Anesthesia, Harvard Medical School, Assistant Director for Research , Critical Care Medicine, MGH. Myocardial Dysfunction and Calcium Signaling in Aging
March 28, 2006 Mona Nemer, PhD Professor, Department of Pharmacology, Director, Laboratory of Cardiac Growth and Differentiation, Instiut de recherches cliniques de Montreal, Canada Regulatory Networks controlling Normal and Pathologic Cardiac Growth
April 4, 2006 Noriyuki Ouchi, MD, PhD Assistant Professor, Molecular Cardiology, Whitaker Cardiovascular Institute, Boston University School of Medicine Cardioprotective Action of Adiponectin
April 11, 2006 Roger H. Unger, MD Director, Touchstone Center for Diabetes Research, Professor of Internal Medicine, UT Southwetern Medical Center at Dallas Lipotoxic Cardiomyopathy in the Metabolic Syndrome. Why We Are Losing the Compromise between Fasting and Feasting.
April 25, 2006 Joseph W. Sanger, PhD Professor and Chair Department Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, New York How to Build a Myofibril
May 2, 2006 Ellen O. Weinberg, PhD Assistant Professor, Department of Medicine, Cardiovascular Research, Boston University School of Medicine Innate Immune Signaling in the Cardiovascular System
May 16, 2006 Robert J. Schwartz, PhD Associate Director and Professor Institute of Biosciences and Technology, Texas A&M University Health Science Center, Houston, Texas Serum Response Factor: Roles in Cardiovascular Development and Disease
May 23, 2006 Cam Patterson, MD, FACC Ernest and Hazel Craige Distinguished Professor of Cardiovascular Medicine, Chief, Division of Cardiology, Founding Director, Carolina Cardiovascular Biology Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC Some New Ideas about Cardiac Hypertrophy
May 30, 2006 Karen K. Hirschi, PhD Associate Professor, Departments of Pediatrics and Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas Specification and Regulation of Hemogenic Endothelium
June 6, 2006 Nathan Kyle LeBrasseur, PhD Assistant Professor of Medicine, Section of Endocrinology, Diabetes & Nutrition, Boston University School of Medicine Tales and Targets of Muscle growth & Metabolism
June 27, 2006 David R. Pimentel, MD Assistant Professor of Medicine, Whitaker Cardiovascular Institute, Boston University School of Medicine Oxidative Signaling: Is it Radical to Think of More Than Modifications?
September 12, 2006 Vassilis Zannis, PhD Professor of Medicine and Biochemistry, Director, Molecular Genetics Unit, Boston University School of Medicine The Role of apoE in Lipid Homeostasis, in HDL Biogenesis and in Atherosclerosis
September 19, 2006 Michael Rosenzweig, MD “Work in Progress” Hematology/ Oncology Fellow, Boston Medical Center Cardiac Amyloidosis: Searching for a Treatment
September 26, 2006 Benjamin G. Neel MD, PhD Professor of Medicine, Director, Cancer Biology Program, Beth Israel Deaconess Medical Center, Boston, MA Tyrosine Phosphatases in Health and Disease
October 24, 2006 Bernadette O. Fernandez, PhD “Work in Progress” Postdoctoral Research Fellow, Whitaker Cardiovascular Institute, Boston University School of Medicine NObonomics: a Newfangled Nature of Nitric Oxide and its Metabolites
October 31, 2006 Lawrence H. Young, MD Professor of Medicine, Section of Cardiovascular Medicine, Yale University Medical School, New Haven, Connecticut AMP-activated Protein Kinase in the Ischemic Heart
November 7, 2006 Laura E. Benjamin, PhD Associate Professor, Department of Pathology and Center for Vascular Biology, Beth Israel Deaconess Medical Center, Harvard Medical School Akt Signaling in the Vasculature
November 21, 2006 Vladislav Zarayskiy, PhD “Work in Progress” Postdoctoral Research Fellow, Whitaker Cardiovascular Institute, Ion Channel and Calcium Signaling Unit, Boston University School of Medicine Store-operated Channels and IP3 Receptor-operated Channels: Molecular Identity and Mechanism of Activation
November 28, 2006 Hanjoong Jo, PhD Professor, Coulter Department of Biomedical Engineering at Georgia Tech and Emory, Emory University Does Disturbed Flow Induce Atherosclerosis and Hypertension? Role of BMP4
December 5, 2006 Alan Richard Tall, MD Tilden-Weger-Bieler Professor of Medicine, Professor of Physiology and Cellular Biophysics, Columbia University Medical Center Mechanisms Responsible for the Protective Effect of HDL in Atherosclerosis
December 12, 2006 Arya Mani, MD Assistant Professor of Medicine, Yale University School of Medicine Genetic Approach to Vascular Remodeling
December 19, 2006 Philipp E. Scherer, PhD Professor, Departments of Cell Biology and Medicine, Division of Endocrinology, Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, NY Adipocytes: Innocent Bystanders or Chief Culprits of Metabolic Disease?
January 9, 2007 Steven R. Houser, PhD, FAHA Laura H. Carnell Professor of Physiology, Director, Cardiovascular Research Center, Temple University-School of Medicine, Philadelphia, PA Ca2+ Influx and the Generation of New Cardiac Myocytes
January 16, 2007 Daniel R. Goldstein, MBBS Assistant Professor of Medicine, Yale University School of Medicine Aging, Innate Immunity and Transplantation
January 23, 2007 Steven R. Lentz, MD, PhD Hamilton Professor of Hematology, Interim Director, Division of Hematology, Oncology and Blood & Marrow Transplantation, The University of Iowa, Iowa City, IA The Homocysteine Paradox
January 30, 2007 Jessica L. Grimsby, PhD “Work in Progress” Postdoctoral Research Fellow, Whitaker Cardiovascular Institute, Boston University School of Medicine Investigation of the Requirements for Proper Folding, Secretion and Activity of Lysyl Oxidase
February 6, 2007 Donald M. Bers, PhD James R. DePauw Professor of Physiology, Chair, Department of Physiology, Loyola University Chicago, Maywood, Illinois Calcium and CaMKII in Cardiac Myocytes: Role in Heart Failure and Arrhythmias
February 20, 2007 John E. Hall, PhD Arthur C. Guyton Professor and Chair, Department of Physiology & Biophysics, Director, Center of Excellence in Cardiovascular-Renal Research, Associate Vice Chancellor of Research, University of Mississippi Medical Center, Jackson, MS Pathophysiology of Hypertension in Obesity/Metabolic Syndrome
February 27, 2007 Nicholas K. Tonks, PhD, FRS Professor, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York Regulation of Signal Transduction by Protein Tyrosine Dehosphorylation
March 6, 2007 Sherene Shenouda, PhD “Work in Progress” TBA TBA
March 20, 2007 Tamar Aprahamiam “Work in Progress” Boston University School of Medicine TBA
March 27, 2007 Jan E. Schnitzer, MD Scientific Director, Professor of Cellular & Molecular Biology, Director of Vascular Biology & Angiogenesis Program, Sidney Kimmel Cancer Center, SanDiego, CA Proteomic Imaging of Luminal Endothelial Surfaces and Caveolae in Vivo: Delivery Pathway into Specific Organs and solid Tumors
April 10, 2007 Brian O’Rourke, PhD Professor of Medicine, Johns Hopkins University School of Medicine, Institute of Molecular Cardiobiology, Baltimore, MD TBA
April 17, 2007 Meghan Kelly & Eugene Valsky “Work in Progress” Boston University School of Medicine TBA
May 1, 2007 Jan L. Breslow, MD Professor, Rockefeller University, Head, Laboratory of Biochemical Genetics and Metabolism, Senior Physician, Rockefeller Hospital, Rockefeller University, New York, NY Genetics of Atherosclerosis; Studies in Humans and Mice
May 22, 2007 Morton Printz University of California at San Diego TBA
June 5, 2007 Parker B.Antin, PhD Professor, Department of Cell Biology and Anatomy, Molecular Cardiovascular Research Program, University of Arizona School of Medicine, Tucson, AZ Epithelial-Mesenchymal Transitions in Development: from Candidate Genes to Regulatory Networks

CVI Seminars 2005-2006 (attended by trainees in the Cardiovascular Training Program)

September 13, 2005 Pascal J. Goldschmidt, MD, FACC Chair, Department of Medicine, Duke University Medical Center, Durham, North Carolina Failure of Arterial Repair with Aging Leads to Atherosclerosis…..
October 4, 2005 Daniel P. Kelly, MD Alumni Endowed Professor in Cardiovascular Diseases. Director, Center for Cardiovascular Research, Washington University School of Medicine, St. Louis, MO Nuclear Receptor Signaling in the Normal and Failing Heart
October 25, 2005 Mark B. Taubman, MD Paul N. Yu Professor of Medicine. Chief, Division of Cardiology, University of Rochester Medical Center New Paradigms in Tissue Factor Biology: Its Role in Ischemia, Arterial Injury, and Pulmonary Hypertension
November 1, 2005 Joyce J. Repa, PhD Assistant Professor, Departments of Physiology and Internal Medicine. UT Southwestern Medical Center, Dallas, Texas Role of Orphan Nuclear Receptors in Cholesterol Homeostasis
November 8, 2005 Cecilia W. Lo, PhD Chief, Laboratory of Development Biology. Director, Genetics and Developmental Biology Center, NHLBI, NIH, Bethesda, MD The Genetic Basis for Congenital Heart Disease
November 29, 2005 Andrew S. Weyrich, PhD Associate Professor of Internal Medicine. Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT Novel Functions of Megakaryocytes and Platelets: Splicing in the Cytoplasmic Milieu
December 6, 2005 Helen H. Hobbs, MD Investigator, Howard Hughes Medical Institute. Professor of Internal Medicine and Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas Genetics of Lipoproteins and Atherosclerosis
December 13, 2005 Michael Simons, MD A.G. Huber Professor of Medicine, Professor of Pharmacology and Toxicology. Chief, Section of Cardiology. Director, Angiogenesis Research Center, Dartmouth Medical School, Dartmouth Hitchcock Medical Center Regulation of Arteriogenesis
January 10, 2006 Jonathan G. Seidman, PhD Henrietta B. and Frederick H. Bugher Professor of Cardiovascular Genetics, Department of Genetics, Harvard Medical School Cardiomyopathy in Mice and men
January 24, 2006 Oscar Carretero, MD Division Head, Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, Michigan Hypertension, Inflammation and ACE Inhibitors
February 7, 2006 Clay F. Semenkovich, MD Professor of Medicine and Cell Biology & Physiology. Chief, Division of Endocrinology, Metabolism & Lipid Research, Washington University School of Medicine, St. Louis, MO Metabolic Syndrome and Vascular Disease
February 14, 2006 Elizabeth O. Harrington, PhD Associate Professor of Medicine, Pulmonary Vascular Research Laboratory, Brown Medical School, Providence, RI PKC Delta Modulation of Endothelial Barrier Function
February 21, 2006 Ronglih Liao, PhD Director, Cardiac Muscle Research Laboratory, Associate Professor of Medicine, Cardiovascular Division, Brigham and Women’s Hospital Adult Stem Cells and Cardiac Regeneration: A Tale of (im) Migration and Naturalization
March 7, 2006 Mathias Gautel, M.D. Professor of Molecular Cardiology, Head, Muscle Cell Biology, Cardiovascular Division, King’s College London, United Kingdom Mechanically Modulated Signalling by the Giant Muscle Protein Titin
March 14, 2006 Karen K. Hirschi, Ph.D. Associate Professor, Departments of Pediatrics and Molecular & Cellular Biology, Baylor College of Medicine Specification and Regulation of Hemogenic Endothelium
March 21, 2006 Ulrich Schmidt, M.D., Ph.D. Massachusetts General Hospital TBN
March 28, 2006 Mona Nemer, Ph.D. Professor, Department of Pharmacology, Director, Laboratory of Cardiac Growth and Differentiation, Institut de recherches cliniques de Montreal, Canada Regulatory Networks Controlling Normal and Pathologic Cardiac Growth
April 4, 2006 Noriyuki Ouchi, M.D., Ph.D. Boston University School of Medicine TBN
April 11, 2006 Roger H. Unger, M.D. Touchstone/West Distinguished Chair in Diabetes Research,Director, Touchstone Center for Diabetes Research, Professor of Internal Medicine at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center Lipotoxic Cardiomyopathy in the Metabolic Syndrome. Why We are Losing the Compromise between Fasting and Feasting.
April 18, 2006 Steven R. Houser, Ph.D. Laura H. Carnell Professor of Physiology, Director, Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, PA TBN
April 25, 2006 Joseph W. Sanger, Ph.D. Chair and Professor of Cell and Developmental Biology, SUNY Upstate Medical University TBN
May 2, 2006 Ellen O. Weinberg, Ph.D. Boston University School of Medicine TBN
May 16, 2006 Robert J. Schwartz, Ph.D. Baylor College of Medicine TBN
May 23, 2006 Cam Patterson, M.D. University of North Carolina TBN
June 6, 2006 Nathan K. LeBrasseur, Ph.D. Boston University School of Medicine TBN
June 20, 2006 David R. Pimental, M.D. Boston University School of Medicine TBN

CVI Seminars 2004-2005 (attended by trainees in the Cardiovascular Training Program)

September 14, 2004 Joseph R. Williamson, MD Professor of Pathology, Pathology Department, Washington University School of Medicine, St. Louis, MO Caveats to Connecting Metabolic Imbalances Implicated in Diabetic Complications September 15, 2004 Takeshi Adachi, MD, PhD Research Assistant Professor, Vascular Biology Unit, Boston University Medical Center The Mechanism of Nitric Oxide-induced Arterial Relaxation October 5, 2004 Richard N. Kitsis, MD Professor of Medicine and Cell Biology, The Dr. Gerald and Myra Dorros Chair in Cardiovascular Disease, Director, Cardiovascular Research Center, Albert Einstein College of Medicine, New York City, NY Manipulating Cell Death in Heart Disease October 19, 2004 Robert S. Balaban, PhD Scientific Director, Laboratory Research Program, NHLBI, Bethesda, MD The Cellular Domestication of Mitochondrial Function October 26, 2004 Heinrich Taegtmeyer, MD, D Phil Professor of Medicine, Department of Internal Medicine/Division of Cardiology, University of Texas Health Science Center at Houston, Houston, Texas Multitasking of Myocardiol Metabolism November 3, 2004 Malte Kelm, MD Professor of Cardiology and Vascular Medicine, Deputy Chair of the Division of Cardiology, Pulmonary and Vascular Medicine, Heinrich Heine University Dusseldorf, Germany Transport and Synthesis of Nitric Oxide in Human Circulation November 4, 2004 Kostas Pantopoulos, PhD Associate Professor, Department of Medicine, Division of Experimental Medicine, McGill University, Montreal, Canada Iron Metabolism, Cancer and Hepatitis C Virus: New Regulatory Connections November 16, 2004 Michael S. Goligorsky, MD, PhD Professor of Medicine and Pharmacology, Academic Chief, Division of Nephrology, Director, Renal Research Institute, Basic Sciences Building, Valhalla, NY Premature Senescence of Vascular Endothelial cells December 7, 2004 Anthony Rosenzweig, MD Director, Program in Cardiovascular Gene Therapy, MGH Signaling Pathways Controlling Cardiomyocyte Survival and Function December 14, 2004 Paul Wentworth, Jr., PhD Professor of Medicinal Chemistry, University of Oxford, UK, Professor, Department of Chemistry, The Scripps Research Institute, LaJolla, CA Cholesterol 5, 6-secosterols (the Atheronals)-A Chemical Link between Atherosclerosis and Alzheimer’s Disease January 11, 2005 Douglas W. Losordo, MD Chief, Cardiovascular Research, St. Elizabeth’s Medical Center, Professor of Medicine, Tufts University School of Medicine, Boston, MA Adult Stem Cells: New Hope for Old Hearts? January 18, 2005 Elizabeth M. McNally, MD, PhD Associate Professor in the Departments of Medicine and Human Genetics, University of Chicago, Chicago, Illinois Molecular Determinants of Vascular spasm February 8, 2005 Bingbing Jiang, PhD Research Assistant Professor, Vascular Biology Unit, Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine Mitogen-activated Protein Kinases Regulate the Duration of NF-kB Activation February 15, 2005 Jon Epstein, MD Professor of Medicine, Cardiovascular Division, Hospital of the University of Pennsylvania, Pennsylvania, PA Translating Insights from Cardiac Development to Adult Cardiac Disease February 22, 2005 Alan Fine, MD Associate Professor of Medicine, Pulmonary Center, Boston University School of Medicine Lung Stem Cells: New Paradigms March 1, 2005 Kai Chen, MD, PhD Research Assistant Professor of Medicine, Whitaker Cardiovascular Institute, Boston University School of Medicine Reactive Oxygen Species and Signal Transduction March 8, 2005 Jennifer Van Eyk Director, The Hopkins NHLBI Proteomics Center, Director, Bayview Proteomics Group, Associate Professor Medicine, Division of Cardiology, Biological Chemistry and Biomedical Engineering, Johns Hopkins University-Bayview Campus, Baltimore, Maryland Expanding the Mitochondrial Proteome and its Implications in Cardiac Disease March 22, 2005 Jeffrey R. Moore Assistant Professor, Department of Physiology & Biophysics, Boston University School of Medicine The Role of the Myosin Neck Region April 5, 2005 Richard H. Karas, MD, PhD Associate Professor of Medicine, Tufts University School of Medicine, Co-director, Molecular Cardiology Research Center, Director, Preventive Cardiology Center, Director, Women’s Heart Center, Tufts-New England Medical Center, Boston, MA Estrogen, Estrogen Receptors and the Cardiovascular System April 12, 2005 Martin Feelisch, Ph.D. Professor of Medicine & Biochemistry, Whitaker Cardiovascular Institute, Boston University School of Medicine What the Heck is NObonomics? April 19, 2005 Sidney Morris, Jr., Ph.D. Professor of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, PA Roles and Regulation of Arginases: Relevance to Vascular Biology and Disease April 26, 2005 Angelo Parini, M.D., Ph.D. Director, Louis Bugnard Institute, Professor of Physiology, Head of the Molecular Pharmacology and Renal Pathophysiology Laboratory, Toulouse, France Hydrogen Peroxide Produced by Monoamine Oxidases: a Key Mediator of Receptor-independent Effects of Serotonin in the Heart May 3, 2005 Mohamad Navab, PhD Professor of Cardiology/Medicine, UCLA, Los Angeles, CA Using HDL Components as Anti-inflammatory Agents

CVI Seminars 2003-2004 (attended by trainees in the Cardiovascular Training Program)

2003 – 2004 Lunch is served at all lectures at 11:30, Speaker will begin at 12:00 EBRC Conference Room, X714, 650 Albany Street September 9, 2003 Jorge Plutzky, M.D., Director, The Vascular Disease Prevention Program, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, “Exogenous and Endogenous Mechanisms for PPAR Activation: Implications for Diabetes and Atherosclerosis” September 30, 2003 Philip W. Shaul, M.D., Professor of Pediatrics, UT Southwestern Medical Center at Dallas, Department of Pediatrics, “eNOS Regulation in Caveolae: Identifying the Battlefield and the Combatants in the War of Endothelial Function” October 7, 2003 Richard C. Austin, Ph.D., Associate Professor, Department of Pathology and Molecular Medicine, McMaster University, “Homocysteine-induced Endolplasmic Reticulum Stress and its Role in the Development of Atherosclerosis” November 18, 2003 Michael S. Wolin, Ph.D., Professor of Physiology, Department of Physiology, New York Medical College, “Roles for Oxidant and Redox Signaling Mechanisms in the Control of Vascular Function by PO2 and Stretch” December 2, 2003 Hanjoong Jo, Ph.D., Associate Professor, Coulter Department of Biomedical Engineering at Georgia Tech and Emory, Emory University, “BMP4 is a Mechanosensitive, Proatherogenic Cytokine in Endothelial Cells” December 9, 2003 Dennis J. Stuehr, Ph.D., Professor of Molecular Medicine, Department of Immunology, Lerner Research Institute, “Biological Protein Nitration: Identifying the Targets, Mechanisms, and Possible Consequences” December 16, 2003 George L. King, M.D., Professor of Medicine, Director of Research, Joslin Diabetes Center, Section Head: Vascular Cell Biology, “The Role of PKC Activation in the Cardiovascular Complications of Diabetes and Insulin Resistance Syndromes” January 6, 2004 Jeffrey Robbins, Ph.D., Professor of Pediatrics, Chair, Molecular Cardiovascular Biology, Associate Chair of Core Research Programs, Cincinnati Children’s Hospital Medical Center, “The Desmin-related Cardiomyopathies; Alzheimer’s of the Heart” January 20, 2004 Victor Darley-Usmar, Ph.D., Professor of Pathology, University of Alabama at Birmingham, “Nitric Oxide and Mitochondria; Mechanisms and Biological Implications” Feburary 10, 2004 Michael D. Schneider, M.D., The M.D. Anderson Foundation Professor, Center for Cardiovascular Development Departments of Medicine, Molecular and Cellular Biology, and Molecular Physiology and Biophysics, Baylor College of Medicine, “Cardiac Progenitor Cells from Adult Myocardium: Homing, Differentiation, and Fusion Following Infarction” March 9, 2004 Kirkwood A. Pritchard, Jr. Ph.D., Associate Professor of Pediatric Surgery, Medical College of Wisconsin, “eNOS Dysfunction in Hypercholesterolemia and Sickle Cell, A Common Theme between Two Dissimilar Genetic Diseases” March 23, 2004 Michael A. Marletta, Ph.D., Aldo DeBenedictis Distinguished Professor of Chemistry, Professor of Biochemistry and Molecular Biology, University of California, Berkeley, “Sensing Nitric Oxide in a Sea of Oxygen ¡§C How Does NO Signaling Work” April 6, 2004 Charles E. Murry, M.D., Ph.D., Associate Professor, Department of Pathology, University of Washington, Seattle, WA, “Stem Cells in Repair of the Injured Heart: Fact, Fiction or (con)fusion” April 13, 2004 Masuko Ushio-Fukai, Ph.D., Assistant Professor of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA “Reactive Oxygen Species and Angiogenesis” April 16, 2004 Takayuki Asahara, M.D., Ph.D., Director of Regenerative Medicine and Research, Kobe Institute of Biomedical Research and Innovation, RIKEN Center of Developmental Biology, Kobe, Japan “Endothelial Progenitor Cells for Regeneration” April 27, 2004 Frank J. Naya, Ph.D., Assistant Professor, Department of Biology, Program in Cell and Molecular Biology, Boston University, “The MEF2 Transcription Factor Pathway in Cardiac Development and Disease” May 11, 2004 Jeffery D. Molkentin, Ph.D., Associate Professor of Pediatrics, Cincinnati Children’s Hospital Medical Center University of Cincinnati, Cincinnati, Ohio “PKCalpha Functions as a Novel Regulator of Cardiac Contractility” May 25, 2004 William Aird, MD Director, Molecular Medicine Deaconess, Boston, MA Endothel specific gene regulation

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December 21, 2013
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